Uterine Collagen Cross-Linking: Biology, Role in Disorders, and Therapeutic Implications

Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy

(2022) Nicole Lee et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

AP-1 Subunit JUNB Promotes Invasive Phenotypes in Endometriosis

(2022) Mike R. Wilson et al.   Reproductive Sciences

Three-dimensional anisotropic hyperelastic constitutive model describing the mechanical response of human and mouse cervix

(2022) Lei Shi et al.   Acta Biomaterialia

Endometriosis: Cellular and Molecular Mechanisms Leading to Fibrosis

(2022) Jose Manuel Garcia Garcia et al.   Reproductive Sciences

Pathophysiology, diagnosis, and management of endometriosis

(2022) Andrew W Horne et al.   BMJ-British Medical Journal

Transcriptome and proteome dynamics of cervical remodeling in the mouse during pregnancy

(2021) Shanmugasundaram Nallasamy et al.   BIOLOGY OF REPRODUCTION

Establishment of a Novel In Vitro Model of Endometriosis with Oncogenic KRAS and PIK3CA Mutations for Understanding the Underlying Biology and Molecular Pathogenesis

(2021) Mohammad Mahmud Hossain et al.   Cancers

Collagen crosslinking: effect on structure, mechanics and fibrosis progression

(2021) Wenyu Kong et al.   Biomedical Materials

Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy

(2021) Mariano Colon-Caraballo et al.   MATRIX BIOLOGY

Preimplantation embryo development and function is compromised by concentrations of Advanced Glycation End Products present within the obese uterine environment

(2020) J Hutchison et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Extracellular Matrix Rigidity Modulates Human Cervical Smooth Muscle Contractility—New Insights into Premature Cervical Failure and Spontaneous Preterm Birth

(2020) Joy Vink et al.   Reproductive Sciences

TGF-β1 Neutralization Improves Pregnancy Outcomes by Restoring Endometrial Receptivity in Mice with Adenomyosis

(2020) Nari Kay et al.   Reproductive Sciences

Contractile function of the cervix plays a role in normal and pathological pregnancy and parturition

(2020) Ourlad Alzeus G. Tantengco et al.   MEDICAL HYPOTHESES

Abnormal expression of connective tissue growth factor and its correlation with fibrogenesis in adenomyosis

(2020) Sha Wang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Effects of macrophage depletion on characteristics of cervix remodeling and pregnancy in CD11b-dtr mice

(2019) S M Yellon et al.   BIOLOGY OF REPRODUCTION

Lysyl oxidases: from enzyme activity to extracellular matrix cross-links

(2019) Sylvain D. Vallet et al.   Essays in Biochemistry

Mechanics of cervical remodelling: insights from rodent models of pregnancy

(2019) Kyoko Yoshida et al.   Interface Focus

Obesity associated advanced glycation end products within the human uterine cavity adversely impact endometrial function and embryo implantation competence

(2018) Gabriella S Antoniotti et al.   HUMAN REPRODUCTION

Mechanical and biochemical effects of progesterone on engineered cervical tissue

(2018) MICHAEL D HOUSE et al.   TISSUE ENGINEERING PART A

Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome

(2018) Chuyue Zhang et al.   HUMAN REPRODUCTION

Molecular characterization of lysyl oxidase-mediated extracellular matrix remodeling during mouse decidualization

(2017) Shu-Yun Li et al.   FEBS LETTERS

Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics

(2017) Md Soriful Islam et al.   HUMAN REPRODUCTION UPDATE

Tensile Mechanical Properties and Dynamic Collagen Fiber Re-Alignment of the Murine Cervix Are Dramatically Altered Throughout Pregnancy

(2017) Carrie E. Barnum et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue

(2017) Alfonso Gautieri et al.   MATRIX BIOLOGY

Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases

(2017) Marwa Kamel et al.   Biomed Research International

Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum

(2016) Friederike L. Jayes et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer

(2016) Philip C. Trackman   EXPERT OPINION ON THERAPEUTIC TARGETS

Corroborating evidence for platelet-induced epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the development of adenomyosis

(2016) Xishi Liu et al.   HUMAN REPRODUCTION

Collagen/elastin hydrogels cross-linked by squaric acid

(2016) J. Skopinska-Wisniewska et al.   Materials Science & Engineering C-Materials for Biological Applications

A systematic evaluation of collagen cross-links in the human cervix

(2015) Noelia M. Zork et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Expression of vascular endothelial factor-A, gelatinases (MMP-2, MMP-9) and TIMP-1 in uterine leiomyomas

(2015) Porfyrios Korompelis et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Dysregulation of Lysyl Oxidase Expression in Lesions and Endometrium of Women With Endometriosis

(2015) Lynnette A. Ruiz et al.   Reproductive Sciences

Cervical Collagen Network Remodeling in Normal Pregnancy and Disrupted Parturition inAntxr2Deficient Mice

(2014) Kyoko Yoshida et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Quantitative Evaluation of Collagen Crosslinks and Corresponding Tensile Mechanical Properties in Mouse Cervical Tissue during Normal Pregnancy

(2014) Kyoko Yoshida et al.   PLoS One

Nicotine treatment prolongs gestation and inhibits cervical ripening in pregnant rats

(2013) Jinying Yang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

746: The affect of parity on the distribution of collagen crosslinks in the human cervix

(2013) Noelia Zork et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

(2013) T. R. Cox et al.   CANCER RESEARCH

Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells

(2013) S. K. Halder et al.   HUMAN REPRODUCTION

Uterine Leiomyoma: Available Medical Treatments and New Possible Therapeutic Options

(2013) Md. Soriful Islam et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Anthrax Toxin Receptor 2 Functions in ECM Homeostasis of the Murine Reproductive Tract and Promotes MMP Activity

(2012) Claire V. Reeves et al.   PLoS One

Cervical remodeling in term and preterm birth: insights from an animal model

(2012) Mala Mahendroo   REPRODUCTION

Cervical Softening During Pregnancy: Regulated Changes in Collagen Cross-Linking and Composition of Matricellular Proteins in the Mouse1

(2011) Meredith L. Akins et al.   BIOLOGY OF REPRODUCTION

Single-nucleotide polymorphisms in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility

(2011) Lynnette A. Ruiz et al.   FERTILITY AND STERILITY

High-density fine-mapping of a chromosome 10q26 linkage peak suggests association between endometriosis and variants close to CYP2C19

(2011) Jodie N. Painter et al.   FERTILITY AND STERILITY

Effect of estradiol and transforming growth factor beta 1(TGF β 1) on expression of lysyl oxidase (LOX) in three-dimensional (3D) cocultures of human endometrium

(2011) H. Itoh et al.   FERTILITY AND STERILITY

Pharmacologic actions of progestins to inhibit cervical ripening and prevent delivery depend on their properties, the route of administration, and the vehicle

(2010) Ruben J. Kuon et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects

(2010) Begoña López et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Fox-2 protein regulates the alternative splicing of scleroderma-associated lysyl hydroxylase 2 messenger RNA

(2010) Puneet Seth et al.   ARTHRITIS AND RHEUMATISM

A Study of the Anisotropy and Tension/Compression Behavior of Human Cervical Tissue

(2010) Kristin M. Myers et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases

(2010) JeHoon Lee et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Collagen concentration and biomechanical properties of samples from the lower uterine cervix in relation to age and parity in non-pregnant women

(2010) Birgitte S Oxlund et al.   Reproductive Biology and Endocrinology

Deregulation of LOXL1 and HTRA1 Gene Expression in Endometriosis

(2010) Daniel Blassioli Dentillo et al.   Reproductive Sciences

Why Leiomyomas Are Called Fibroids: The Central Role of Extracellular Matrix in Symptomatic Women

(2010) Minnie Malik et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Cervical remodeling during pregnancy and parturition

(2010) Brenda Timmons et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Functional Consequences of Mitochondrial DNA Deletions in Human Skin Fibroblasts

(2009) Marc Majora et al.   AMERICAN JOURNAL OF PATHOLOGY

A Stiff Blow from the Stroma: Collagen Crosslinking Drives Tumor Progression

(2009) Mei Rosa Ng et al.   CANCER CELL

Collagens

(2009) Marion K. Gordon et al.   CELL AND TISSUE RESEARCH

Changes in the biochemical constituents and morphologic appearance of the human cervical stroma during pregnancy

(2009) Kristin Myers et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Cervical ripening and insufficiency: From biochemical and molecular studies to in vivo clinical examination

(2009) Dietmar Schlembach et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

The effect of bilateral pelvic neurectomy on cervical ripening in pregnant rats

(2009) Lynette B. Mackay et al.   JOURNAL OF PERINATAL MEDICINE

High-mobility group box protein 1 and its signalling receptors in human preterm and term cervix

(2009) Aurelija Dubicke et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus

(2009) M. Saito et al.   OSTEOPOROSIS INTERNATIONAL

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

Progress in matrix metalloproteinase research

(2008) G MURPHY et al.   MOLECULAR ASPECTS OF MEDICINE

Endometrial Gene Expression in Early Pregnancy: Lessons From Human Ectopic Pregnancy

(2008) Ricardo F. Savaris et al.   Reproductive Sciences

Medroxyprogesterone Acetate Modulates Remodeling, Immune Cell Census, and Nerve Fibers in the Cervix of a Mouse Model for Inflammation-induced Preterm Birth

(2008) Steven M. Yellon et al.   Reproductive Sciences