Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood
Authors
Keywords
-
Journal
XENOTRANSPLANTATION
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-09-28
DOI
10.1111/xen.12828
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pig endothelial protein C receptor is functionally compatible with the human protein C pathway
- (2019) Evelyn J. Salvaris et al. XENOTRANSPLANTATION
- Thromboxane and histamine mediate PVR elevation during xenogeneic pig lung perfusion with human blood
- (2018) Lars Burdorf et al. XENOTRANSPLANTATION
- Consistent success in life-supporting porcine cardiac xenotransplantation
- (2018) Matthias Längin et al. NATURE
- Cardiac xenografts show reduced survival in the absence of transgenic human thrombomodulin expression in donor pigs
- (2018) Avneesh K. Singh et al. XENOTRANSPLANTATION
- Platelet sequestration and activation during GalTKO.hCD46 pig lung perfusion by human blood is primarily mediated by GPIb, GPIIb/IIIa, and von Willebrand Factor
- (2016) Lars Burdorf et al. XENOTRANSPLANTATION
- Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft
- (2016) Muhammad M. Mohiuddin et al. Nature Communications
- Functional Difference Between Membrane-bound and Soluble Human Thrombomodulin
- (2015) Yuko Miwa et al. TRANSPLANTATION
- Human thrombomodulin regulates complement activation as well as the coagulation cascade in xeno-immune response
- (2015) Hwajung Kim et al. XENOTRANSPLANTATION
- Pig-to-baboon heterotopic heart transplantation - exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens
- (2015) Hayato Iwase et al. XENOTRANSPLANTATION
- Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein
- (2015) Agnes M. Azimzadeh et al. XENOTRANSPLANTATION
- Progress towards overcoming coagulopathy and hemostatic dysfunction associated with xenotransplantation
- (2015) Peter J. Cowan et al. International Journal of Surgery
- Four-Dimensional Characterization of Thrombosis in a Live-Cell, Shear-Flow Assay: Development and Application to Xenotransplantation
- (2015) Donald G. Harris et al. PLoS One
- Expression of Human CD46 Modulates Inflammation Associated With GalTKO Lung Xenograft Injury
- (2014) L. Burdorf et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade
- (2014) John C. LaMattina et al. XENOTRANSPLANTATION
- Development of a consensus protocol to quantify primate anti-non-Gal xenoreactive antibodies using pig aortic endothelial cells
- (2014) Agnes M. Azimzadeh et al. XENOTRANSPLANTATION
- Regulatory Sequences of the Porcine THBD Gene Facilitate Endothelial-Specific Expression of Bioactive Human Thrombomodulin in Single- and Multitransgenic Pigs
- (2013) Annegret Wuensch et al. TRANSPLANTATION
- Regulation of human platelet aggregation by genetically modified pig endothelial cells and thrombin inhibition
- (2013) Hayato Iwase et al. XENOTRANSPLANTATION
- Cardiac xenotransplantation
- (2012) Guerard W. Byrne et al. Current Opinion in Organ Transplantation
- Quantitative analysis of thrombomodulin-mediated conversion of protein C to APC: Translation from in vitro to in vivo
- (2012) Ronald Carnemolla et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Production of cloned pigs expressing human thrombomodulin in endothelial cells
- (2012) Satoko Yazaki et al. XENOTRANSPLANTATION
- B-Cell Depletion Extends the Survival of GTKO.hCD46Tg Pig Heart Xenografts in Baboons for up to 8 Months
- (2011) M. M. Mohiuddin et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection
- (2011) Bao-Ngoc H. Nguyen et al. XENOTRANSPLANTATION
- Molecular Intercommunication between the Complement and Coagulation Systems
- (2010) U. Amara et al. JOURNAL OF IMMUNOLOGY
- Potential value of human thrombomodulin and DAF expression for coagulation control in pig-to-human xenotransplantation
- (2010) Yuko Miwa et al. XENOTRANSPLANTATION
- Complement regulation in the GalT KO era
- (2010) Shuji Miyagawa et al. XENOTRANSPLANTATION
- Results of Gal-Knockout Porcine Thymokidney Xenografts
- (2009) A. D. Griesemer et al. AMERICAN JOURNAL OF TRANSPLANTATION
- The vascular and coagulation issues in xenotransplantation
- (2009) Peter J Cowan et al. Current Opinion in Organ Transplantation
- The discovery of the endothelial cell protein C receptor
- (2009) C. T. ESMON JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Pigs transgenic for human thrombomodulin have elevated production of activated protein C
- (2009) Björn Petersen et al. XENOTRANSPLANTATION
- Current status of xenotransplantation and prospects for clinical application
- (2009) Richard N. Pierson et al. XENOTRANSPLANTATION
- Pig Thrombomodulin Binds Human Thrombin but Is a Poor Cofactor for Activation of Human Protein C and TAFI
- (2008) J. C. Roussel et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Coagulation dysregulation as a barrier to xenotransplantation in the primate
- (2008) Chih Che Lin et al. TRANSPLANT IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started