Targeting cells of the immune system: mannosylated HPMA–LMA block-copolymer micelles for targeting of dendritic cells

Defining dendritic cells

(2015) Barbara U Schraml et al.   CURRENT OPINION IN IMMUNOLOGY

Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers

(2015) Theresa Frenz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Polymeric nanoparticles for co-delivery of synthetic long peptide antigen and poly IC as therapeutic cancer vaccine formulation

(2015) Sima Rahimian et al.   JOURNAL OF CONTROLLED RELEASE

Dissolving Microneedle Delivery of Nanoparticle-Encapsulated Antigen Elicits Efficient Cross-Priming and Th1 Immune Responses by Murine Langerhans Cells

(2015) Marija Zaric et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Core-crosslinked polymeric micelles: Principles, preparation, biomedical applications and clinical translation

(2015) Marina Talelli et al.   Nano Today

Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine

(2015) Elise Lepeltier et al.   Nanomedicine

Mannan Derivatives Instruct Dendritic Cells to Induce Th1/Th2 Cells Polarization via Differential Mitogen-Activated Protein Kinase Activation

(2015) C. Tong et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Macrophage-Targeting Gene Delivery Using a Micelle Composed of Mannose-Modified Lipid with Triazole Ring and Dioleoyl Trimethylammonium Propane

(2015) Ichiki Fukuda et al.   Biomed Research International

Mechanisms and pathways of innate immune activation and regulation in health and cancer

(2015) Jun Cui et al.   Human Vaccines & Immunotherapeutics

Nanoparticle-Based Immunotherapy for Cancer

(2014) Kun Shao et al.   ACS Nano

Cutting Edge: New Chimeric NOD2/TLR2 Adjuvant Drastically Increases Vaccine Immunogenicity

(2014) Vincent Pavot et al.   JOURNAL OF IMMUNOLOGY

New Perspectives of HPMA-based Copolymers Derived by Post-Polymerization Modification

(2014) Lutz Nuhn et al.   MACROMOLECULAR BIOSCIENCE

Toward Anticancer Immunotherapeutics: Well-Defined Polymer-Antibody Conjugates for Selective Dendritic Cell Targeting

(2014) Kristof Tappertzhofen et al.   MACROMOLECULAR BIOSCIENCE

A Deeper Insight into the Postpolymerization Modification of Polypenta Fluorophenyl Methacrylates to Poly(N-(2-Hydroxypropyl) Methacrylamide)

(2014) Nicole Mohr et al.   MACROMOLECULAR RAPID COMMUNICATIONS

The immune system likes nanotechnology

(2014) Istvan Toth et al.   Nanomedicine

A stable nanoparticulate DDA/MMG formulation acts synergistically with CpG ODN 1826 to enhance the CD4+ T-cell response

(2014) Kasper Karlsen et al.   Nanomedicine

Enhanced Cross-Presentation and Improved CD8+ T Cell Responses after Mannosylation of Synthetic Long Peptides in Mice

(2014) Judith Rauen et al.   PLoS One

CpG-Loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines

(2014) Sebastian Hartmann et al.   Advanced Healthcare Materials

Water-Soluble Polymers Coupled with Glycopeptide Antigens and T-Cell Epitopes as Potential Antitumor Vaccines

(2013) Lutz Nuhn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Adjuvanting Synthetic Antitumor Vaccines from MUC1 Glycopeptides Conjugated to T-Cell Epitopes from Tetanus Toxoid

(2013) Hui Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo : A quantitative study using radiolabeling and positron emission tomography

(2013) Mareli Allmeroth et al.   JOURNAL OF CONTROLLED RELEASE

Encapsulation of Nod1 and Nod2 receptor ligands into poly(lactic acid) nanoparticles potentiates their immune properties

(2013) Vincent Pavot et al.   JOURNAL OF CONTROLLED RELEASE

Interaction of pHPMA–pLMA Copolymers with Human Blood Serum and Its Components

(2013) Mirjam Hemmelmann et al.   MOLECULAR PHARMACEUTICS

Recent advances in glycopolypeptide synthesis

(2013) Jessica R. Kramer et al.   Polymer Chemistry

Sequence-Defined Glycopolymer Segments Presenting Mannose: Synthesis and Lectin Binding Affinity

(2012) Daniela Ponader et al.   BIOMACROMOLECULES

Tailoring the immune response by targeting C-type lectin receptors on alveolar macrophages using “pathogen-like” amphiphilic polyanhydride nanoparticles

(2012) Ana V. Chavez-Santoscoy et al.   BIOMATERIALS

Self-assembly of block copolymers

(2012) Yiyong Mai et al.   CHEMICAL SOCIETY REVIEWS

Biomedical Detection via Macro- and Nano-Sensors Fabricated with Metallic and Semiconducting Oxides

(2012) Jong-In Hahm   Journal of Biomedical Nanotechnology

The mannose receptor

(2012) Luisa Martinez-Pomares   JOURNAL OF LEUKOCYTE BIOLOGY

Allosteric, Chelate, and Interannular Cooperativity: A Mise au Point

(2011) Gianfranco Ercolani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modifying the Body Distribution of HPMA-Based Copolymers by Molecular Weight and Aggregate Formation

(2011) Mareli Allmeroth et al.   BIOMACROMOLECULES

Multivalent Presentation of Mannose on Hyperbranched Polyglycerol and their Interaction with Concanavalin A Lectin

(2011) Ilona Papp et al.   CHEMBIOCHEM

HPMA Based Amphiphilic Copolymers Mediate Central Nervous Effects of Domperidone

(2011) Mirjam Hemmelmann et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Mannose-Functionalized “Pathogen-like” Polyanhydride Nanoparticles Target C-Type Lectin Receptors on Dendritic Cells

(2011) Brenda Carrillo-Conde et al.   MOLECULAR PHARMACEUTICS

Analgesic effects of chemically synthesized NOD1 and NOD2 agonists in mice

(2010) Tadasu Sato et al.   Innate Immunity

TLR-signaling Networks

(2010) J. Brown et al.   JOURNAL OF DENTAL RESEARCH

Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy

(2010) Mathias Krummen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Synthesis of glycopolymers and their multivalent recognitions with lectins

(2010) S. R. Simon Ting et al.   Polymer Chemistry

A spoonful of sugar: the application of glycopolymers in therapeutics

(2010) Sebastian G. Spain et al.   Polymer Chemistry

HPMA copolymers: Origins, early developments, present, and future☆

(2009) Jindřich Kopeček et al.   ADVANCED DRUG DELIVERY REVIEWS

Do HPMA copolymer conjugates have a future as clinically useful nanomedicines? A critical overview of current status and future opportunities☆

(2009) Ruth Duncan et al.   ADVANCED DRUG DELIVERY REVIEWS

The uptake of N-(2-hydroxypropyl)-methacrylamide based homo, random and block copolymers by human multi-drug resistant breast adenocarcinoma cells

(2009) Matthias Barz et al.   BIOMATERIALS

Postpolymerization modification of poly(pentafluorophenyl methacrylate): Synthesis of a diverse water-soluble polymer library

(2009) Matthew I. Gibson et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Dendritic Cells as Danger-Recognizing Biosensors

(2009) Mia Gi et al.   SENSORS

Vesicular Stomatitis Virus Enters Cells through Vesicles Incompletely Coated with Clathrin That Depend upon Actin for Internalization

(2009) David K. Cureton et al.   PLoS Pathogens

From Defined Reactive Diblock Copolymers to Functional HPMA-Based Self-Assembled Nanoaggregates

(2008) M. Barz et al.   BIOMACROMOLECULES

Mannose-targeted systems for the delivery of therapeutics

(2008) Juan M Irache et al.   Expert Opinion on Drug Delivery

Radical addition–fragmentation chemistry in polymer synthesis

(2007) Graeme Moad et al.   POLYMER