Co-expression of truncated and full-length tau induces severe neurotoxicity

The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties

(2015) Shin-Ei Matsumoto et al.   HUMAN MOLECULAR GENETICS

Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

(2015) Maxime Derisbourg et al.   Scientific Reports

Asparagine endopeptidase cleaves tau and promotes neurodegeneration

(2014) Hanna Rosenmann   NATURE MEDICINE

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

(2014) Zhentao Zhang et al.   NATURE MEDICINE

Tau promotes neurodegeneration through global chromatin relaxation

(2014) Bess Frost et al.   NATURE NEUROSCIENCE

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Characterization of tau oligomeric seeds in progressive supranuclear palsy

(2014) Julia E Gerson et al.   Acta Neuropathologica Communications

Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice

(2013) Florence Clavaguera et al.   ACTA NEUROPATHOLOGICA

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

(2013) Laura J. Blair et al.   JOURNAL OF CLINICAL INVESTIGATION

Tau pathology and neurodegeneration

(2013) Maria Grazia Spillantini et al.   LANCET NEUROLOGY

Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule Pathway

(2013) Christopher S. Brower et al.   MOLECULAR CELL

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

(2013) Usman A Khan et al.   NATURE NEUROSCIENCE

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

An Enzyme-Generated Fragment of Tau Measured in Serum Shows an Inverse Correlation to Cognitive Function

(2013) Kim Henriksen et al.   PLoS One

Biochemistry of Amyloid  -Protein and Amyloid Deposits in Alzheimer Disease

(2013) C. L. Masters et al.   Cold Spring Harbor Perspectives in Medicine

Formation and Propagation of Tau Oligomeric Seeds

(2013) Julia E. Gerson et al.   Frontiers in Neurology

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

(2012) Cristian A. Lasagna-Reeves et al.   FASEB JOURNAL

The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

(2012) B. Zhang et al.   JOURNAL OF NEUROSCIENCE

100 years of Lewy pathology

(2012) Michel Goedert et al.   Nature Reviews Neurology

Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain

(2011) Katherine J. Kopeikina et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of Prefibrillar Tau Oligomersin Vitroand in Alzheimer Disease

(2011) Kristina R. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats

(2011) Cao Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Are Tangles as Toxic as They Look?

(2011) Tara L. Spires-Jones et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Immunoelectron Microscopic and Biochemical Studies of Caspase-Cleaved Tau in a Mouse Model of Tauopathy

(2011) Wen-Lang Lin et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

First transgenic rat model developing progressive cortical neurofibrillary tangles

(2011) Peter Filipcik et al.   NEUROBIOLOGY OF AGING

Impaired muscle growth and response to insulin-like growth factor 1 in dysferlin-mediated muscular dystrophy

(2010) Alexis R. Demonbreun et al.   HUMAN MOLECULAR GENETICS

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Caspases first

(2010) Jesús Avila   Nature Reviews Neurology

Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport: Fig. 1

(2010) Keith A. Vossel et al.   SCIENCE

Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo

(2010) Vikram Khurana et al.   PLoS Genetics

Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43

(2009) Takashi Nonaka et al.   HUMAN MOLECULAR GENETICS

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Analysis of Tau Phosphorylation and Truncation in a Mouse Model of Human Tauopathy

(2007) Patrice Delobel et al.   AMERICAN JOURNAL OF PATHOLOGY