Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells

Asthma

(2023) Celeste Porsbjerg et al.   LANCET

Berberine-loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

(2022) Keshav R. Paudel et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases

(2022) Daljeet Singh Dhanjal et al.   Future Medicinal Chemistry

Advancements in nanotherapeutics targeting senescence in chronic obstructive pulmonary disease

(2022) Keshav Raj Paudel et al.   Nanomedicine

Unravelling the molecular mechanisms underlying chronic respiratory diseases for the development of novel therapeutics via in vitro experimental models

(2022) Ching Leng Tan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expanding the arsenal against pulmonary diseases using surface-functionalized polymeric micelles: breakthroughs and bottlenecks

(2022) Rubiya Khursheed et al.   Nanomedicine

Evaluation of the Cytotoxic Activity and Anti-Migratory Effect of Berberine–Phytantriol Liquid Crystalline Nanoparticle Formulation on Non-Small-Cell Lung Cancer In Vitro

(2022) Abdullah M. Alnuqaydan et al.   Pharmaceutics

Role of oxidative stress in the pathogenesis of COPD

(2022) Francesco NUCERA et al.   MINERVA MEDICA

Berberine inhibits glioma cell migration and invasion by suppressing TGF-β1/COL11A1 pathway

(2022) Yuxue Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting mucus barrier in respiratory diseases by chemically modified advanced delivery systems

(2022) Parteek Prasher et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Unravelling the Therapeutic Potential of Nano-Delivered Functional Foods in Chronic Respiratory Diseases

(2022) Dvya Delilaa Clarence et al.   Nutrients

An open microfluidic coculture model of fibroblasts and eosinophils to investigate mechanisms of airway inflammation

(2022) Yuting Zeng et al.   Frontiers in Bioengineering and Biotechnology

Phytantriol-Based Berberine-Loaded Liquid Crystalline Nanoparticles Attenuate Inflammation and Oxidative Stress in Lipopolysaccharide-Induced RAW264.7 Macrophages

(2022) Abdullah M. Alnuqaydan et al.   Nanomaterials

Research Progress on Therapeutic Targeting of Cancer-Associated Fibroblasts to Tackle Treatment-Resistant NSCLC

(2022) Chenxin Li et al.   Pharmaceuticals

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease

(2021) Sebastian T Lugg et al.   THORAX

Advanced drug delivery approaches in managing TGF-β-mediated remodeling in lung diseases

(2021) Gaurav Gupta et al.   Nanomedicine

Versatility of liquid crystalline nanoparticles in inflammatory lung diseases

(2021) Yinghan Chan et al.   Nanomedicine

Therapeutic targets in lung tissue remodelling and fibrosis

(2021) Gang Liu et al.   PHARMACOLOGY & THERAPEUTICS

Airway-On-A-Chip: Designs and Applications for Lung Repair and Disease

(2021) Tanya J. Bennet et al.   Cells

Inhalation delivery of repurposed drugs for lung cancer: Approaches, benefits and challenges

(2021) Popat Kumbhar et al.   JOURNAL OF CONTROLLED RELEASE

Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro

(2021) Meenu Mehta et al.   JOURNAL OF FOOD BIOCHEMISTRY

Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGFβR Regulating TGF-β/Smad Pathway

(2021) Haiyan Du et al.   Oxidative Medicine and Cellular Longevity

Incipient need of targeting airway remodeling using advanced drug delivery in chronic respiratory diseases

(2020) Meenu Mehta et al.   Future Medicinal Chemistry

Global Burden of Chronic Respiratory Diseases

(2020) Giovanni Viegi et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Chronic respiratory diseases: a global view

(2020) Wassim W Labaki et al.   Lancet Respiratory Medicine

What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma?

(2020) Emmanuel Twumasi Osei et al.   Cells

Rutin loaded liquid crystalline nanoparticles inhibit lipopolysaccharide induced oxidative stress and apoptosis in bronchial epithelial cells in vitro

(2020) Keshav Raj Paudel et al.   TOXICOLOGY IN VITRO

Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease

(2019) Craig M. Riley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Berberine inhibits epithelial-mesenchymal transition and promotes apoptosis of tumour-associated fibroblast-induced colonic epithelial cells through regulation of TGF-β signalling

(2019) Chao Huang et al.   Journal of Cell Communication and Signaling

Non-small Cell Lung Cancer as a Chronic Disease – A Prospective Study from the Czech TULUNG Registry

(2019) MONIKA BRATOVA et al.   IN VIVO

Berberine Suppresses Cell Motility Through Downregulation of TGF-β1 in Triple Negative Breast Cancer Cells

(2018) Sangmin Kim et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TGF-β Signaling in Lung Health and Disease

(2018) Akira Saito et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of inflammatory cells in airway remodeling in COPD

(2018) Yujie Wang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems

(2018) Kamal Dua et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Berberine alleviates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress

(2017) Li-Chao Zhang et al.   Experimental and Therapeutic Medicine

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis

(2017) Kelly L. Walton et al.   Frontiers in Pharmacology

Idiopathic pulmonary fibrosis

(2017) Fernando J. Martinez et al.   Nature Reviews Disease Primers

Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease

(2016) Yael Aschner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Naringenin inhibits migration of lung cancer cells via the inhibition of matrix metalloproteinases-2 and −9

(2016) Huai-Lu Chang et al.   Experimental and Therapeutic Medicine

Airway Remodeling in Chronic Obstructive Pulmonary Disease and Asthma: the Role of Matrix Metalloproteinase-9

(2015) Katarzyna Grzela et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Biological Activity Differences between TGF-β1 and TGF-β3 Correlate with Differences in the Rigidity and Arrangement of Their Component Monomers

(2014) Tao Huang et al.   BIOCHEMISTRY

Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis

(2014) Hui-wei Qi et al.   Journal of Translational Medicine

Preclinical Efficacy of Cystatin C to Target the Oncogenic Activity of Transforming Growth Factor β in Breast Cancer

(2014) Maozhen Tian et al.   Translational Oncology

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2013) Jörg D. Leuppi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study

(2013) Palanivel Chitra et al.   TOXICOLOGY LETTERS

Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

(2012) Mariya T. Sweetwyne et al.   MATRIX BIOLOGY

Role of Transforming Growth Factor–β in Airway Remodeling in Asthma

(2010) Rabih Halwani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Allergen-Induced Coexpression of bFGF and TGF-β1 by Macrophages in a Mouse Model of Airway Remodeling: bFGF Induces Macrophage TGF-β1 Expression in vitro

(2010) Hye Young Yum et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Berberine inhibits angiogenic potential of Hep G2 cell line through VEGF down-regulation in vitro

(2010) Shenghua Jie et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin

(2009) Chunmei Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TGF-β effects on airway smooth muscle cell proliferation, VEGF release and signal transduction pathways

(2009) Joo Hwa SHIN et al.   RESPIROLOGY

Effect of Pharmacotherapy on Rate of Decline of Lung Function in Chronic Obstructive Pulmonary Disease

(2008) Bartolomé R. Celli et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TGFβ in Cancer

(2008) Joan Massagué   CELL

Efficacy of berberine in patients with type 2 diabetes mellitus

(2008) Jun Yin et al.   METABOLISM-CLINICAL AND EXPERIMENTAL