An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns

Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement

(2017) Peter J. M. van Haastert et al.   MOLECULAR BIOLOGY OF THE CELL

Altering the threshold of an excitable signal transduction network changes cell migratory modes

(2017) Yuchuan Miao et al.   NATURE CELL BIOLOGY

Controlling contractile instabilities in the actomyosin cortex

(2017) Masatoshi Nishikawa et al.   eLife

Modular activation of Rho1 by GPCR signalling imparts polarized myosin II activation during morphogenesis

(2016) Stephen Kerridge et al.   NATURE CELL BIOLOGY

Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells

(2016) Nathalie R. Reinhard et al.   Scientific Reports

Locally excitable Cdc42 signals steer cells during chemotaxis

(2015) Hee Won Yang et al.   NATURE CELL BIOLOGY

Activator–inhibitor coupling between Rho signalling and actin assembly makes the cell cortex an excitable medium

(2015) William M. Bement et al.   NATURE CELL BIOLOGY

Differential Contributions of Nonmuscle Myosin II Isoforms and Functional Domains to Stress Fiber Mechanics

(2015) Ching-Wei Chang et al.   Scientific Reports

FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibers

(2014) N. Schulze et al.   JOURNAL OF CELL SCIENCE

Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis

(2014) Ming Tang et al.   Nature Communications

Activated RhoA Is a Positive Feedback Regulator of the Lbc Family of Rho Guanine Nucleotide Exchange Factor Proteins

(2013) Frank Medina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers

(2013) A. Schonichen et al.   JOURNAL OF CELL SCIENCE

Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations

(2013) Min Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Cooperative Interaction between Myosin II and Actin Cross-Linkers Mediated by Actin Filaments during Mechanosensation

(2012) Tianzhi Luo et al.   BIOPHYSICAL JOURNAL

Quantitative mapping of averaged focal adhesion dynamics in migrating cells by shape normalization

(2012) C. Mohl et al.   JOURNAL OF CELL SCIENCE

Signaling from the Living Plasma Membrane

(2011) Hernán E. Grecco et al.   CELL

Biased excitable networks: how cells direct motion in response to gradients

(2011) Pablo A Iglesias et al.   CURRENT OPINION IN CELL BIOLOGY

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

A role for actin arcs in the leading-edge advance of migrating cells

(2011) Dylan T. Burnette et al.   NATURE CELL BIOLOGY

Adhesive F-actin Waves: A Novel Integrin-Mediated Adhesion Complex Coupled to Ventral Actin Polymerization

(2011) Lindsay B. Case et al.   PLoS One

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation

(2010) Zhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases

(2010) Chan-Soo Lee et al.   JOURNAL OF CELL BIOLOGY

Cells navigate with a local-excitation, global-inhibition-biased excitable network

(2010) Y. Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells

(2008) Ryu Takeya et al.   EMBO JOURNAL

Rho Family GTPase Modification and Dependence on CAAXMotif-signaled Posttranslational Modification

(2008) Patrick J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Pulsed contractions of an actin–myosin network drive apical constriction

(2008) Adam C. Martin et al.   NATURE

A fast, robust and tunable synthetic gene oscillator

(2008) Jesse Stricker et al.   NATURE

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

(2008) Ina Poser et al.   NATURE METHODS