Effect of Food Viscosity on Drug Dissolution

Prediction of negative food effect induced by bile micelle binding on oral absorption of hydrophilic cationic drugs

(2020) Yoshiyuki Akiyama et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A reaction limited in vivo dissolution model for the study of drug absorption: Towards a new paradigm for the biopharmaceutic classification of drugs

(2018) Panos Macheras et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Regulatory Perspectives on Strength-Dependent Dissolution Profiles and Biowaiver Approaches for Immediate Release (IR) Oral Tablets in New Drug Applications

(2016) Sandra Suarez-Sharp et al.   AAPS Journal

Theoretical Analysis of Drug Dissolution: I. Solubility and Intrinsic Dissolution Rate

(2016) Boris Shekunov et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Coning phenomena under laminar flow

(2015) Mizuki Higuchi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Determination of Intrinsic Dissolution Rate Using Miniaturized Rotating and Stationary Disk Systems

(2014) Yin-Chao Tseng et al.   DISSOLUTION TECHNOLOGIES

Minimum rotation speed to prevent coning phenomena in compendium paddle dissolution apparatus

(2014) Mizuki Higuchi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Viscosity-mediated negative food effect on oral absorption of poorly-permeable drugs with an absorption window in the proximal intestine: In vitro experimental simulation and computational verification

(2014) Sandra Cvijić et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanistic Understanding of Food Effects: Water Diffusivity in Gastrointestinal Tract Is an Important Parameter for the Prediction of Disintegration of Solid Oral Dosage Forms

(2013) Asma Radwan et al.   MOLECULAR PHARMACEUTICS

Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity

(2012) Asma Radwan et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Bio-relevant media to assess drug permeability: Sodium taurocholate and lecithin combination or crude bile?

(2012) Katja Berginc et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The Use of Biorelevant Dissolution Media to Forecast the In Vivo Performance of a Drug

(2010) Sandra Klein   AAPS Journal

Profiling and Trend Analysis of Food Effects on Oral Drug Absorption Considering Micelle Interaction and Solubilization by Bile Micelles

(2010) Yukinori Kawai et al.   Drug Metabolism and Pharmacokinetics

Aqueous Boundary Layers Related to Oral Absorption of a Drug: From Dissolution of a Drug to Carrier Mediated Transport and Intestinal Wall Metabolism

(2010) Kiyohiko Sugano   MOLECULAR PHARMACEUTICS

Miniaturization of Powder Dissolution Measurement and Estimation of Particle Size

(2009) Alex Avdeef et al.   CHEMISTRY & BIODIVERSITY

Theoretical comparison of hydrodynamic diffusion layer models used for dissolution simulation in drug discovery and development

(2008) Kiyohiko Sugano   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Disintegration of Solid Foods in Human Stomach

(2008) F. Kong et al.   JOURNAL OF FOOD SCIENCE

Tablet disintegration and drug dissolution in viscous media: Paracetamol IR tablets

(2007) Jelena Parojčić et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a reaction-limited model of dissolution: Application to official dissolution tests experiments

(2007) A. Dokoumetzidis et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS