Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

Commentary: locating the restriction point

(2023) Robert F. Brooks   Cell Division

Cell cycle inertia underlies a bifurcation in cell fates after DNA damage

(2021) Jenny F. Nathans et al.   Science Advances

Cell Cycle Commitment and the Origins of Cell Cycle Variability

(2021) Robert F. Brooks   Frontiers in Cell and Developmental Biology

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

(2020) Nadia Hégarat et al.   EMBO JOURNAL

Temporal integration of mitogen history in mother cells controls proliferation of daughter cells

(2020) Mingwei Min et al.   SCIENCE

Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle

(2020) Michael L. Zhao et al.   Cell Reports

Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1

(2019) Mingyu Chung et al.   MOLECULAR CELL

A Precise Cdk Activity Threshold Determines Passage through the Restriction Point

(2018) Clayton Schwarz et al.   MOLECULAR CELL

Irreversible APC Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry

(2016) Steven D. Cappell et al.   CELL

Quantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysis

(2016) J. A. Cornwell et al.   Scientific Reports

Necessary and Sufficient Role for a Mitosis Skip in Senescence Induction

(2014) Yoshikazu Johmura et al.   MOLECULAR CELL

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

An integrated view of cyclin E function and regulation

(2012) Ka Tat Siu et al.   CELL CYCLE

Origin of bistability underlying mammalian cell cycle entry

(2011) G. Yao et al.   Molecular Systems Biology

Temporal competition between differentiation programs determines cell fate choice

(2011) A. Kuchina et al.   Molecular Systems Biology

p53- and p21-dependent premature APC/C–Cdh1 activation in G2 is part of the long-term response to genotoxic stress

(2010) L Wiebusch et al.   ONCOGENE

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

A bistable Rb–E2F switch underlies the restriction point

(2008) Guang Yao et al.   NATURE CELL BIOLOGY