TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk

Platelet signaling: a complex interplay between inhibitory and activatory networks

(2016) A. P. Bye et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Anti–miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice

(2015) Yuhang Zhou et al.   BLOOD

Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach

(2015) Joanne L. Dunster et al.   PLoS Computational Biology

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness

(2015) Jing Zhang et al.   Stem Cell Reports

Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo

(2014) Tiffanny N Newman et al.   IMMUNOLOGY AND CELL BIOLOGY

Enhanced Response of T Cells from Murine Gammaherpesvirus 68-Infected Mice Lacking the Suppressor of T Cell Receptor Signaling Molecules Sts-1 and Sts-2

(2014) Brandon Cieniewicz et al.   PLoS One

Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants

(2013) Boris S. Luis et al.   FEBS Journal

Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker

(2013) Q. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function

(2012) Steven H. Back et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Once Phosphorylated, Tyrosines in Carboxyl Terminus of Protein-tyrosine Kinase Syk Interact with Signaling Proteins, Including TULA-2, a Negative Regulator of Mast Cell Degranulation

(2012) Rodrigo Orlandini de Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TULA-family proteins: A new class of cellular regulators

(2012) Alexander Y. Tsygankov   JOURNAL OF CELLULAR PHYSIOLOGY

Structural and Biophysical Characterization of the Syk Activation Switch

(2012) Ulrich Grädler et al.   JOURNAL OF MOLECULAR BIOLOGY

Complex phosphorylation dynamics control the composition of the Syk interactome in B cells

(2011) Hanibal Bohnenberger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sts-2 Is a Phosphatase That Negatively Regulates Zeta-associated Protein (ZAP)-70 and T Cell Receptor Signaling Pathways

(2011) Boris San Luis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets

(2010) D. H. Thomas et al.   BLOOD

Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate

(2010) Xianwen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosines in the Carboxyl Terminus Regulate Syk Kinase Activity and Function

(2010) Rodrigo O. de Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TULA-family proteins: an odd couple

(2009) Alexander Y. Tsygankov   CELLULAR AND MOLECULAR LIFE SCIENCES

The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development

(2008) Yogesh Kulathu et al.   EMBO JOURNAL

Multidomain STS/TULA proteins are novel cellular regulators

(2008) Alexander Y. Tsygankov   IUBMB LIFE

Molecular Mechanism of the Syk Activation Switch

(2008) Emily Tsang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TULA proteins regulate activity of the protein tyrosine kinase Syk

(2008) Rachana Agrawal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling

(2008) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion

(2007) Evgeniya V. Smirnova et al.   VIROLOGY