Clustering minimal inhibitory concentration data through Bayesian mixture models: An application to detect Mycobacteriumtuberculosis resistance mutations

Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan

(2022) Gary Napier et al.   Scientific Reports

Whole Genome Sequencing Identifies Novel Mutations Associated With Bedaquiline Resistance in Mycobacterium tuberculosis

(2022) Qinglong Guo et al.   Frontiers in Cellular and Infection Microbiology

Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages

(2021) Delphine Payros et al.   PLoS Pathogens

Bedaquiline-resistant Tuberculosis: Dark Clouds on the Horizon

(2020) Sönke Andres et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic

(2020) Marisa Klopper et al.   BMC Medicine

Protein–protein interaction of Rv0148 with Htdy and its predicted role towards drug resistance in Mycobacterium tuberculosis

(2020) Gunapati Bhargavi et al.   BMC MICROBIOLOGY

Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs

(2020) Agathe Jouet et al.   EUROPEAN RESPIRATORY JOURNAL

Clofazimine exposure in vitro selects efflux pump mutants and bedaquiline resistance

(2019) Nabila Ismail et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rifampicin and rifabutin resistance in 1003 Mycobacterium tuberculosis clinical isolates

(2019) Maha R Farhat et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of Whole-Genome Sequence Method to Diagnose Resistance of 13 Anti-tuberculosis Drugs and Characterize Resistance Genes in Clinical Multi-Drug Resistance Mycobacterium tuberculosis Isolates From China

(2019) Xinchang Chen et al.   Frontiers in Microbiology

Phenotypic and genotypic characterization of levofloxacin- and moxifloxacin-resistant Mycobacterium tuberculosis clinical isolates in southern China

(2019) H. M. Adnan Hameed et al.   Journal of Thoracic Disease

On a loss-based prior for the number of components in mixture models

(2019) Clara Grazian et al.   STATISTICS & PROBABILITY LETTERS

Validating a 14-drug microtitre plate containing bedaquiline and delamanid for large-scale research susceptibility testing of Mycobacterium tuberculosis

(2018) Paola M. V. Rancoita et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Jeffreys priors for mixture estimation: Properties and alternatives

(2018) Clara Grazian et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS

A tutorial on conducting genome-wide association studies: Quality control and statistical analysis

(2018) Andries T. Marees et al.   INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH

Molecular Mechanisms of Drug Tolerance in Mycobacterium tuberculosis

(2018) A. V. Antonova et al.   MOLECULAR BIOLOGY

Defining Bedaquiline Susceptibility, Resistance, Cross-Resistance and Associated Genetic Determinants: A Retrospective Cohort Study

(2018) Nazir A. Ismail et al.   EBioMedicine

Signatures of Selection at Drug Resistance Loci in Mycobacterium tuberculosis

(2018) Tatum D. Mortimer et al.   mSystems

Bayesian Nonparametric Modeling for Multivariate Ordinal Regression

(2017) Maria DeYoreo et al.   JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS

Mixture Models With a Prior on the Number of Components

(2017) Jeffrey W. Miller et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

(2017) Keertan Dheda et al.   Lancet Respiratory Medicine

A Bayesian approach to the semiparametric estimation of a minimum inhibitory concentration distribution

(2016) Stijn Jaspers et al.   Annals of Applied Statistics

Mutations inpepQConfer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis

(2016) Deepak Almeida et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identifying lineage effects when controlling for population structure improves power in bacterial association studies

(2016) Sarah G. Earle et al.   Nature Microbiology

Identification of novel mutations associated with clofazimine resistance inMycobacterium tuberculosis: Table 1.

(2015) Shuo Zhang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study

(2015) Timothy M Walker et al.   LANCET INFECTIOUS DISEASES

Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315

(2015) Rose E. Jeeves et al.   PLoS One

Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis

(2014) R. C. Hartkoorn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multidrug-resistant tuberculosis around the world: what progress has been made?

(2014) D. Falzon et al.   EUROPEAN RESPIRATORY JOURNAL

A new semi-parametric mixture model for interval censored data, with applications in the field of antimicrobial resistance

(2013) Stijn Jaspers et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS

High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations

(2013) Diana Machado et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Estimation of the wild-type minimum inhibitory concentration value distribution

(2013) Stijn Jaspers et al.   STATISTICS IN MEDICINE

Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

(2012) Magnus Unemo et al.   Future Microbiology

Linezolid for Treatment of Chronic Extensively Drug-Resistant Tuberculosis

(2012) Myungsun Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive Multicenter Evaluation of a New Line Probe Assay Kit for Identification of Mycobacterium Species and Detection of Drug-Resistant Mycobacterium tuberculosis

(2011) S. Mitarai et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Asymptotic behaviour of the posterior distribution in overfitted mixture models

(2011) Judith Rousseau et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Molecular Investigation of Resistance to the Antituberculous Drug Ethionamide in Multidrug-Resistant Clinical Isolates ofMycobacterium tuberculosis

(2010) F. Brossier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutations in Extensively Drug‐ResistantMycobacterium tuberculosisThat Do Not Code for Known Drug‐Resistance Mechanisms

(2010) Alifiya S. Motiwala et al.   JOURNAL OF INFECTIOUS DISEASES

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo

(2010) Nicole A. Kruh et al.   PLoS One

Genomic Diversity among Drug Sensitive and Multidrug Resistant Isolates of Mycobacterium tuberculosis with Identical DNA Fingerprints

(2009) Stefan Niemann et al.   PLoS One

Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models

(2009) M. Sperrin et al.   STATISTICS AND COMPUTING

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols