Pathogenicity and virulence of Borrelia burgdorferi

A putative xanthine dehydrogenase is critical for Borrelia burgdorferi survival in ticks and mice

(2023) James P. Phelan et al.   MICROBIOLOGY-SGM

DNA lipid nanoparticle vaccine targeting outer surface protein C affords protection against homologous Borrelia burgdorferi needle challenge in mice

(2023) Annabelle Pfeifle et al.   Frontiers in Immunology

Choreography of Lyme Disease Spirochete Adhesins To Promote Vascular Escape

(2023) Xi Tan et al.   Microbiology Spectrum

Safety and immunogenicity of a novel multivalent OspA-based vaccine candidate against Lyme borreliosis: a randomised, phase 1 study in healthy adults

(2023) Nicole Bézay et al.   LANCET INFECTIOUS DISEASES

Introduction of IgM testing for the diagnosis of acute Lyme borreliosis: a study of the benefits, limitations and costs

(2022) Greg Joyner et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Borrelia burgdorferi Outer Membrane Vesicles Contain Antigenic Proteins, but Do Not Induce Cell Death in Human Cells

(2022) Kati Karvonen et al.   Microorganisms

The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick

(2022) Dan Drecktrah et al.   PLoS Pathogens

VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force

(2022) Xi Tan et al.   PLoS Pathogens

Borrelia burgdorferi inhibits NADPH-mediated reactive oxygen species production through the mTOR pathway

(2022) Mariska Kerstholt et al.   Ticks and Tick-Borne Diseases

Borrelia burgdorferi modulates the physical forces and immunity signaling in endothelial cells

(2022) Raúl Aparicio Yuste et al.   iScience

Clinical Evaluation of a Borrelia Modified Two-Tiered Testing (MTTT) Shows Increased Early Sensitivity for Borrelia burgdorferi But Not Other Endemic Borrelia Species in A High Incidence Region for Lyme Disease in Wisconsin

(2022) Arick P. Sabin et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

No correlation between symptom duration and intrathecal production of IgM and/or IgG antibodies in Lyme neuroborreliosis – a retrospective cohort study in Denmark

(2022) Ingrid Krogen et al.   JOURNAL OF INFECTION

Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle

(2021) Ashley M. Groshong et al.   PLoS Pathogens

Laboratory Diagnosis of Lyme Borreliosis

(2021) John A. Branda et al.   CLINICAL MICROBIOLOGY REVIEWS

Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis

(2021) M. J. Klouwens et al.   Scientific Reports

Tick-Tattoo: DNA Vaccination Against B. burgdorferi or Ixodes scapularis Tick Proteins

(2021) Michelle J. Klouwens et al.   Frontiers in Immunology

Tick Immune System: What Is Known, the Interconnections, the Gaps, and the Challenges

(2021) Andréa C. Fogaça et al.   Frontiers in Immunology

Nanomechanical mechanisms of Lyme disease spirochete motility enhancement in extracellular matrix

(2021) Martin Strnad et al.   Communications Biology

The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete

(2021) Marisela M. Davis et al.   PLoS Pathogens

Borrelia peptidoglycan interacting Protein (BpiP) contributes to the fitness of Borrelia burgdorferi against host-derived factors and influences virulence in mouse models of Lyme disease

(2021) Yue Chen et al.   PLoS Pathogens

Resonance assignment and secondary structure of DbpA protein from the European species, Borrelia afzelii

(2021) Libor Hejduk et al.   Biomolecular NMR Assignments

PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi

(2021) Ashley M. Groshong et al.   PLoS Pathogens

BB0562 is a nutritional virulence determinant with lipase activity important for Borrelia burgdorferi infection and survival in fatty acid deficient environments

(2021) Hunter W. Kuhn et al.   PLoS Pathogens

The Borrelia burgdorferi Adenylate Cyclase, CyaB, Is Important for Virulence Factor Production and Mammalian Infection

(2021) Vanessa M. Ante et al.   Frontiers in Microbiology

Recent Progress in Lyme Disease and Remaining Challenges

(2021) Jason R. Bobe et al.   Frontiers in Medicine

Tick-transmitted co-infections among erythema migrans patients in a general practice setting in Norway: a clinical and laboratory follow-up study

(2021) Knut Eirik Eliassen et al.   BMC INFECTIOUS DISEASES

A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist

(2021) Katelyn H. Wong et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Distinctive Evasion Mechanisms to Allow Persistence of Borrelia burgdorferi in Different Human Cell Lines

(2021) Kati Karvonen et al.   Frontiers in Microbiology

The unusual cell wall of the Lyme disease spirochaete Borrelia burgdorferi is shaped by a tick sugar

(2021) Tanner G. DeHart et al.   Nature Microbiology

Novel targets and strategies to combat borreliosis

(2020) Martin Strnad et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A broadly protective multivalent OspA vaccine based on surface shaping of the C-terminal fragment

(2020) Abhijeet Nayak et al.   INFECTION AND IMMUNITY

The need to unravel the twisted nature of the Borrelia burgdorferi sensu lato complex across Europe

(2020) Martin Strnad et al.   MICROBIOLOGY-SGM

Borrelia burgdorferi hijacks cellular metabolism of immune cells: Consequences for host defense

(2020) Mariska Kerstholt et al.   Ticks and Tick-Borne Diseases

Three-dimensional reconstruction of the feeding apparatus of the tick Ixodes ricinus (Acari: Ixodidae): a new insight into the mechanism of blood-feeding

(2020) Marie Vancová et al.   Scientific Reports

Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt- and Mutant CFTR

(2020) Ana P. Carapeto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Performance of a Modified Two-Tiered Testing (MTTT) EIA Algorithm for Serologic Diagnosis of Lyme Disease in Nova Scotia

(2020) Ian R. C. Davis et al.   JOURNAL OF CLINICAL MICROBIOLOGY

DksA plays an essential role in regulating the virulence of Borrelia burgdorferi

(2020) Charlotte Mason et al.   MOLECULAR MICROBIOLOGY

Rapid clearance of Borrelia burgdorferi from the blood circulation

(2020) Liucun Liang et al.   Parasites & Vectors

Complement Evasion by Lyme Disease Spirochetes

(2020) Jon T. Skare et al.   TRENDS IN MICROBIOLOGY

Complement Evasion Contributes to Lyme Borreliae–Host Associations

(2020) Yi-Pin Lin et al.   TRENDS IN PARASITOLOGY

The Borrelia burgdorferi VlsE Lipoprotein Prevents Antibody Binding to an Arthritis-Related Surface Antigen

(2020) Abdul G. Lone et al.   Cell Reports

Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C

(2020) Yi-Pin Lin et al.   PLoS Pathogens

Design of a broadly reactive Lyme disease vaccine

(2020) Heather D. Kamp et al.   npj Vaccines

Diagnostic parameters of modified two-tier testing in European patients with early Lyme disease

(2020) ME Baarsma et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Interactions between Borrelia burgdorferi and ticks

(2020) Cheyne Kurokawa et al.   NATURE REVIEWS MICROBIOLOGY

Ex Vivo Murine Skin Model for B. burgdorferi Biofilm

(2020) Jason P. Torres et al.   Antibiotics-Basel

FIB/SEM-based analysis of Borrelia intracellular processing by human macrophages

(2020) Matthias Klose et al.   JOURNAL OF CELL SCIENCE

Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease

(2020) Paul M. Lantos et al.   ARTHRITIS CARE & RESEARCH

Hedgehogs, Squirrels, and Blackbirds as Sentinel Hosts for Active Surveillance of Borrelia miyamotoi and Borrelia burgdorferi Complex in Urban and Rural Environments

(2020) Karolina Majerová et al.   Microorganisms

Strong interactions between Salp15 homologues from the tick I. ricinus and distinct types of the outer surface OspC protein from Borrelia

(2020) Paulina Bierwagen et al.   Ticks and Tick-Borne Diseases

Lyme Disease Pathogenesis

(2020) Jenifer Coburn et al.   CURRENT ISSUES IN MOLECULAR BIOLOGY

Genetic Manipulation of Borrelia

(2020) Patricia A. Rosa et al.   CURRENT ISSUES IN MOLECULAR BIOLOGY

The AI-2/luxS Quorum Sensing System Affects the Growth Characteristics, Biofilm Formation, and Virulence of Haemophilus parasuis

(2019) Bingzhou Zhang et al.   Frontiers in Cellular and Infection Microbiology

How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication

(2019) Wolfgang Eisenreich et al.   Frontiers in Cellular and Infection Microbiology

Tracking of Borrelia afzelii transmission from infected Ixodes ricinus nymphs to mice

(2019) Tereza Pospisilova et al.   INFECTION AND IMMUNITY

Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission

(2019) Ryan O. M. Rego et al.   Parasites & Vectors

Tick-borne pathogen detection in midgut and salivary glands of adult Ixodes ricinus

(2019) Emilie Lejal et al.   Parasites & Vectors

Metamorphoses of Lyme disease spirochetes: phenomenon of Borrelia persisters

(2019) Natalie Rudenko et al.   Parasites & Vectors

Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis

(2019) Brandon L. Jutras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hijacking the Supplies: Metabolism as a Novel Facet of Virus-Host Interaction

(2019) Katharina A. Mayer et al.   Frontiers in Immunology

Inner Workings: Lyme disease vaccines face familiar challenges, both societal and scientific

(2019) Leah Shaffer   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Borrelia burgdorferi chemotaxis toward tick protein Salp12 contributes to acquisition

(2019) Kristen E. Murfin et al.   Ticks and Tick-Borne Diseases

Visualization of Spirochetes by Labeling Membrane Proteins With Fluorescent Biarsenical Dyes

(2019) Chadwick Hillman et al.   Frontiers in Cellular and Infection Microbiology

Structural conservation and diversity of PilZ-related domains

(2019) Michael Y. Galperin et al.   JOURNAL OF BACTERIOLOGY

A Novel Laminin-Binding Protein Mediates Microbial-Endothelial Cell Interactions and Facilitates Dissemination of Lyme Disease Pathogens

(2019) Sandhya Bista et al.   JOURNAL OF INFECTIOUS DISEASES

Late Disseminated Lyme Disease

(2018) Nicholas A. Crossland et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of glutathione metabolism in host defense againstBorrelia burgdorferiinfection

(2018) Mariska Kerstholt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigenic Variation in the Lyme Spirochete: Insights into Recombinational Switching with a Suggested Role for Error-Prone Repair

(2018) Theodore B. Verhey et al.   Cell Reports

The Propensity of Different Borrelia burgdorferi sensu stricto Genotypes to Cause Disseminated Infections in Humans

(2018) Daniel E. Dykhuizen et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

DksA controls the response of the Lyme disease spirochete Borrelia burgdorferi to starvation

(2018) William K. Boyle et al.   JOURNAL OF BACTERIOLOGY

A bite so sweet: the glycobiology interface of tick-host-pathogen interactions

(2018) Pavlina Vechtova et al.   Parasites & Vectors

Published data do not support the notion that Borrelia valaisiana is human pathogenic

(2017) Gabriele Margos et al.   INFECTION

Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial Surface

(2017) Alexander S. Dowdell et al.   JOURNAL OF BACTERIOLOGY

Borrelia burgdorferi BBI39 Paralogs, Targets of Protective Immunity, Reduce Pathogen Persistence Either in Hosts or in the Vector

(2017) Preeti Singh et al.   JOURNAL OF INFECTIOUS DISEASES

Plasma fibronectin stabilizesBorrelia burgdorferi–endothelial interactions under vascular shear stress by a catch-bond mechanism

(2017) Alexandra F. Niddam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species

(2017) Meghan E. Ramsey et al.   PLoS Pathogens

Pleomorphism and Viability of the Lyme Disease Pathogen Borrelia burgdorferi Exposed to Physiological Stress Conditions: A Correlative Cryo-Fluorescence and Cryo-Scanning Electron Microscopy Study

(2017) Marie Vancová et al.   Frontiers in Microbiology

Outer Membrane Vesicles (OMVs) of Gram-negative Bacteria: A Perspective Update

(2017) Arif Tasleem Jan   Frontiers in Microbiology

Borrelia burgdorferi Keeps Moving and Carries on: A Review of Borrelial Dissemination and Invasion

(2017) Jenny A. Hyde   Frontiers in Immunology

Borrelia burgdorferi Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts

(2017) Karen E. Tracy et al.   Frontiers in Immunology

The Accuracy of Diagnostic Tests for Lyme Disease in Humans, A Systematic Review and Meta-Analysis of North American Research

(2017) Lisa A. Waddell et al.   PLoS One

Whole Genome Sequence and Comparative Genomics of the Novel Lyme Borreliosis Causing Pathogen, Borrelia mayonii

(2017) Luke C. Kingry et al.   PLoS One

The novel Lyme borreliosis vaccine VLA15 shows broad protection against Borrelia species expressing six different OspA serotypes

(2017) Pär Comstedt et al.   PLoS One

Borrelia bissettiae sp. nov. and Borrelia californiensis sp. nov. prevail in diverse enzootic transmission cycles

(2016) Gabriele Margos et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Flow-Tolerant Adhesion of a Bacterial Pathogen to Human Endothelial Cells Through Interaction With Biglycan

(2016) Jemiina Salo et al.   JOURNAL OF INFECTIOUS DISEASES

Pleomorphic forms of Borrelia burgdorferi induce distinct immune responses

(2016) Leena Meriläinen et al.   MICROBES AND INFECTION

Bacterial outer membrane vesicles: New insights and applications

(2016) Deepak Anand et al.   MOLECULAR MEMBRANE BIOLOGY

Larvae of Ixodes ricinus transmit Borrelia afzelii and B. miyamotoi to vertebrate hosts

(2016) Gilian van Duijvendijk et al.   Parasites & Vectors

Biomechanics of Borrelia burgdorferi Vascular Interactions

(2016) Rhodaba Ebady et al.   Cell Reports

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

(2016) Brandon L. Garcia et al.   PLoS Pathogens

Sequestration of host metabolism by an intracellular pathogen

(2016) Lena Gehre et al.   eLife

Lyme borreliosis

(2016) Allen C. Steere et al.   Nature Reviews Disease Primers

RNA-Seq of Borrelia burgdorferi in Multiple Phases of Growth Reveals Insights into the Dynamics of Gene Expression, Transcriptome Architecture, and Noncoding RNAs

(2016) William K. Arnold et al.   PLoS One

Integrin binding byBorrelia burgdorferi P66 facilitates dissemination but is not required for infectivity

(2015) Laura C. Ristow et al.   CELLULAR MICROBIOLOGY

Glycosaminoglycan binding byBorrelia burgdorferiadhesin BBK32 specifically and uniquely promotes joint colonization

(2015) Yi-Pin Lin et al.   CELLULAR MICROBIOLOGY

Middle region of theBorrelia burgdorferisurface-located protein 1 (Lmp1) interacts with host chondroitin-6-sulfate and independently facilitates infection

(2015) Xiuli Yang et al.   CELLULAR MICROBIOLOGY

A Dutch nationwide evaluation of serological assays for detection of Borrelia antibodies in clinically well-defined patients

(2015) C.W. Ang et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Molecular Dissection of a Borrelia burgdorferiIn VivoEssential Purine Transport System

(2015) Sunny Jain et al.   INFECTION AND IMMUNITY

A Short-Term Borrelia burgdorferi Infection Model Identifies Tissue Tropisms and Bloodstream Survival Conferred by Adhesion Proteins

(2015) Jennifer A. Caine et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi RevA Significantly Affects Pathogenicity and Host Response in the Mouse Model of Lyme Disease

(2015) Rebecca Byram et al.   INFECTION AND IMMUNITY

Apparent Role for Borrelia burgdorferi LuxS during Mammalian Infection

(2015) William K. Arnold et al.   INFECTION AND IMMUNITY

Outer Surface Protein OspC Is an Antiphagocytic Factor That Protects Borrelia burgdorferi from Phagocytosis by Macrophages

(2015) Sebastian E. Carrasco et al.   INFECTION AND IMMUNITY

Ixodes scapularis dystroglycan-like protein promotes Borrelia burgdorferi migration from the gut

(2015) Jeroen Coumou et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Use of in vivo Expression Technology for the Identification of Putative Host Adaptation Factors of the Lyme Disease Spirochete

(2015) Timothy Casselli et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Modulation of host immunity by tick saliva

(2015) Jan Kotál et al.   Journal of Proteomics

Morphological and biochemical features of Borrelia burgdorferi pleomorphic forms

(2015) Leena Meriläinen et al.   MICROBIOLOGY-SGM

The BBA33 lipoprotein binds collagen and impactsBorrelia burgdorferipathogenesis

(2015) Hui Zhi et al.   MOLECULAR MICROBIOLOGY

BGA66 and BGA71 facilitate complement resistance ofBorrelia bavariensisby inhibiting assembly of the membrane attack complex

(2015) Claudia Hammerschmidt et al.   MOLECULAR MICROBIOLOGY

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

(2015) Tiago R. D. Costa et al.   NATURE REVIEWS MICROBIOLOGY

Search for blood or water is influenced by Borrelia burgdorferi in Ixodes ricinus

(2015) Coralie Herrmann et al.   Parasites & Vectors

Correlative cryo-fluorescence and cryo-scanning electron microscopy as a straightforward tool to study host-pathogen interactions

(2015) Martin Strnad et al.   Scientific Reports

Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein

(2015) Devender Kumar et al.   PLoS Pathogens

Decorin Binding Proteins of Borrelia burgdorferi Promote Arthritis Development and Joint Specific Post-Treatment DNA Persistence in Mice

(2015) Jemiina Salo et al.   PLoS One

Complete Genome Sequence of Borrelia afzelii K78 and Comparative Genome Analysis

(2015) Wolfgang Schüler et al.   PLoS One

Gut Microbiota of the Tick Vector Ixodes scapularis Modulate Colonization of the Lyme Disease Spirochete

(2014) Sukanya Narasimhan et al.   Cell Host & Microbe

Rapid outer-surface protein C DNA tattoo vaccination protects against Borrelia afzelii infection

(2014) A Wagemakers et al.   GENE THERAPY

Defensins from the tick Ixodes scapularis are effective against phytopathogenic fungi and the human bacterial pathogen Listeria grayi

(2014) Miray Tonk et al.   Parasites & Vectors

Surface attachment inducesPseudomonas aeruginosavirulence

(2014) Albert Siryaporn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Tick Gut Protein with Fibronectin III Domains Aids Borrelia burgdorferi Congregation to the Gut during Transmission

(2014) Sukanya Narasimhan et al.   PLoS Pathogens

Strain-Specific Variation of the Decorin-Binding Adhesin DbpA Influences the Tissue Tropism of the Lyme Disease Spirochete

(2014) Yi-Pin Lin et al.   PLoS Pathogens

A Systematic Review of Borrelia burgdorferi Morphologic Variants Does Not Support a Role in Chronic Lyme Disease

(2013) P. M. Lantos et al.   CLINICAL INFECTIOUS DISEASES

Motility Is Crucial for the Infectious Life Cycle of Borrelia burgdorferi

(2013) Syed Z. Sultan et al.   INFECTION AND IMMUNITY

Versatile Roles of CspA Orthologs in Complement Inactivation of Serum-Resistant Lyme Disease Spirochetes

(2013) Claudia Hammerschmidt et al.   INFECTION AND IMMUNITY

The Early Dissemination Defect Attributed to Disruption of Decorin-Binding Proteins Is Abolished in Chronic Murine Lyme Borreliosis

(2013) Denise M. Imai et al.   INFECTION AND IMMUNITY

Lyme Borreliosis in Human Patients in Florida and Georgia, USA

(2013) Kerry L. Clark et al.   International Journal of Medical Sciences

BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin  3 1

(2013) E. Wood et al.   JOURNAL OF BACTERIOLOGY

BBA70 ofBorrelia burgdorferiIs a Novel Plasminogen-binding Protein

(2013) Arno Koenigs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Safety and immunogenicity of a novel multivalent OspA vaccine against Lyme borreliosis in healthy adults: a double-blind, randomised, dose-escalation phase 1/2 trial

(2013) Nina Wressnigg et al.   LANCET INFECTIOUS DISEASES

The HtrA protease ofBorrelia burgdorferidegrades outer membrane protein BmpD and chemotaxis phosphatase CheX

(2013) James L. Coleman et al.   MOLECULAR MICROBIOLOGY

Lipoprotein succession inBorrelia burgdorferi: similar but distinct roles for OspC and VlsE at different stages of mammalian infection

(2013) Kit Tilly et al.   MOLECULAR MICROBIOLOGY

BB0347, from the Lyme Disease Spirochete Borrelia burgdorferi, Is Surface Exposed and Interacts with the CS1 Heparin-Binding Domain of Human Fibronectin

(2013) Robert A. Gaultney et al.   PLoS One

Illuminating the roles of the Borrelia burgdorferi adhesins

(2013) Jenifer Coburn et al.   TRENDS IN MICROBIOLOGY

Cyclic di-GMP mediates Mycobacterium tuberculosis dormancy and pathogenecity

(2013) Yuzhi Hong et al.   TUBERCULOSIS

CspA from Borrelia burgdorferi Inhibits the Terminal Complement Pathway

(2013) T. Hallstrom et al.   mBio

In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in Mice

(2013) Tisha Choudhury Ellis et al.   PLoS Pathogens

Lipid Exchange between Borrelia burgdorferi and Host Cells

(2013) Jameson T. Crowley et al.   PLoS Pathogens

Detection of Borrelia burgdorferi Sensu StrictoospCAlleles Associated with Human Lyme Borreliosis Worldwide in Non-Human-Biting Tick Ixodes affinis and Rodent Hosts in Southeastern United States

(2012) Nataliia Rudenko et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Solution Structure of Decorin-Binding Protein A from Borrelia burgdorferi

(2012) Xu Wang   BIOCHEMISTRY

Technologies for enhanced efficacy of DNA vaccines

(2012) Fadi Saade et al.   Expert Review of Vaccines

Borrelia burgdorferi malQmutants utilize disaccharides and traverse the enzootic cycle

(2012) Laura L. Hoon-Hanks et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

OspC Is Potent Plasminogen Receptor on Surface ofBorrelia burgdorferi

(2012) Özlem Önder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasminogen Is a Complement Inhibitor

(2012) Diana Barthel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules

(2012) Tara J. Moriarty et al.   MOLECULAR MICROBIOLOGY

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

(2012) Justin D. Radolf et al.   NATURE REVIEWS MICROBIOLOGY

Cell Elasticity Determines Macrophage Function

(2012) Naimish R. Patel et al.   PLoS One

Characterization of Biofilm Formation by Borrelia burgdorferi In Vitro

(2012) Eva Sapi et al.   PLoS One

Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity

(2012) Tao Lin et al.   PLoS One

The heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue

(2012) M. W. Harman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Borrelia burgdorferi Requires the Alternative Sigma Factor RpoS for Dissemination within the Vector during Tick-to-Mammal Transmission

(2012) Star M. Dunham-Ems et al.   PLoS Pathogens

Allelic Variation of the Lyme Disease Spirochete Adhesin DbpA Influences Spirochetal Binding to Decorin, Dermatan Sulfate, and Mammalian Cells

(2011) Vivian M. Benoit et al.   INFECTION AND IMMUNITY

Whole-Genome Sequences of Two Borrelia afzelii and Two Borrelia garinii Lyme Disease Agent Isolates

(2011) S. R. Casjens et al.   JOURNAL OF BACTERIOLOGY

Whole-Genome Sequences of Borrelia bissettii, Borrelia valaisiana, and Borrelia spielmanii

(2011) S. E. Schutzer et al.   JOURNAL OF BACTERIOLOGY

Decorin Binding by DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi Sensu Stricto

(2011) Jemiina Salo et al.   JOURNAL OF INFECTIOUS DISEASES

Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa

(2011) Hüsnü Topal et al.   JOURNAL OF MOLECULAR BIOLOGY

The BB0646 protein demonstrates lipase and haemolytic activity associated with Borrelia burgdorferi, the aetiological agent of Lyme disease

(2011) Dana K. Shaw et al.   MOLECULAR MICROBIOLOGY

Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity

(2011) Jenny A. Hyde et al.   MOLECULAR MICROBIOLOGY

Outer Surface Protein C Is a Dissemination-Facilitating Factor of Borrelia burgdorferi during Mammalian Infection

(2011) Sunita V. Seemanapalli et al.   PLoS One

Biodiversity of Borrelia burgdorferi Strains in Tissues of Lyme Disease Patients

(2011) Dustin Brisson et al.   PLoS One

Borrelia burgdorferi BBA52 is a potential target for transmission blocking Lyme disease vaccine

(2011) Manish Kumar et al.   VACCINE

Updates on Borrelia burgdorferi sensu lato complex with respect to public health

(2011) Nataliia Rudenko et al.   Ticks and Tick-Borne Diseases

Borrelia burgdorferi Requires Glycerol for Maximum Fitness During The Tick Phase of the Enzootic Cycle

(2011) Christopher J. Pappas et al.   PLoS Pathogens

Molecular Interactions that Enable Movement of the Lyme Disease Agent from the Tick Gut into the Hemolymph

(2011) Lili Zhang et al.   PLoS Pathogens

Cholesterol Lipids of Borrelia burgdorferi Form Lipid Rafts and Are Required for the Bactericidal Activity of a Complement-Independent Antibody

(2010) Timothy J. LaRocca et al.   Cell Host & Microbe

Lyme borreliosis: Clinical case definitions for diagnosis and management in Europe

(2010) G. Stanek et al.   CLINICAL MICROBIOLOGY AND INFECTION

Invasion of Eukaryotic Cells byBorrelia burgdorferiRequires β1Integrins and Src Kinase Activity

(2010) Jing Wu et al.   INFECTION AND IMMUNITY

BBA52 FacilitatesBorrelia burgdorferiTransmission from Feeding Ticks to Murine Hosts

(2010) Manish Kumar et al.   JOURNAL OF INFECTIOUS DISEASES

Complement Regulator–Acquiring Surface Protein 1 ofBorrelia burgdorferiBinds to Human Bone Morphogenic Protein 2, Several Extracellular Matrix Proteins, and Plasminogen

(2010) Teresia Hallström et al.   JOURNAL OF INFECTIOUS DISEASES

Inactivation of a putative flagellar motor switch protein FliG1 preventsBorrelia burgdorferifrom swimming in highly viscous media and blocks its infectivity

(2010) Chunhao Li et al.   MOLECULAR MICROBIOLOGY

Characterization of proteinases from the midgut of Rhipicephalus (Boophilus) microplus involved in the generation of antimicrobial peptides

(2010) Carlos E Cruz et al.   Parasites & Vectors

The identification and characterization of lysozyme from the hard tick Haemaphysalis longicornis

(2010) Tetsuya Tanaka et al.   Ticks and Tick-Borne Diseases

Role ofluxSinBacillus anthracisgrowth and virulence factor expression

(2010) Marcus B. Jones et al.   Virulence

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

Comprehensive seroprofiling of sixteen B. burgdorferi OspC: Implications for Lyme disease diagnostics design

(2009) Larisa Ivanova et al.   CLINICAL IMMUNOLOGY

Molecular detection ofBorrelia bissettiiDNA in serum samples from patients in the Czech Republic with suspected borreliosis

(2009) Nataliia Rudenko et al.   FEMS MICROBIOLOGY LETTERS

Borrelia burgdorferi RevA Antigen Binds Host Fibronectin

(2009) C. A. Brissette et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi BmpA Is a Laminin-Binding Protein

(2009) A. Verma et al.   INFECTION AND IMMUNITY

Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks

(2009) Star M. Dunham-Ems et al.   JOURNAL OF CLINICAL INVESTIGATION

The Borrelia burgdorferi outer-surface protein ErpX binds mammalian laminin

(2009) C. A. Brissette et al.   MICROBIOLOGY-SGM

Comparative cryo-electron tomography of pathogenic Lyme disease spirochetes

(2009) Mikhail Kudryashev et al.   MOLECULAR MICROBIOLOGY

A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi

(2009) Z. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detailed Analysis of Sequence Changes Occurring during vlsE Antigenic Variation in the Mouse Model of Borrelia burgdorferi Infection

(2009) Loïc Coutte et al.   PLoS Pathogens

Central Role of the Holliday Junction Helicase RuvAB in vlsE Recombination and Infectivity of Borrelia burgdorferi

(2009) Tao Lin et al.   PLoS Pathogens

Borrelia burgdorferi Infection-Associated Surface Proteins ErpP, ErpA, and ErpC Bind Human Plasminogen

(2008) C. A. Brissette et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi Lacking DbpBA Exhibits an Early Survival Defect during Experimental Infection

(2008) E. H. Weening et al.   INFECTION AND IMMUNITY

Both Decorin-Binding Proteins A and B Are Critical for the Overall Virulence of Borrelia burgdorferi

(2008) Y. Shi et al.   INFECTION AND IMMUNITY

Biology of Infection with Borrelia burgdorferi

(2008) Kit Tilly et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

FHR-1, an additional human plasma protein, binds to complement regulator-acquiring surface proteins of Borrelia burgdorferi

(2008) Katrin Haupt et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Detection of Borrelia bissettii in Cardiac Valve Tissue of a Patient with Endocarditis and Aortic Valve Stenosis in the Czech Republic

(2008) N. Rudenko et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Preferential Protection ofBorrelia burgdorferiSensu Stricto by a Salp15 Homologue inIxodes ricinusSaliva

(2008) J. W. Hovius et al.   JOURNAL OF INFECTIOUS DISEASES

Essential protective role attributed to the surface lipoproteins ofBorrelia burgdorferiagainst innate defences

(2008) Qilong Xu et al.   MOLECULAR MICROBIOLOGY

Borrelia burgdorferi membranes are the primary targets of reactive oxygen species

(2008) Julie A. Boylan et al.   MOLECULAR MICROBIOLOGY

sodAis essential for virulence ofBorrelia burgdorferiin the murine model of Lyme disease

(2008) Maria D. Esteve-Gassent et al.   MOLECULAR MICROBIOLOGY

Carbon catabolite repression in bacteria: many ways to make the most out of nutrients

(2008) Boris Görke et al.   NATURE REVIEWS MICROBIOLOGY

Molecular Mechanisms Involved in Vascular Interactions of the Lyme Disease Pathogen in a Living Host

(2008) M. Ursula Norman et al.   PLoS Pathogens

Real-Time High Resolution 3D Imaging of the Lyme Disease Spirochete Adhering to and Escaping from the Vasculature of a Living Host

(2008) Tara J. Moriarty et al.   PLoS Pathogens