Article
Health Care Sciences & Services
Laney K. Jones, Marc S. Williams, Ilene G. Ladd, Dylan Cawley, Shuping Ge, Jing Hao, Dina Hassen, Yirui Hu, H. Lester Kirchner, Maria Kobylinski, Michael G. Lesko, Matthew C. Nelson, Alanna K. Rahm, David D. Rolston, Katrina M. Romagnoli, Tyler J. Schubert, Timothy C. Shuey, Amy C. Sturm, Samuel S. Gidding
Summary: The CARE-FH study aims to improve diagnostic evaluation rates for Familial Hypercholesterolemia (FH) through a collaborative approach. By using implementation science, the study transitions the initial evaluation for FH into primary care, in an attempt to identify individuals before the onset of atherosclerotic cardiovascular disease events.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Engineering, Environmental
Huie Chen, Xiang Gao, Qing Wang
Summary: With the expansion of engineering activities, frozen soil regions are experiencing a rise in major projects. However, due to the unique engineering properties of frozen soil, various engineering disasters have occurred or worsened due to global warming, posing a significant threat to project operation, environmental protection, and human development. This paper summarizes the formation conditions of frozen soil engineering disasters and provides prevention measures and research suggestions for a harmonious coexistence and sustainable development in frozen soil areas.
COLD REGIONS SCIENCE AND TECHNOLOGY
(2023)
Review
Gastroenterology & Hepatology
Zhongren Ma, Robert A. de Man, Nassim Kamar, Qiuwei Pan
Summary: The understanding and management of chronic hepatitis E have made some progress, but there are still many unanswered questions and challenges that require further advancement in research and patient care.
JOURNAL OF HEPATOLOGY
(2022)
Article
Orthopedics
Justin m. Losciale, Garrett s. Bullock, Gary s. Collins, Amelia j. h. Arundale, Tom Hughes, Nigel k. Arden, Jackie l. Whittaker
Summary: This article highlights the issue of premature and haphazard labeling of characteristics by researchers, resulting in confusion regarding clinical value and the distinction between risk factors/predictors. To address this problem, the article outlines the classification of different research goals and proposes a scientific process to follow before applying labels.
JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY
(2023)
Article
Social Issues
Paula Ferreira, Ana Rocha, Madalena Araujo, Joao L. Afonso, Carlos Henggeler Antunes, Marta A. R. Lopes, Gerardo J. Osorio, Joao P. S. Catalao, Joao Pecas Lopes
Summary: This paper analyzes the potential societal impacts of research projects with low technology readiness level, using the case of the ESGRIDS project as an example. The study highlights the influence of individual perceptions and organizational contexts on future developments. The analysis is translated into a technology roadmap, which outlines the time dimension for technology maturity evolution and implementation impacts.
TECHNOLOGY IN SOCIETY
(2023)
Article
Cardiac & Cardiovascular Systems
Gary Schwartz, Eleanor A. Huff, Johanna S. van Zyl, Briget da Graca, Gonzalo Gonzalez-Stawinski, Jorge Velazco, Timothy George, Michael J. Mack, Dan M. Meyer
Summary: This study evaluated the impact of coordinating and standardizing ECMO programs within a healthcare system. The results showed that the implementation of the ECMO collaborative project significantly improved patient survival rates, successful weaning from ECMO, and reduced complication rates.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Public, Environmental & Occupational Health
Eric Nguemeleu Tchouaket, Drissa Sia, Sylvain Brousseau, Kelley Kilpatrick, Sandra Boivin, Bruno Dubreuil, Catherine Larouche, Natasha Parisien, Carl-Ardy Dubois, Astrid Brousselle, Roxane Borges Da Silva
Summary: This project aims to evaluate the efficiency of hospital infection control measures in Quebec, Canada through four components of research including cost assessment of CBPs, economic burden evaluation of nosocomial infections, and cost-effectiveness analysis of NIPC.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Oncology
Faiza Gaba, Karen Ash, Oleg Blyuss, Nicolo Bizzarri, Paul Kamfwa, Pedro T. Ramirez, Ioannis C. Kotsopoulos, Dhivya Chandrasekaran, Nana Gomes, John Butler, Marielle Nobbenhuis, Thomas Ind, Owen Heath, Desmond Barton, Arjun Jeyarajah, Elly Brockbank, Alexandra Lawrence, James Dilley, Ranjit Manchanda, Saurabh Phadnis, G. O. Soar
Summary: The Global Gynecological Oncology Surgical Outcomes Collaborative (GO SOAR) has developed a network of professionals to collaborate on outcome studies. This article presents the protocol for the GO SOAR2 study, which aims to compare survival following different surgical treatments for ovarian cancer and assess international variations in access to cytoreductive surgery.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Oncology
Scott S. Short, Zachary J. Kastenberg, Guo Wei, Alex Bondoc, Roshni Dasgupta, Greg M. Tiao, Erin Watters, Todd E. Heaton, Dimitra Lotakis, Michael P. La Quaglia, Andrew J. Murphy, Andrew M. Davidoff, Sara A. Mansfield, Max R. Langham, Timothy B. Lautz, Riccardo A. Superina, Katherine C. Ott, Marcus M. Malek, Katrina M. Morgan, Eugene S. Kim, Abigail Zamora, Danny Lascano, Jonathan Roach, Joseph T. Murphy, David H. Rothstein, Sanjeev A. Vasudevan, Richard Whitlock, Dave R. Lal, Brian Hallis, Andreana Butter, Reto M. Baertschiger, Eveline Lapidus-Krol, Juan Putra, Elisabeth R. Tracy, Jennifer H. Aldrink, Jordan Apfeld, Hau D. Le, Keon Y. Park, Barrie S. Rich, Richard D. Glick, Elizabeth A. Fialkowski, Alan F. Utria, Rebecka L. Meyers, Kimberly J. Riehle
Summary: This study provides the largest detailed dataset on children with hepatocellular carcinoma. It identifies key differences between subtypes of hepatocellular carcinoma, which is crucial for improving understanding and clinical management of these rare cancers.
Article
Obstetrics & Gynecology
Jennifer F. Kawwass, Sara Crawford, Heather S. Hipp
Summary: This study aimed to characterize national outcomes of oocyte thaw cycles in the United States and found that pregnancy and live birth rates decreased with increasing age at oocyte cryopreservation, as did the number of oocytes needed to achieve one live birth.
FERTILITY AND STERILITY
(2021)
Article
Food Science & Technology
Elisabeth M. Weir, Danielle R. Reed, M. Yanina Pepino, Maria G. Veldhuizen, John E. Hayes
Summary: This article describes the establishment of the Global Consortium of Chemosensory Research (GCCR), the tools and approaches used, and the findings to date. The study provides insights into chemosensation and COVID-19, including potential mechanisms of loss. Additionally, it discusses in detail the current Open Science approaches and practices used by the GCCR to enhance transparency, rigor, and reproducibility.
FOOD QUALITY AND PREFERENCE
(2022)
Review
Medicine, General & Internal
Joanna Yang, Tori Barabash, Luckshi Rajendran, Alyson L. Mahar, Amy T. Hsu, Paul D. James, Lesley Gotlib Conn, Frances C. Wright, Claire Ludwig, Ekaterina Kosyachkova, Julie Deleemans, Natalie G. Coburn, Julie Hallet
Summary: This article aims to summarize the existing literature on patient-centred outcomes (PCOs) in gastrointestinal cancer care and analyze the tools used to assess these outcomes. By screening relevant studies and extracting data, a comprehensive list of PCOs will be generated for future development of a core outcome set. This is crucial for aiding patients in making informed and meaningful care decisions.
Article
Critical Care Medicine
Kerri Aronson, Sonye K. Danoff, Anne-Marie Russell, Christopher J. Ryerson, Atsushi Suzuki, Marlies S. Wijsenbeek, Sabrina Bajwah, Pauline Bianchi, Tamera J. Corte, Joyce S. Lee, Kathleen O. Lindell, Toby Maher, Fernando J. Martinez, Paula M. Meek, Ganesh Raghu, Glenda Rouland, Rick Rudell, Monika M. Safford, Jamie S. Sheth, Jeffrey J. Swigris
Summary: This study highlights the importance of patient-centered outcomes in ILD research and the need for more dedicated work in this area. The interdisciplinary group of experts identified key patient-centered outcomes and developed research recommendations to further advance this field. Despite progress made in understanding and treating ILD, there are still unanswered questions related to patient outcomes and therapies.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Oncology
Dide den Hollander, Marco Fiore, Javier Martin-Broto, Bernd Kasper, Antonio Casado Herraez, Dagmara Kulis, Ioanna Nixon, Samantha C. Sodergren, Martin Eichler, Winan J. van Houdt, Ingrid M. E. Desar, Isabelle Ray-Coquard, Claire Piccinin, Hanna Kosela-Paterczyk, Aisha Miah, Leopold Hentschel, Susanne Singer, Roger Wilson, Winette T. A. van der Graaf, Olga Husson
Summary: Sarcomas are a rare and heterogeneous group of tumors, making it challenging to develop a specific HRQoL measurement instrument. This study aims to create a list of HRQoL issues relevant to sarcoma patients and determine a strategy for HRQoL assessment through an international, multicenter approach. By involving sarcoma patients and healthcare professionals in rating and prioritizing these issues, a tailored framework for HRQoL measurement in sarcoma patients will be established.
Article
Medicine, General & Internal
David M. Nathan, GRADE Study Res Grp, John M. Lachin, Ashok Balsubramanyam, Henry B. Burch, John B. Buse, Nicole M. Butera, Robert M. Cohen, Jill P. Crandall, Steven E. Kahn, Heidi Krause-Steinrauf, Mary E. Larkin, Neda Rasouli, Margaret Tiktin, Deborah J. Wexler, Naji Younes
Summary: In this trial, all four glucose-lowering medications added to metformin were effective in reducing glycated hemoglobin levels. Glargine and liraglutide showed modestly superior efficacy in achieving and maintaining target glycated hemoglobin levels.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Matthew Aitken, Malcolm Davidson, Michael Chan, Camila Urzua Fresno, Leon I. Vasquez, Ya R. Huo, Brylie J. McAllister, Jordi Broncano, Paaladinesh Thavendiranathan, Matthew D. F. McInnes, Mark R. Iwanochko, Meyer Balter, Yasbanoo Moayedi, Ashley Farrell, Kate Hanneman
Summary: There is no consensus on the prognostic value of cardiac MRI and FDG PET in cardiac sarcoidosis. A systematic review and meta-analysis found that left and right ventricular late gadolinium enhancement at cardiac MRI and fluorodeoxyglucose uptake at PET were predictive of major adverse cardiac events in cardiac sarcoidosis.