Recombinant Klotho alleviates vancomycin-induced acute kidney injury by upregulating anti-oxidative capacity via JAK2/STAT3/GPx3 axis

Vitamin D–vitamin D receptor alleviates oxidative stress in ischemic acute kidney injury via upregulating glutathione peroxidase 3

(2022) Xueqin Wu et al.   FASEB JOURNAL

In vivo and in vitro studies on inactivation of selenium containing protein- glutathione peroxidase 3 in mice nephrocytes caused by lead

(2020) Hao Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The efficiency of pomegranate (Punica granatum) peel ethanolic extract in attenuating the vancomycin-triggered liver and kidney tissues injury in rats

(2020) Khlood M. El Bohi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Sinomenine improve diabetic nephropathy by inhibiting fibrosis and regulating the JAK2/STAT3/SOCS1 pathway in streptozotocin-induced diabetic rats

(2020) Maolin Zhu et al.   LIFE SCIENCES

Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution

(2019) Renuga Devi Rajaram et al.   Redox Biology

Systematic Review and Meta-analysis of the Association of Acute Kidney Injury with the Concomitant Use of Vancomycin and Piperacillin-Tazobactam in Children

(2019) Markos Kalligeros et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease

(2018) Kranti A. Mapuskar et al.   Redox Biology

The role of klotho in chronic kidney disease

(2018) Di Zou et al.   BMC Nephrology

Association between Soluble Klotho and Change in Kidney Function: The Health Aging and Body Composition Study

(2017) David A. Drew et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Vancomycin-Associated Cast Nephropathy

(2017) Yosu Luque et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cilastatin attenuates vancomycin-induced nephrotoxicity via P-glycoprotein

(2017) Dai sig Im et al.   TOXICOLOGY LETTERS

Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress

(2017) Sun Woo Lim et al.   Cell Death & Disease

Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway

(2016) Jian Jin et al.   AMERICAN JOURNAL OF NEPHROLOGY

Oxidant Mechanisms in Renal Injury and Disease

(2016) Brian B. Ratliff et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular Basis of Klotho: From Gene to Function in Aging

(2015) Yuechi Xu et al.   ENDOCRINE REVIEWS

 Klotho Mitigates Progression of AKI to CKD through Activation of Autophagy

(2015) M. Shi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH Oxidases, Reactive Oxygen Species, and the Kidney: Friend and Foe

(2013) M. Sedeek et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New Role of JAK2/STAT3 Signaling in Endothelial Cell Oxidative Stress Injury and Protective Effect of Melatonin

(2013) Weixun Duan et al.   PLoS One

Klotho gene delivery suppresses Nox2 expression and attenuates oxidative stress in rat aortic smooth muscle cells via the cAMP-PKA pathway

(2012) Yuhong Wang et al.   AGING CELL

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial superoxide production contributes to vancomycin-induced renal tubular cell apoptosis

(2012) Yohei Arimura et al.   FREE RADICAL BIOLOGY AND MEDICINE

p53-induced Gene 3 Mediates Cell Death Induced by Glutathione Peroxidase 3

(2012) Hui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for GPx3 in activity of normal and leukemia stem cells

(2012) Olivier Herault et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response

(2011) Baishen Chen et al.   CANCER LETTERS

The Inflammatory Cytokines TWEAK and TNF  Reduce Renal Klotho Expression through NF B

(2011) J. A. Moreno et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective

(2010) Ming-Chang Hu et al.   KIDNEY INTERNATIONAL

Klotho reduces apoptosis in experimental ischaemic acute kidney injury via HSP-70

(2009) H. Sugiura et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION