Asparagine endopeptidase cleaves tau and promotes neurodegeneration

A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes

(2014) Bo Zhang et al.   NATURE MEDICINE

“Prion-Like” Templated Misfolding in Tauopathies

(2013) Florence Clavaguera et al.   BRAIN PATHOLOGY

Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

(2013) Gustavo Basurto-Islas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

Asparaginyl endopeptidase cleaves TDP-43 in brain

(2012) Jeremy H. Herskowitz et al.   PROTEOMICS

Proteolytic processing of tau

(2010) Yipeng Wang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase

(2008) Zhixue Liu et al.   MOLECULAR CELL