Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma

BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti‐PD‐1/PD‐L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity

(2023) Zhiyong Cai et al.   Advanced Science

S100A5 Attenuates Efficiency of Anti‐PD‐L1/PD‐1 Immunotherapy by Inhibiting CD8+ T Cell‐Mediated Anti‐Cancer Immunity in Bladder Carcinoma

(2023) Huihuang Li et al.   Advanced Science

Identification of Germline Mutations in Upper Tract Urothelial Carcinoma With Suspected Lynch Syndrome

(2022) Bao Guan et al.   Frontiers in Oncology

Lynch Syndrome: From Carcinogenesis to Prevention Interventions

(2022) Donatella Gambini et al.   Cancers

5mC regulator-mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer

(2021) Jiao Hu et al.   BMC Medicine

Universal Point of Care Testing for Lynch Syndrome in Patients with Upper Tract Urothelial Carcinoma

(2018) Michael J. Metcalfe et al.   JOURNAL OF UROLOGY

Two-stain immunohistochemical screening for Lynch syndrome in colorectal cancer may fail to detect mismatch repair deficiency

(2018) Rachel Pearlman et al.   MODERN PATHOLOGY

A Whole-genome CRISPR Screen Identifies a Role of MSH2 in Cisplatin-mediated Cell Death in Muscle-invasive Bladder Cancer

(2018) Andrew Goodspeed et al.   EUROPEAN UROLOGY

Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma

(2016) D. J. Kwiatkowski et al.   CLINICAL CANCER RESEARCH

Mismatch repair defects and Lynch syndrome: The role of the basic scientist in the battle against cancer

(2016) Christopher D. Heinen   DNA REPAIR

Importance of universal mismatch repair protein immunohistochemistry in patients with sebaceous neoplasia as an initial screening tool for Muir-Torre syndrome

(2016) Chad J. Jessup et al.   HUMAN PATHOLOGY

ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes

(2015) Sapna Syngal et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Defective DNA mismatch repair activity is common in sebaceous neoplasms, and may be an ineffective approach to screen for Lynch syndrome

(2015) Anu R. Lamba et al.   Familial Cancer

Urinary Tract Cancer in Lynch Syndrome; Increased Risk in Carriers of MSH2 Mutations

(2015) Patrick Joost et al.   UROLOGY

Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

(2014) Francis M. Giardiello et al.   GASTROENTEROLOGY

Screening for Germline Mismatch Repair Mutations Following Diagnosis of Sebaceous Neoplasm

(2014) Jessica N. Everett et al.   JAMA Dermatology

A proportion of hereditary upper urinary tract urothelial carcinomas are misclassified as sporadic according to a multi-institutional database analysis: proposal of patient-specific risk identification tool

(2012) François Audenet et al.   BJU INTERNATIONAL

Accurate classification ofMLH1/MSH2missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR)

(2008) Elizabeth C. Chao et al.   HUMAN MUTATION