Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice

Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond

(2023) Christian Weber et al.   EUROPEAN HEART JOURNAL

High immunoglobulin-M levels to oxidation-specific epitopes are associated with lower risk of acute myocardial infarction

(2023) Adam Taleb et al.   JOURNAL OF LIPID RESEARCH

Endothelial Retargeting of AAV9 In Vivo

(2022) Tarik Bozoglu et al.   Advanced Science

Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease

(2022) Donato Santovito et al.   Nature Reviews Cardiology

Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm

(2022) Raquel Roldán-Montero et al.   Science Advances

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

(2022) Krishna G. Aragam et al.   NATURE GENETICS

Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation

(2021) Jiro Ikeda et al.   CIRCULATION RESEARCH

Chemokine Receptor-6 Promotes B-1 Cell Trafficking to Perivascular Adipose Tissue, Local IgM Production and Atheroprotection

(2021) Prasad Srikakulapu et al.   Frontiers in Immunology

Profiling of Primary and Mature miRNA Expression in Atherosclerosis Associated Cell Types

(2021) Pierre R. Moreau et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions

(2021) Hsi-Yuan Huang et al.   NUCLEIC ACIDS RESEARCH

B-Cell Specific CXCR4 Protects Against Atherosclerosis Development and Increases Plasma IgM Levels

(2020) Yvonne Döring et al.   CIRCULATION RESEARCH

Engineering adeno-associated virus vectors for gene therapy

(2020) Chengwen Li et al.   NATURE REVIEWS GENETICS

Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol

(2020) Kausik K. Ray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Position-specific oxidation of miR-1 encodes cardiac hypertrophy

(2020) Heeyoung Seok et al.   NATURE

Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis

(2020) Donato Santovito et al.   Science Translational Medicine

Small Things Matter: Relevance of MicroRNAs in Cardiovascular Disease

(2020) Linsey J. F. Peters et al.   Frontiers in Physiology

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

(2020) Theo Vos et al.   LANCET

Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

(2020) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

(2020) Lindsey R. Baden et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease

(2019) Yvonne Döring et al.   CIRCULATION

Immunotherapy for cardiovascular disease

(2019) Esther Lutgens et al.   EUROPEAN HEART JOURNAL

Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked To Human Coronary Atherosclerosis

(2019) Aditi Upadhye et al.   CIRCULATION RESEARCH

MirGeneDB 2.0: the metazoan microRNA complement

(2019) Bastian Fromm et al.   NUCLEIC ACIDS RESEARCH

Double bond configuration of palmitoleate is critical for atheroprotection

(2019) Ismail Cimen et al.   Molecular Metabolism

Anti-Oxidized LDL Antibodies and Coronary Artery Disease: A Systematic Review

(2019) Victor J. van den Berg et al.   Antioxidants

The biochemical basis of microRNA targeting efficacy

(2019) Sean E. McGeary et al.   SCIENCE

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis

(2018) Carla Winter et al.   Cell Metabolism

Dicer in Macrophages Prevents Atherosclerosis by Promoting Mitochondrial Oxidative Metabolism

(2018) Yuanyuan Wei et al.   CIRCULATION

UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease

(2018) Leonardo Elia et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

miR-103 promotes endothelial maladaptation by targeting lncWDR59

(2018) Lucia Natarelli et al.   Nature Communications

zUMIs - A fast and flexible pipeline to process RNA sequencing data with UMIs

(2018) Swati Parekh et al.   GigaScience

Toward the human cellular microRNAome

(2017) Matthew N. McCall et al.   GENOME RESEARCH

An integrated expression atlas of miRNAs and their promoters in human and mouse

(2017) Derek de Rie et al.   NATURE BIOTECHNOLOGY

Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair

(2016) Farima Zahedi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation

(2016) Ismail Çimen et al.   Science Translational Medicine

MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation

(2016) Irinna Papangeli et al.   Nature Communications

Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4

(2016) Petra Hartmann et al.   Nature Communications

A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome

(2015) Bastian Fromm et al.   Annual Review of Genetics

The selection and function of cell type-specific enhancers

(2015) Sven Heinz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

(2014) Andreas Schober et al.   NATURE MEDICINE

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

(2014) B-H Li et al.   Cell Death & Disease

Update on acute coronary syndromes: the pathologists' view

(2012) Erling Falk et al.   EUROPEAN HEART JOURNAL

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

A Tale of Coronary Artery Disease and Myocardial Infarction

(2012) Elizabeth G. Nabel et al.   NEW ENGLAND JOURNAL OF MEDICINE

MAGIA2: from miRNA and genes expression data integrative analysis to microRNA-transcription factor mixed regulatory circuits (2012 update)

(2012) A. Bisognin et al.   NUCLEIC ACIDS RESEARCH

Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach

(2012) X. A. Cambronne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

(2009) M. J. Christopher et al.   BLOOD

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

(2009) L Elia et al.   CELL DEATH AND DIFFERENTIATION

Reciprocal Regulation of MicroRNA-1 and Insulin-Like Growth Factor-1 Signal Transduction Cascade in Cardiac and Skeletal Muscle in Physiological and Pathological Conditions

(2009) Leonardo Elia et al.   CIRCULATION

GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions

(2009) Su-Ning Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

(2009) Kimberly R. Cordes et al.   NATURE

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

(2008) Catherine Labbaye et al.   NATURE CELL BIOLOGY

Protective Role of CXC Receptor 4/CXC Ligand 12 Unveils the Importance of Neutrophils in Atherosclerosis

(2007) Alma Zernecke et al.   CIRCULATION RESEARCH