Radiation injury and gut microbiota-based treatment

Fecal microbiota transplantation from young mice rejuvenates aged hematopoietic stem cells by suppressing inflammation

(2023) Xiangjun Zeng et al.   BLOOD

Colonic Transendoscopic Enteral Tubing Is a New Pathway to Microbial Therapy, Colonic Drainage, and Host–Microbiota Interaction Research

(2023) Weihong Wang et al.   Journal of Clinical Medicine

Comparison of quality of life between elderly and non-elderly adult residents in Okuma town, Japan, in a post-disaster setting

(2023) Varsha Hande et al.   PLoS One

From microbial technology to microbiota medicine as a clinical discipline: Sustainable development goal

(2023) Faming Zhang et al.   Microbial Biotechnology

SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection

(2022) Paul Feuerstadt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22

(2022) Alexis Espinal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antibiotic-Induced Gut Microbiota Depletion Accelerates the Recovery of Radiation-Induced Oral Mucositis in Rats

(2022) Ghanyah Al-Qadami et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Lactobacillus reuteri Releasing IL-22 (LR-IL-22) Facilitates Intestinal Radioprotection for Whole-Abdomen Irradiation (WAI) of Ovarian Cancer

(2022) Diala F. Hamade et al.   RADIATION RESEARCH

Washed preparation of faecal microbiota changes the transplantation related safety, quantitative method and delivery

(2022) Gaochen Lu et al.   Microbial Biotechnology

Prospective Application of Ferroptosis in Hypoxic Cells for Tumor Radiotherapy

(2022) Jing Su et al.   Antioxidants

Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation

(2022) Brett I. Bell et al.   CANCER RESEARCH

Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation

(2022) Aurélien Trompette et al.   Mucosal Immunology

Maturing of public-private-people partnership (4P): Lessons from 4P for triple disaster and subsequently COVID-19 pandemic in Fukushima

(2022) Yurie Kobashi et al.   Journal of Global Health

TLR4 regulates RORγt+ regulatory T-cell responses and susceptibility to colon inflammation through interaction with Akkermansia muciniphila

(2022) Yaojiang Liu et al.   Microbiome

Sexual dimorphism in gut microbiota dictates therapeutic efficacy of intravenous immunoglobulin on radiotherapy complications

(2022) Zongkui Wang et al.   Journal of Advanced Research

Gut dysbiosis impairs hippocampal plasticity and behaviors by remodeling serum metabolome

(2022) Guoqiang Liu et al.   Gut Microbes

Eleutheroside E supplementation prevents radiation-induced cognitive impairment and activates PKA signaling via gut microbiota

(2022) Chen Song et al.   Communications Biology

Activation of pyroptosis and ferroptosis is involved in radiation-induced intestinal injury in mice

(2022) Feng Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile Infection

(2022) Sahil Khanna et al.   DRUGS

Extended Follow-up of Microbiome Therapeutic SER-109 Through 24 Weeks for Recurrent Clostridioides difficile Infection in a Randomized Clinical Trial

(2022) Stuart H. Cohen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Organic Acids Secreted by Lactobacillus spp. Isolated from Urine and Their Antimicrobial Activity against Uropathogenic Proteus mirabilis

(2022) Dominika Szczerbiec et al.   MOLECULES

Towards clinical translation of FLASH radiotherapy

(2022) Marie-Catherine Vozenin et al.   Nature Reviews Clinical Oncology

The Intestinal Microbiota: Our Best Frenemy in Radiation-Induced Damages?

(2021) Melissa C. Kordahi et al.   Cell Host & Microbe

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

(2021) Diwakar Davar et al.   SCIENCE

Alterations in skin microbiome mediated by radiotherapy and their potential roles in the prognosis of radiotherapy-induced dermatitis: a pilot study

(2021) Mohammed Ramadan et al.   Scientific Reports

Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage

(2021) Tao Cheng et al.   BLOOD

It takes a village: microbiota, parainflammation, paligenosis and bystander effects in colorectal cancer initiation

(2021) Xingmin Wang et al.   Disease Models & Mechanisms

The gut microbiota metabolite urolithin A inhibits NF-κB activation in LPS stimulated BMDMs

(2021) Khalid N. M. Abdelazeem et al.   Scientific Reports

Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells

(2021) Yong-Soo Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Impact of radiation-induced toxicities on quality of life of patients treated for head and neck cancer

(2021) Hans Paul van der Laan et al.   RADIOTHERAPY AND ONCOLOGY

Cardiovascular Manifestations From Therapeutic Radiation

(2021) Joshua D. Mitchell et al.   JACC: CardioOncology

Magnetic resonance linear accelerator technology and adaptive radiation therapy: An overview for clinicians

(2021) William A. Hall et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Microbiota modulate Doxorubicin induced cardiotoxicity

(2021) Lulu An et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Gut Microbiota-Derived l-Histidine/Imidazole Propionate Axis Fights against the Radiation-Induced Cardiopulmonary Injury

(2021) Zhiyuan Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut metabolite Urolithin A mitigates ionizing radiation‐induced intestinal damage

(2021) Yuanyang Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lactobacillus plantarum alleviates irradiation‐induced intestinal injury by activation of FXR‐FGF15 signaling in intestinal epithelia

(2021) Yong‐Ping Jian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Exposure to X-rays Causes Depression-like Behaviors in Mice via HMGB1-mediated Pyroptosis

(2021) Lixing Xu et al.   NEUROSCIENCE

Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models

(2021) Jiali Dong et al.   Cell Reports

Dysbiosis of Gut Microbiota Is Associated With the Progression of Radiation-Induced Intestinal Injury and Is Alleviated by Oral Compound Probiotics in Mouse Model

(2021) Tian-Shu Zhao et al.   Frontiers in Cellular and Infection Microbiology

Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome

(2021) Yuichi Nishiyama et al.   Genes

Altered Gut Microbiota Associated With Hemorrhage in Chronic Radiation Proctitis

(2021) Liangzhe Liu et al.   Frontiers in Oncology

Gut Microbiota-Derived PGF2α Fights against Radiation-Induced Lung Toxicity through the MAPK/NF-κB Pathway

(2021) Zhi-Yuan Chen et al.   Antioxidants

Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome

(2020) Isabelle R. Miousse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Enhancing Private Sector Health System Preparedness for 21st-Century Health Threats

(2020) Donald M. Berwick et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fecal microbiota transplantation: A promising treatment for radiation enteritis?

(2020) Xiao Ding et al.   RADIOTHERAPY AND ONCOLOGY

Washed microbiota transplantation vs. manual fecal microbiota transplantation: clinical findings, animal studies and in vitro screening

(2020) Ting Zhang et al.   Protein & Cell

Gut commensal derived-valeric acid protects against radiation injuries

(2020) Yuan Li et al.   Gut Microbes

Dermatologic Sequelae Associated with Radiation Therapy

(2020) Kurt A. Ashack et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8+ T cells in mice

(2020) Lijuan Wang et al.   GUT

The Intestinal Microbiota Plays as a Protective Regulator Against Radiation Pneumonitis

(2020) Xiaoqi Nie et al.   RADIATION RESEARCH

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

(2020) Hui-wen Xiao et al.   Microbiome

Roles for 53BP1 in the repair of radiation-induced DNA double strand breaks

(2020) Atsushi Shibata et al.   DNA REPAIR

Multi-donor multi-course faecal microbiota transplantation relieves the symptoms of chronic hemorrhagic radiation proctitis

(2020) Ya-Mei Zheng et al.   MEDICINE

Irradiation-Induced Intestinal Damage Is Recovered by the Indigenous Gut Bacteria Lactobacillus acidophilus

(2020) Panida Sittipo et al.   Frontiers in Cellular and Infection Microbiology

Prophylactic Faecalibacterium prausnitzii treatment prevents the acute breakdown of colonic epithelial barrier in a preclinical model of pelvic radiation disease

(2020) Alexia Lapiere et al.   Gut Microbes

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

(2020) Erez N. Baruch et al.   SCIENCE

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Gut microbiota: implications for radiotherapy response and radiotherapy-induced mucositis

(2019) Ghanyah Al-Qadami et al.   Expert Review of Gastroenterology & Hepatology

Gut microbial dysbiosis is associated with development and progression of radiation enteritis during pelvic radiotherapy

(2019) Zhongqiu Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity

(2019) Michele Russo et al.   EUROPEAN JOURNAL OF HEART FAILURE

Amiodarone induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts

(2019) Jie Weng et al.   BIOMEDICINE & PHARMACOTHERAPY

Microbiota and radiotherapy-induced gastrointestinal side-effects (MARS) study: a large pilot study of the microbiome in acute and late radiation enteropathy.

(2019) Miguel Reis Ferreira et al.   CLINICAL CANCER RESEARCH

Impact of Low-Dose Ionizing Radiation on the Composition of the Gut Microbiota of Mice

(2019) Xiaodan Liu et al.   TOXICOLOGICAL SCIENCES

Lactobacillus rhamnosusGG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells

(2018) Terrence E Riehl et al.   GUT

Faecalibacterium prausnitzii Produces Butyrate to Maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1

(2018) Lixing Zhou et al.   INFLAMMATORY BOWEL DISEASES

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

(2018) Sébastien Lucas et al.   Nature Communications

Microbiota transplantation: concept, methodology and strategy for its modernization

(2018) Faming Zhang et al.   Protein & Cell

Effect of Probiotics for the Prevention of Acute Radiation-Induced Diarrhoea Among Cervical Cancer Patients: a Randomized Double-Blind Placebo-Controlled Study

(2018) Ye Htut Linn et al.   Probiotics and Antimicrobial Proteins

Adjunctive Treatments for the Prevention of Chemotherapy- and Radiotherapy-Induced Mucositis

(2018) Michael Thomsen et al.   INTEGRATIVE CANCER THERAPIES

Therapy for prevention and treatment of skin ionizing radiation damage: a review

(2018) José L. Soriano et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

(2018) Yinghong Wang et al.   NATURE MEDICINE

Radiation-Induced Liver Disease and Modern Radiotherapy

(2018) Eugene J. Koay et al.   SEMINARS IN RADIATION ONCOLOGY

Protective Role of Nuclear Factor-Erythroid 2-Related Factor 2 Against Radiation-Induced Lung Injury and Inflammation

(2018) Xiaoli Tian et al.   Frontiers in Oncology

Hyperbaric oxygen treatment reverses radiation induced pro-fibrotic and oxidative stress responses in a rat model

(2017) N. Oscarsson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction

(2017) Shiran Gerassy-Vainberg et al.   GUT

Microbial cells can cooperate to resist high-level chronic ionizing radiation

(2017) Igor Shuryak et al.   PLoS One

Solid Cancer Incidence among the Life Span Study of Atomic Bomb Survivors: 1958–2009

(2017) Eric J. Grant et al.   RADIATION RESEARCH

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Radiation-Induced Liver Toxicity

(2017) Pablo Munoz-Schuffenegger et al.   SEMINARS IN RADIATION ONCOLOGY

The Potential Effect of Oral Microbiota in the Prediction of Mucositis During Radiotherapy for Nasopharyngeal Carcinoma

(2017) Xiao-Xia Zhu et al.   EBioMedicine

Hepatocellular carcinoma review: Current treatment, and evidence-based medicine

(2017) Bulent Karaman et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanisms

(2016) Katarzyna Jonak et al.   BMC Systems Biology

High-throughput 16S rRNA gene sequencing reveals alterations of mouse intestinal microbiota after radiotherapy

(2015) Young Suk Kim et al.   ANAEROBE

Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative status

(2015) Holger Klammer et al.   CANCER LETTERS

Akkermansia muciniphilaandHelicobacter typhloniusmodulate intestinal tumor development in mice

(2015) Celia Dingemanse et al.   CARCINOGENESIS

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Consequences of irradiation on bone and marrow phenotypes, and its relation to disruption of hematopoietic precursors

(2014) Danielle E. Green et al.   BONE

The Effect of Probiotics for Preventing Radiation-Induced Morphological Changes in Intestinal Mucosa of Rats

(2014) Yongkan Ki et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Radiation enteropathy—pathogenesis, treatment and prevention

(2014) Martin Hauer-Jensen et al.   Nature Reviews Gastroenterology & Hepatology

The Impact of Microbial Immune Enteral Nutrition on the Patients with Acute Radiation Enteritis in Bowel Function and Immune Status

(2013) Feng shao et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer

(2013) Sarah C. Darby et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Incidence of Leukemia, Lymphoma and Multiple Myeloma among Atomic Bomb Survivors: 1950–2001

(2013) Wan-Ling Hsu et al.   RADIATION RESEARCH

The Gut Microbiome Modulates Colon Tumorigenesis

(2013) J. P. Zackular et al.   mBio

An acute negative bystander effect of  -irradiated recipients on transplanted hematopoietic stem cells

(2012) H. Shen et al.   BLOOD

Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects

(2012) Tomonori Hayashi et al.   FASEB JOURNAL

IL-1 Generated Subsequent to Radiation-Induced Tissue Injury Contributes to the Pathogenesis of Radiodermatitis

(2012) Matthew Janko et al.   RADIATION RESEARCH

Antioxidant Properties of Probiotics and Their Protective Effects in the Pathogenesis of Radiation-Induced Enteritis and Colitis

(2010) Basileios G. Spyropoulos et al.   DIGESTIVE DISEASES AND SCIENCES

Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients

(2010) Imjai Chitapanarux et al.   Radiation Oncology

Inflammatory bowel disease, gut bacteria and probiotic therapy

(2009) Caroline Reiff et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY