Biochemical characterization of spleen tyrosine kinase (SYK) isoforms in platelets

Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells

(2022) Vincent Denis et al.   PLoS One

Feedback Regulation of Syk by Protein Kinase C in Human Platelets

(2019) Stephanie Makhoul et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation

(2019) Joanne L. Dunster et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications

(2018) Giovanni Nassa et al.   Scientific Reports

TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK

(2017) Edina Schweighoffer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients

(2017) Robert R. J. Coebergh van den Braak et al.   PLoS One

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition

(2016) Florian Beck et al.   BLOOD

TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk

(2016) Kevin Reppschläger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression

(2016) Beibei Ni et al.   Oncology Letters

Anti–miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice

(2015) Yuhang Zhou et al.   BLOOD

 -Glucan-Activated Human B Lymphocytes Participate in Innate Immune Responses by Releasing Proinflammatory Cytokines and Stimulating Neutrophil Chemotaxis

(2015) M. F. Ali et al.   JOURNAL OF IMMUNOLOGY

Expression of Variant Isoforms of the Tyrosine Kinase SYK Determines the Prognosis of Hepatocellular Carcinoma

(2014) Jian Hong et al.   CANCER RESEARCH

Copy Number Analysis of the Murine Platelet Proteome Spanning the Complete Abundance Range

(2014) Marlis Zeiler et al.   MOLECULAR & CELLULAR PROTEOMICS

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Complex phosphorylation dynamics control the composition of the Syk interactome in B cells

(2011) Hanibal Bohnenberger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Alternative splicing of SYK regulates mitosis and cell survival

(2011) Panagiotis Prinos et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of Syk by Phosphorylation on Serine in the Linker Insert

(2010) Leela L. Paris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate

(2010) Xianwen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Platelet Receptor CLEC-2 Is Active as a Dimer

(2009) Aleksandra A. Watson et al.   BIOCHEMISTRY

Syk and pTyr'd: Signaling through the B cell antigen receptor

(2009) Robert L. Geahlen   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Signal-Dependent Protein Synthesis by Activated Platelets

(2008) Guy A. Zimmerman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TULA proteins regulate activity of the protein tyrosine kinase Syk

(2008) Rachana Agrawal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets

(2007) Kamala Bhavaraju et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phosphoproteome of Resting Human Platelets

(2007) René P. Zahedi et al.   JOURNAL OF PROTEOME RESEARCH