Analysis of metabolites in human gut: illuminating the design of gut-targeted drugs
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Analysis of metabolites in human gut: illuminating the design of gut-targeted drugs
Authors
Keywords
-
Journal
Journal of Cheminformatics
Volume 15, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-13
DOI
10.1186/s13321-023-00768-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Review on the Recent Applications of Deep Learning in Predictive Drug Toxicological Studies
- (2023) Krishnendu Sinha et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Recent Advances in Machine-Learning-Based Chemoinformatics: A Comprehensive Review
- (2023) Sarfaraz K. Niazi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Emerging targetome and signalome landscape of gut microbial metabolites
- (2022) Xiao Zheng et al. Cell Metabolism
- Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice
- (2022) Aneta Grycová et al. JOURNAL OF MEDICINAL CHEMISTRY
- Systematic Analysis and Prediction of the Target Space of Bioactive Food Compounds: Filling the Chemobiological Gaps
- (2022) Andrés Sánchez-Ruiz et al. Journal of Chemical Information and Modeling
- Machine intelligence-driven framework for optimized hit selection in virtual screening
- (2022) Neeraj Kumar et al. Journal of Cheminformatics
- Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
- (2022) Zdenek Dvorak et al. DRUG METABOLISM AND DISPOSITION
- Deep learning methods for molecular representation and property prediction
- (2022) Zhen Li et al. DRUG DISCOVERY TODAY
- Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics
- (2022) Laura E. McCoubrey et al. JOURNAL OF CONTROLLED RELEASE
- Expanding the drug discovery space with predicted metabolite–target interactions
- (2021) Andrea Nuzzo et al. Communications Biology
- Clinical translation of advanced colonic drug delivery technologies
- (2021) Atheer Awad et al. ADVANCED DRUG DELIVERY REVIEWS
- Microbial metabolite deoxycholic acid promotes vasculogenic mimicry formation in intestinal carcinogenesis
- (2021) Xueli Song et al. CANCER SCIENCE
- Updated Prediction of Aggregators and Assay-Interfering Substructures in Food Compounds
- (2021) Andrés Sánchez-Ruiz et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- HMDB 5.0: the Human Metabolome Database for 2022
- (2021) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Quantitative Structure-Activity Relationship (QSAR) modeling to predict the transfer of environmental chemicals across the placenta
- (2021) Laura Lévêque et al. Computational Toxicology
- Global chemical effects of the microbiome include new bile-acid conjugations
- (2020) Robert A. Quinn et al. NATURE
- Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
- (2020) Aonghus Lavelle et al. Nature Reviews Gastroenterology & Hepatology
- Targeting the pregnane X receptor using microbial metabolite mimicry
- (2020) Zdeněk Dvořák et al. EMBO Molecular Medicine
- Microbiome Metabolite Mimics Accelerate Drug Discovery
- (2020) Andrea Nuzzo et al. TRENDS IN MOLECULAR MEDICINE
- Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors
- (2020) Susan Hua Frontiers in Pharmacology
- Personalized Mapping of Drug Metabolism by the Human Gut Microbiome
- (2020) Bahar Javdan et al. CELL
- Open access in silico tools to predict the ADMET profiling of drug candidates
- (2020) Supratik Kar et al. Expert Opinion on Drug Discovery
- Analysis of Nuisance Substructures and Aggregators in a Comprehensive Database of Food Chemical Compounds
- (2020) Irem Kaya et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- A metabolic pathway for bile acid dehydroxylation by the gut microbiome
- (2020) Masanori Funabashi et al. NATURE
- Gut microbiota in human metabolic health and disease
- (2020) Yong Fan et al. NATURE REVIEWS MICROBIOLOGY
- An open source chemical structure curation pipeline using RDKit
- (2020) A. Patrícia Bento et al. Journal of Cheminformatics
- Gut microbiota-derived metabolites as central regulators in metabolic disorders
- (2020) Allison Agus et al. GUT
- Deciphering Human Microbiota–Host Chemical Interactions
- (2020) Justin E. Silpe et al. ACS Central Science
- A new genomic blueprint of the human gut microbiota
- (2019) Alexandre Almeida et al. NATURE
- The Integrative Human Microbiome Project
- (2019) NATURE
- The human endogenous metabolome as a pharmacology baseline for drug discovery
- (2019) Andreu Bofill et al. DRUG DISCOVERY TODAY
- Deep Learning for Deep Chemistry: Optimizing the Prediction of Chemical Patterns
- (2019) Tânia F. G. G. Cova et al. Frontiers in Chemistry
- Molecular messages in human microbiota
- (2019) Matthew T. Henke et al. SCIENCE
- The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
- (2018) Christine A. Olson et al. CELL
- Current understanding of the human microbiome
- (2018) Jack A Gilbert et al. NATURE MEDICINE
- Large-scale comparison of machine learning methods for drug target prediction on ChEMBL
- (2018) Andreas Mayr et al. Chemical Science
- Machine learning for molecular and materials science
- (2018) Keith T. Butler et al. NATURE
- In silico ADME-Tox modeling: progress and prospects
- (2017) Saeed Alqahtani Expert Opinion on Drug Metabolism & Toxicology
- DrugBank 5.0: a major update to the DrugBank database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Analysis of drug–endogenous human metabolite similarities in terms of their maximum common substructures
- (2017) Steve O’Hagan et al. Journal of Cheminformatics
- The Intestinal Microbiome in Infectious Diseases: The Clinical Relevance of a Rapidly Emerging Field
- (2017) Vanessa C Harris et al. Open Forum Infectious Diseases
- Fisher’s exact approach for post hoc analysis of a chi-squared test
- (2017) Guogen Shan et al. PLoS One
- Human microbial metabolites as a source of new drugs
- (2016) Somdutta Saha et al. DRUG DISCOVERY TODAY
- ClassyFire: automated chemical classification with a comprehensive, computable taxonomy
- (2016) Yannick Djoumbou Feunang et al. Journal of Cheminformatics
- An analysis of the attrition of drug candidates from four major pharmaceutical companies
- (2015) Michael J. Waring et al. NATURE REVIEWS DRUG DISCOVERY
- Small molecules from the human microbiota
- (2015) M. S. Donia et al. SCIENCE
- Gut microbiome development along the colorectal adenoma–carcinoma sequence
- (2015) Qiang Feng et al. Nature Communications
- A ‘rule of 0.5’ for the metabolite-likeness of approved pharmaceutical drugs
- (2014) Steve O′Hagan et al. Metabolomics
- Gut microbiota–generated metabolites in animal health and disease
- (2014) Won-Jae Lee et al. Nature Chemical Biology
- Support vector machines for drug discovery
- (2013) Kathrin Heikamp et al. Expert Opinion on Drug Discovery
- Quantifying the chemical beauty of drugs
- (2012) G. Richard Bickerton et al. Nature Chemistry
- Targeting gut microbiota in obesity: effects of prebiotics and probiotics
- (2011) Nathalie M. Delzenne et al. Nature Reviews Endocrinology
- ‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries
- (2008) Paul D. Dobson et al. DRUG DISCOVERY TODAY
- Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
- (2008) Paul D. Dobson et al. NATURE REVIEWS DRUG DISCOVERY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now