Autophagy inhibition upregulates CD4+ tumor infiltrating lymphocyte expression via miR-155 regulation and TRAIL activation

Lung Cancer Screening

(2015) Lynn T. Tanoue et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia

(2015) Xian Zeng et al.   Autophagy

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

(2015) Jun He et al.   Autophagy

Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis

(2015) Jian Wen et al.   BREAST CANCER RESEARCH AND TREATMENT

Autophagy contributes to the enrichment and survival of colorectal cancer stem cells under oxaliplatin treatment

(2015) Hao-Zheng Yang et al.   CANCER LETTERS

Predictive biomarkers in PD-1/PD-L1 checkpoint blockade immunotherapy

(2015) Xiangjiao Meng et al.   CANCER TREATMENT REVIEWS

MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells

(2015) Paul Zarogoulidis et al.   CELLULAR SIGNALLING

Tumor suppressor miR-34a targets PD-L1 and functions as a potential immunotherapeutic target in acute myeloid leukemia

(2015) Xi Wang et al.   CELLULAR SIGNALLING

The prognostic value of PD-L1 expression for non-small cell lung cancer patients: A meta-analysis

(2015) A. Wang et al.   EJSO

The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung Cancer

(2015) Yu Fujita et al.   MOLECULAR THERAPY

Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth

(2015) Jonathan Lévy et al.   NATURE CELL BIOLOGY

Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway

(2015) Kim C. Ohaegbulam et al.   TRENDS IN MOLECULAR MEDICINE

Inhibition of autophagy by bafilomycin A1 promotes chemosensitivity of gastric cancer cells

(2015) Liang-qing Li et al.   TUMOR BIOLOGY

miR-155, identified as anti-metastatic by global miRNA profiling of a metastasis model, inhibits cancer cell extravasation and colonization in vivo and causes significant signaling alterations

(2015) Karina G. Thomsen et al.   Oncotarget

Autophagy-mediated regulation of macrophages and its applications for cancer

(2014) Peiwen Chen et al.   Autophagy

Autophagy: An adaptive metabolic response to stress shaping the antitumor immunity

(2014) Elodie Viry et al.   BIOCHEMICAL PHARMACOLOGY

Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

(2014) Katharina Leithner et al.   BMC CANCER

Tumor-infiltrating CD8+ and FOXP3+ lymphocytes in triple-negative breast cancer: its correlation with pathological complete response to neoadjuvant chemotherapy

(2014) Minoru Miyashita et al.   BREAST CANCER RESEARCH AND TREATMENT

PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients

(2014) A D'Incecco et al.   BRITISH JOURNAL OF CANCER

Autophagy modulation: a target for cancer treatment development

(2014) Alison Duffy et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Blockade of the B7-H1/PD-1 Pathway as a Basis for Combination Anticancer Therapy

(2014) Mario Sznol   CANCER JOURNAL

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs

(2014) Feng Wang et al.   CURRENT PHARMACEUTICAL DESIGN

Exploring the potential of immuno-oncology-based treatment for patients with non-small cell lung cancer

(2014) David Heigener et al.   Expert Review of Anticancer Therapy

Autophagy in T-cell development, activation and differentiation

(2014) Alisha W Bronietzki et al.   IMMUNOLOGY AND CELL BIOLOGY

Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy

(2014) Kim A Reiss et al.   Immunotherapy

MicroRNA-513 Regulates B7-H1 Translation and Is Involved in IFN- -Induced B7-H1 Expression in Cholangiocytes

(2014) A.-Y. Gong et al.   JOURNAL OF IMMUNOLOGY

Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Solid Tumors: A Systematic Review and Meta-Analysis

(2014) Arnoud J. Templeton et al.   JNCI-Journal of the National Cancer Institute

Clinically relevant determinants of body composition, function and nutritional status as mortality predictors in lung cancer patients

(2014) Miroslav Kovarik et al.   LUNG CANCER

Tumor Antigen-Specific Monoclonal Antibodies and Induction of T-Cell Immunity

(2014) Sumita Trivedi et al.   SEMINARS IN ONCOLOGY

PD-1 as an emerging therapeutic target in renal cell carcinoma: current evidence

(2014) Scott Tykodi   OncoTargets and Therapy

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

(2014) Limo Chen et al.   Nature Communications

Tumor-Infiltrating γδ T Lymphocytes: Pathogenic Role, Clinical Significance, and Differential Programing in the Tumor Microenvironment

(2014) Elena Lo Presti et al.   Frontiers in Immunology

The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer

(2013) Graeme J.K. Guthrie et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma

(2013) Weipeng Wang et al.   HUMAN GENETICS

TIM-4 Glycoprotein-Mediated Degradation of Dying Tumor Cells by Autophagy Leads to Reduced Antigen Presentation and Increased Immune Tolerance

(2013) Muhammad Baghdadi et al.   IMMUNITY

Risk factors and survival outcome for non-elective referral in non-small cell lung cancer patients – Analysis based on the National Lung Cancer Audit

(2013) P. Beckett et al.   LUNG CANCER

Potential diagnostic value of miR-155 in serum from lung adenocarcinoma patients

(2013) FENG GAO et al.   ONCOLOGY REPORTS

Targeting autophagy as a potential therapeutic approach for melanoma therapy

(2013) He Liu et al.   SEMINARS IN CANCER BIOLOGY

Autophagy regulation and its role in cancer

(2013) Séverine Lorin et al.   SEMINARS IN CANCER BIOLOGY

IL-17A is produced by breast cancer TILs and promotes chemoresistance and proliferation through ERK1/2

(2013) Stéphanie Cochaud et al.   Scientific Reports

Tumor microenvironment and lymphocyte infiltration

(2012) Gwendoline Rahir et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Autophagy in tumorigenesis and cancer therapy: Dr. Jekyll or Mr. Hyde?

(2012) Shengtao Zhou et al.   CANCER LETTERS

The Prognostic Value of FoxP3+ Tumor-Infiltrating Lymphocytes in Cancer: A Critical Review of the Literature

(2012) R. J. deLeeuw et al.   CLINICAL CANCER RESEARCH

Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer

(2012) Rin Yamaguchi et al.   HUMAN PATHOLOGY

Pharmacogenetics of conventional chemotherapy in non-small-cell lung cancer: a changing landscape?

(2012) Elisa Giovannetti et al.   PHARMACOGENOMICS

MiRNA in innate immune responses: novel players in wound inflammation

(2010) Sashwati Roy et al.   PHYSIOLOGICAL GENOMICS

Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells

(2009) Jianrui Song et al.   Autophagy