Combination of hydrophobicity and codon usage bias determines sorting of model K+ channel protein to either mitochondria or endoplasmic reticulum

Codon Bias Can Determine Sorting of a Potassium Channel Protein

(2021) Anja J. Engel et al.   Cells

ER-SURF: Riding the Endoplasmic Reticulum Surface to Mitochondria

(2021) Christian Koch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Capture and delivery of tail-anchored proteins to the endoplasmic reticulum

(2021) Ákos Farkas et al.   JOURNAL OF CELL BIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

Array programming with NumPy

(2020) Charles R. Harris et al.   NATURE

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Light-Regulated Transcription of a Mitochondrial-Targeted K+ Channel

(2020) Anja J. Engel et al.   Cells

The impact of ribosomal interference, codon usage, and exit tunnel interactions on translation elongation rate variation

(2018) Khanh Dao Duc et al.   PLoS Genetics

A structural perspective on tail-anchored protein biogenesis by the GET pathway

(2018) Agnieszka Mateja et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The stop and go traffic regulating protein biogenesis: how translation kinetics control proteostasis

(2018) Kevin C. Stein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Codon optimality, bias and usage in translation and mRNA decay

(2017) Gavin Hanson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physical Origins of Codon Positions That Strongly Influence Cotranslational Folding: A Framework for Controlling Nascent-Protein Folding

(2016) Ajeet K. Sharma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cotranslational Intersection between the SRP and GET Targeting Pathways to the Endoplasmic Reticulum of Saccharomyces cerevisiae

(2016) Ying Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Synonymous Codons Direct Cotranslational Folding toward Different Protein Conformations

(2016) Florian Buhr et al.   MOLECULAR CELL

The SND proteins constitute an alternative targeting route to the endoplasmic reticulum

(2016) Naama Aviram et al.   NATURE

Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding

(2015) Chien-Hung Yu et al.   MOLECULAR CELL

The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum

(2015) M. Gamerdinger et al.   SCIENCE

Computational evidence that fast translation speed can increase the probability of cotranslational protein folding

(2015) Ercheng Wang et al.   Scientific Reports

Local slowdown of translation by nonoptimal codons promotes nascent-chain recognition by SRP in vivo

(2014) Sebastian Pechmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A critical analysis of codon optimization in human therapeutics

(2014) Vincent P. Mauro et al.   TRENDS IN MOLECULAR MEDICINE

Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex

(2013) Helen R. Watson et al.   BIOCHEMICAL JOURNAL

Non-optimal codon usage affects expression, structure and function of clock protein FRQ

(2013) Mian Zhou et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mechanisms of Protein Sorting in Mitochondria

(2012) D. Stojanovski et al.   Cold Spring Harbor Perspectives in Biology

A third of the yeast mitochondrial proteome is dual localized: A question of evolution

(2011) Reut Ben-Menachem et al.   PROTEOMICS

Minimal art: Or why small viral K+ channels are good tools for understanding basic structure and function relations

(2010) Gerhard Thiel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Targeting pathways of C-tail-anchored proteins

(2010) Nica Borgese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Protein targeting by the signal recognition particle

(2009) Przemyslaw Grudnik et al.   BIOLOGICAL CHEMISTRY

The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane

(2008) Maya Schuldiner et al.   CELL

Transmembrane domain length of viral K+ channels is a signal for mitochondria targeting

(2008) J. Balss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA