Direct investigation of cell contraction signal networks by light-based perturbation methods

Structural Biochemistry of Muscle Contraction

(2023) Zhexin Wang et al.   Annual Review of Biochemistry

Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases

(2023) Rocío G. Sampayo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Light-driven biological actuators to probe the rheology of 3D microtissues

(2023) Adrien Méry et al.   Nature Communications

Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination

(2022) Hanqing Guo et al.   eLife

A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4

(2022) Ani Michaud et al.   JOURNAL OF CELL BIOLOGY

Generation of stress fibers through myosin-driven reorganization of the actin cortex

(2021) Jaakko I Lehtimäki et al.   eLife

Single‐Component Optogenetic Tools for Inducible RhoA GTPase Signaling

(2021) Erin E. Berlew et al.   Advanced Biology

Monitoring the Response of Multiple Signal Network Components to Acute Chemo‐Optogenetic Perturbations in Living Cells

(2021) Manuela Kowalczyk et al.   CHEMBIOCHEM

Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair

(2021) Fernando R. Valencia et al.   DEVELOPMENTAL CELL

Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis

(2021) Kei Yamamoto et al.   Nature Communications

Actin Cell Cortex: Structure and Molecular Organization

(2020) Tatyana M. Svitkina   TRENDS IN CELL BIOLOGY

Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network

(2020) Dominic Kamps et al.   Cell Reports

Differential Expression of a Classic Cadherin Directs Tissue-Level Contractile Asymmetry during Neural Tube Closure

(2019) Hidehiko Hashimoto et al.   DEVELOPMENTAL CELL

Structure and regulation of human epithelial cell transforming 2 protein

(2019) Mengran Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploratory cell dynamics: a sense of touch for cells?

(2018) Perihan Nalbant et al.   BIOLOGICAL CHEMISTRY

Architecture shapes contractility in actomyosin networks

(2018) Gijsje H Koenderink et al.   CURRENT OPINION IN CELL BIOLOGY

Ordering of myosin II filaments driven by mechanical forces: experiments and theory

(2018) Kinjal Dasbiswas et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Muscle Contraction

(2018) H. Lee Sweeney et al.   Cold Spring Harbor Perspectives in Biology

A biochemical network controlling basal myosin oscillation

(2018) Xiang Qin et al.   Nature Communications

Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis

(2018) Emiliano Izquierdo et al.   Nature Communications

Adherens Junction Length during Tissue Contraction Is Controlled by the Mechanosensitive Activity of Actomyosin and Junctional Recycling

(2018) Angughali Sumi et al.   DEVELOPMENTAL CELL

Cytoplasmic flows in starfish oocytes are fully determined by cortical contractions

(2018) Nils Klughammer et al.   PLoS Computational Biology

Rho GTPases and actomyosin: Partners in regulating epithelial cell-cell junction structure and function

(2017) Torey R. Arnold et al.   EXPERIMENTAL CELL RESEARCH

An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns

(2017) Melanie Graessl et al.   JOURNAL OF CELL BIOLOGY

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments

(2017) Jordan R. Beach et al.   NATURE CELL BIOLOGY

Optogenetic control of cellular forces and mechanotransduction

(2017) Léo Valon et al.   Nature Communications

Mammalian Diaphanous 1 Mediates a Pathway for E-cadherin to Stabilize Epithelial Barriers through Junctional Contractility

(2017) Bipul R. Acharya et al.   Cell Reports

Controlling contractile instabilities in the actomyosin cortex

(2017) Masatoshi Nishikawa et al.   eLife

LOVTRAP: an optogenetic system for photoinduced protein dissociation

(2016) Hui Wang et al.   NATURE METHODS

Regulating Rho GTPases and their regulators

(2016) Richard G. Hodge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A self-organized biomechanical network drives shape changes during tissue morphogenesis

(2015) Akankshi Munjal et al.   NATURE

Activator–inhibitor coupling between Rho signalling and actin assembly makes the cell cortex an excitable medium

(2015) William M. Bement et al.   NATURE CELL BIOLOGY

Pulsatile cell-autonomous contractility drives compaction in the mouse embryo

(2015) Jean-Léon Maître et al.   NATURE CELL BIOLOGY

FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibers

(2014) N. Schulze et al.   JOURNAL OF CELL SCIENCE

Reversible protein inactivation by optogenetic trapping in cells

(2014) Sangkyu Lee et al.   NATURE METHODS

Localized light-induced protein dimerization in living cells using a photocaged dimerizer

(2014) Edward R. Ballister et al.   Nature Communications

Activated RhoA Is a Positive Feedback Regulator of the Lbc Family of Rho Guanine Nucleotide Exchange Factor Proteins

(2013) Frank Medina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monomeric α-catenin links cadherin to the actin cytoskeleton

(2013) Ridhdhi Desai et al.   NATURE CELL BIOLOGY

Molecular motors robustly drive active gels to a critically connected state

(2013) José Alvarado et al.   Nature Physics

Actin stress fibers - assembly, dynamics and biological roles

(2012) S. Tojkander et al.   JOURNAL OF CELL SCIENCE

TULIPs: tunable, light-controlled interacting protein tags for cell biology

(2012) Devin Strickland et al.   NATURE METHODS

Optical Control of Protein Activity by Fluorescent Protein Domains

(2012) X. X. Zhou et al.   SCIENCE

Life at the Leading Edge

(2011) Anne J. Ridley   CELL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

A role for actin arcs in the leading-edge advance of migrating cells

(2011) Dylan T. Burnette et al.   NATURE CELL BIOLOGY

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila

(2010) D. J. V. David et al.   DEVELOPMENT

Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure

(2010) G. B. Blanchard et al.   DEVELOPMENT

Integration of contractile forces during tissue invagination

(2010) Adam C. Martin et al.   JOURNAL OF CELL BIOLOGY

Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases

(2010) Chan-Soo Lee et al.   JOURNAL OF CELL BIOLOGY

A new lock-step mechanism of matrix remodelling based on subcellular contractile events

(2010) L. F. Castella et al.   JOURNAL OF CELL SCIENCE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

(2010) Michael Smutny et al.   NATURE CELL BIOLOGY

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Apical constriction: A cell shape change that can drive morphogenesis

(2009) Jacob M. Sawyer et al.   DEVELOPMENTAL BIOLOGY

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Morphogenetic movements driving neural tube closure in Xenopus require myosin IIB

(2008) Ana Rolo et al.   DEVELOPMENTAL BIOLOGY

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells

(2008) Ryu Takeya et al.   EMBO JOURNAL

Pulsed contractions of an actin–myosin network drive apical constriction

(2008) Adam C. Martin et al.   NATURE