Citral reduces breast tumor growth by inhibiting the cancer stem cell marker ALDH1A3

Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools

(2016) Nina Akrap et al.   Stem Cell Reports

Cellular Effect of Curcumin and Citral Combination on Breast Cancer Cells: Induction of Apoptosis and Cell Cycle Arrest

(2015) Pinaki B. Patel et al.   Journal of Breast Cancer

Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma

(2015) Lili Yue et al.   MELANOMA RESEARCH

Formulation, Characterization, and Antitumor Properties of Trans- and Cis-Citral in the 4T1 Breast Cancer Xenograft Mouse Model

(2015) San Zeng et al.   PHARMACEUTICAL RESEARCH

Cancer stem cell related markers of radioresistance in head and neck squamous cell carcinoma

(2015) Ina Kurth et al.   Oncotarget

A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations

(2015) Claudia Canino et al.   Oncotarget

Disulfiram inhibits TGF-β-induced epithelial-mesenchymal transition and stem-like features in breast cancer via ERK/NF-κB/Snail pathway

(2015) Dan Han et al.   Oncotarget

Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide

(2015) Joanna Triscott et al.   Oncotarget

Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo

(2015) Peng Liu et al.   Oncotarget

Combining Amine Metabolomics and Quantitative Proteomics of Cancer Cells Using Derivatization with Isobaric Tags

(2014) J. Patrick Murphy et al.   ANALYTICAL CHEMISTRY

The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation

(2014) D. Raha et al.   CANCER RESEARCH

Essential Role of Aldehyde Dehydrogenase 1A3 for the Maintenance of Non-Small Cell Lung Cancer Stem Cells Is Associated with the STAT3 Pathway

(2014) C. Shao et al.   CLINICAL CANCER RESEARCH

Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma

(2014) TRI BUDI HARTOMO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Prognostic significance of ALDH1A1-positive cancer stem cells in patients with locally advanced, metastasized head and neck squamous cell carcinoma

(2014) Xu Qian et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

(2014) Paola Marcato et al.   Molecular Oncology

Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts

(2014) Suling Liu et al.   Stem Cell Reports

Increased expression of ALDH1A1 protein is associated with poor prognosis in clear cell renal cell carcinoma

(2013) Kefeng Wang et al.   MEDICAL ONCOLOGY

ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma

(2013) Lang Yang et al.   MODERN PATHOLOGY

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells

(2012) P Liu et al.   BRITISH JOURNAL OF CANCER

Aldehyde Dehydrogenase 1A1 Possesses Stem-Like Properties and Predicts Lung Cancer Patient Outcome

(2012) Xiao Li et al.   Journal of Thoracic Oncology

ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets

(2012) Yuchun Luo et al.   STEM CELLS

The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance

(2011) Jan S. Moreb et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The aldehyde dehydrogenase enzyme 7A1 is functionally involved in prostate cancer bone metastasis

(2011) Christel van den Hoogen et al.   CLINICAL & EXPERIMENTAL METASTASIS

Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity and outcome to neoadjuvant chemotherapy

(2011) Thaer Khoury et al.   MODERN PATHOLOGY

Twist2 contributes to breast cancer progression by promoting an epithelial–mesenchymal transition and cancer stem-like cell self-renewal

(2011) X Fang et al.   ONCOGENE

Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways

(2010) Naoko Takebe et al.   Nature Reviews Clinical Oncology

Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of Metastasis

(2010) Paola Marcato et al.   STEM CELLS

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

Citral inhibits cell proliferation and induces apoptosis and cell cycle arrest in MCF-7 cells

(2009) Wahid Chaouki et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Cancer Stem Cells Contribute to Cisplatin Resistance in Brca1/p53-Mediated Mouse Mammary Tumors

(2008) N. Shafee et al.   CANCER RESEARCH