Pig endothelial protein C receptor is functionally compatible with the human protein C pathway

Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates

(2018) Liaoran Wang et al.   TRANSPLANTATION

Consistent success in life-supporting porcine cardiac xenotransplantation

(2018) Matthias Längin et al.   NATURE

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

(2016) Muhammad M. Mohiuddin et al.   Nature Communications

Pig-to-baboon heterotopic heart transplantation - exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Regulatory Sequences of the Porcine THBD Gene Facilitate Endothelial-Specific Expression of Bioactive Human Thrombomodulin in Single- and Multitransgenic Pigs

(2013) Annegret Wuensch et al.   TRANSPLANTATION

Controlling coagulation dysregulation in xenotransplantation

(2011) Peter J Cowan et al.   Current Opinion in Organ Transplantation

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Antiinflammatory and Anticoagulant Effects of Transgenic Expression of Human Thrombomodulin in Mice

(2010) S. Crikis et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Identification of New Carbohydrate and Membrane Protein Antigens in Cardiac Xenotransplantation

(2010) Guerard W. Byrne et al.   TRANSPLANTATION

Pig Thrombomodulin Binds Human Thrombin but Is a Poor Cofactor for Activation of Human Protein C and TAFI

(2008) J. C. Roussel et al.   AMERICAN JOURNAL OF TRANSPLANTATION

New therapeutic applications for the anticoagulant, activated protein C

(2008) Chris Jackson et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells

(2008) J.-S. BAE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS