MicroRNA-Mediated Reprogramming of Somatic Cells into Neural Stem Cells or Neurons

MicroRNA abundance is altered in synaptoneurosomes during prion disease

(2016) Amrit S. Boese et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A decade of transcription factor-mediated reprogramming to pluripotency

(2016) Kazutoshi Takahashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation

(2016) Jamie O. Brett et al.   Aging-US

LIN28: roles and regulation in development and beyond

(2015) J. Tsialikas et al.   DEVELOPMENT

Induction of Pluripotency in Astrocytes through a Neural Stem Cell-like State

(2015) May Nakajima-Koyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical role of the miR-200 family in regulating differentiation and proliferation of neurons

(2015) Ankita Pandey et al.   JOURNAL OF NEUROCHEMISTRY

The Dlx5 and Foxg1 transcription factors, linked via miRNA-9 and -200, are required for the development of the olfactory and GnRH system

(2015) Giulia Garaffo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

MicroRNA 302/367Cluster Effectively Facilitates Direct Reprogramming from Human Fibroblasts into Functional Neurons

(2015) Chen Zhou et al.   STEM CELLS AND DEVELOPMENT

Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma

(2015) Min Zheng et al.   Oncotarget

MicroRNA-302/367 Cluster Governs hESC Self-Renewal by Dually Regulating Cell Cycle and Apoptosis Pathways

(2015) Zhonghui Zhang et al.   Stem Cell Reports

SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain

(2015) Wenze Niu et al.   Stem Cell Reports

MicroRNA-Mediated In Vitro and In Vivo Direct Conversion of Astrocytes to Neuroblasts

(2015) Maryam Ghasemi-Kasman et al.   PLoS One

MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1

(2015) Ariel Bier et al.   Oncotarget

MicroRNA binding sites in the coding region of mRNAs: Extending the repertoire of post-transcriptional gene regulation

(2014) Anneke Brümmer et al.   BIOESSAYS

Generation of Multipotent Induced Neural Crest by Direct Reprogramming of Human Postnatal Fibroblasts with a Single Transcription Factor

(2014) Yong Jun Kim et al.   Cell Stem Cell

Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

(2014) Ke Li et al.   Cell Stem Cell

miR379-410 cluster miRNAs regulate neurogenesis and neuronal migration by fine-tuning N-cadherin

(2014) L. Rago et al.   EMBO JOURNAL

Direct Conversion of Human Fibroblasts into Neuronal Restricted Progenitors

(2014) Qingjian Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-134 Regulates Ischemia/Reperfusion Injury-Induced Neuronal Cell Death by Regulating CREB Signaling

(2014) Weidong Huang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Small molecules facilitate rapid and synchronous iPSC generation

(2014) Ori Bar-Nur et al.   NATURE METHODS

Direct conversion of mouse fibroblasts into induced neural stem cells

(2014) Sung Min Kim et al.   Nature Protocols

Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B

(2014) W. Chi et al.   NEUROSCIENCE

Understanding principles of miRNA target recognition and function through integrated biological and bioinformatics approaches

(2014) Adam P. Carroll et al.   Wiley Interdisciplinary Reviews-RNA

MicroRNA-9 controls dendritic development by targeting REST

(2014) Sebastian A Giusti et al.   eLife

Mechanisms of miRNA-Mediated Gene Regulation from Common Downregulation to mRNA-Specific Upregulation

(2014) Ayla Valinezhad Orang et al.   International Journal of Genomics

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

(2014) Juli J. Unternaehrer et al.   Stem Cell Reports

MicroRNAs in pluripotency, reprogramming and cell fate induction

(2013) Patrick Lüningschrör et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Conserved miR-8/miR-200 Defines a Glial Niche that Controls Neuroepithelial Expansion and Neuroblast Transition

(2013) Javier Morante et al.   DEVELOPMENTAL CELL

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A

(2013) Kristina Althoff et al.   INTERNATIONAL JOURNAL OF CANCER

Scratch2 Prevents Cell Cycle Re-Entry by Repressing miR-25 in Postmitotic Primary Neurons

(2013) E. Rodriguez-Aznar et al.   JOURNAL OF NEUROSCIENCE

MicroRNAs as Neuronal Fate Determinants

(2013) Malin Åkerblom et al.   NEUROSCIENTIST

Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns

(2013) Siti Razila Abdul Razak et al.   PLoS One

Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation

(2013) G. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in regulation of pluripotency and somatic cell reprogramming

(2013) Tian Wang et al.   RNA Biology

miR-9: a versatile regulator of neurogenesis

(2013) Marion Coolen et al.   Frontiers in Cellular Neuroscience

Modulation of epigenetic regulators and cell fate decisions by miRNAs

(2013) Andreas J Gruber et al.   Epigenomics

Toward pluripotency by reprogramming: mechanisms and application

(2013) Tao Wang et al.   Protein & Cell

microRNAs as novel regulators of stem cell pluripotency and somatic cell reprogramming

(2012) Meng Amy Li et al.   BIOESSAYS

Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors

(2012) Dong Wook Han et al.   Cell Stem Cell

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

(2012) Karen L. Ring et al.   Cell Stem Cell

Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons

(2012) Y. M. Clovis et al.   DEVELOPMENT

MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain

(2012) Siok-Lay Tan et al.   GENES TO CELLS

MicroRNA-mediated somatic cell reprogramming

(2012) Chih-Hao Kuo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Locked Nucleic Acid-BasedIn SituHybridisation Reveals miR-7a as a Hypothalamus-Enriched MicroRNA with a Distinct Expression Pattern

(2012) S. Herzer et al.   JOURNAL OF NEUROENDOCRINOLOGY

MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant

(2012) M. Akerblom et al.   JOURNAL OF NEUROSCIENCE

A Unilateral Negative Feedback Loop Between miR-200 microRNAs and Sox2/E2F3 Controls Neural Progenitor Cell-Cycle Exit and Differentiation

(2012) C. Peng et al.   JOURNAL OF NEUROSCIENCE

Vitamin C improves the quality of somatic cell reprogramming

(2012) Miguel A Esteban et al.   NATURE GENETICS

miR-7a regulation of Pax6 controls spatial origin of forebrain dopaminergic neurons

(2012) Antoine de Chevigny et al.   NATURE NEUROSCIENCE

A novel role of miR-302/367 in reprogramming

(2011) Chih-Hao Kuo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mirtrons: microRNA biogenesis via splicing

(2011) Jakub O. Westholm et al.   BIOCHIMIE

Molecular Basis for Interaction of let-7 MicroRNAs with Lin28

(2011) Yunsun Nam et al.   CELL

Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

(2011) Rajesh Ambasudhan et al.   Cell Stem Cell

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

(2011) Frederick Anokye-Danso et al.   Cell Stem Cell

Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs

(2011) Norikatsu Miyoshi et al.   Cell Stem Cell

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Stage-Specific Modulation of Cortical Neuronal Development by Mmu-miR-134

(2011) Philip Gaughwin et al.   CEREBRAL CORTEX

MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis

(2011) Boyan Bonev et al.   DEVELOPMENTAL CELL

Small RNA-mediated regulation of iPS cell generation

(2011) Zhonghan Li et al.   EMBO JOURNAL

MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition

(2011) Baojian Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-9 Regulates Neurogenesis in Mouse Telencephalon by Targeting Multiple Transcription Factors

(2011) M. Shibata et al.   JOURNAL OF NEUROSCIENCE

MicroRNA miR-9 Modifies Motor Neuron Columns by a Tuning Regulation of FoxP1 Levels in Developing Spinal Cords

(2011) G. Otaegi et al.   JOURNAL OF NEUROSCIENCE

Role of microRNAs in central nervous system development and pathology

(2011) Karla F. Meza-Sosa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

MicroRNA-mediated conversion of human fibroblasts to neurons

(2011) Andrew S. Yoo et al.   NATURE

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

(2011) Deepa Subramanyam et al.   NATURE BIOTECHNOLOGY

miR-34 miRNAs provide a barrier for somatic cell reprogramming

(2011) Yong Jin Choi et al.   NATURE CELL BIOLOGY

Direct reprogramming of mouse fibroblasts to neural progenitors

(2011) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-9

(2011) Yeliz Yuva-Aydemir et al.   RNA Biology

Brief Report: Combined Chemical Treatment Enables Oct4-Induced Reprogramming from Mouse Embryonic Fibroblasts

(2011) Xu Yuan et al.   STEM CELLS

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

(2011) GuoQiang Sun et al.   Nature Communications

MicroRNA miR-302 Inhibits the Tumorigenecity of Human Pluripotent Stem Cells by Coordinate Suppression of the CDK2 and CDK4/6 Cell Cycle Pathways

(2010) S.-L. Lin et al.   CANCER RESEARCH

Epigenetic Silencing of miR-137 Is an Early Event in Colorectal Carcinogenesis

(2010) F. Balaguer et al.   CANCER RESEARCH

MicroRNA-9 Coordinates Proliferation and Migration of Human Embryonic Stem Cell-Derived Neural Progenitors

(2010) Celine Delaloy et al.   Cell Stem Cell

A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation

(2010) Alessandro Rosa et al.   EMBO JOURNAL

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

(2010) Carolina Tarantino et al.   FASEB JOURNAL

miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells

(2010) Ming Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Developmentally regulated expression of Sox9 and microRNAs 124,128 and 23 in neuroepithelial stem cells in the developing spinal cord

(2010) Barbara C. Farrell et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

(2010) Keith E. Szulwach et al.   JOURNAL OF CELL BIOLOGY

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

(2010) Collin Melton et al.   NATURE

Roles of small regulatory RNAs in determining neuronal identity

(2010) Xuekun Li et al.   NATURE REVIEWS NEUROSCIENCE

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation

(2010) Pietro Laneve et al.   NUCLEIC ACIDS RESEARCH

Regulation of somatic cell reprogramming through inducible mir-302 expression

(2010) Shi-Lung Lin et al.   NUCLEIC ACIDS RESEARCH

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb-1

(2010) Richard D. Smrt et al.   STEM CELLS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

FoxO3 Regulates Neural Stem Cell Homeostasis

(2009) Valérie M. Renault et al.   Cell Stem Cell

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

(2009) Justin K. Ichida et al.   Cell Stem Cell

The miR-430/427/302 Family Controls Mesendodermal Fate Specification via Species-Specific Target Selection

(2009) Alessandro Rosa et al.   DEVELOPMENTAL CELL

The miR-106b-25 Polycistron, Activated by Genomic Amplification, Functions as an Oncogene by Suppressing p21 and Bim

(2009) Takatsugu Kan et al.   GASTROENTEROLOGY

New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites

(2009) I. Lee et al.   GENOME RESEARCH

Sox2 roles in neural stem cells

(2009) Larysa H. Pevny et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease

(2009) A. N. Packer et al.   JOURNAL OF NEUROSCIENCE

MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells

(2009) Jiaqiang Ren et al.   Journal of Translational Medicine

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

(2009) David N. Ciccone et al.   NATURE

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

miR-9 and TLX: chasing tails in neural stem cells

(2009) Ahmet M Denli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

(2009) Chunnian Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Promotion of embryonic cortico-cerebral neuronogenesis by miR-124

(2009) Nicola Maiorano et al.   Neural Development

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines

(2008) L. T. Bemis et al.   CANCER RESEARCH

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

The role of Sox9 in prostate development

(2008) Martin K. Thomsen et al.   DIFFERENTIATION

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

(2008) Jenn-Yah Yu et al.   EXPERIMENTAL CELL RESEARCH

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller Glial cell development

(2008) Ross A. Poché et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Oct4/Sox2-Regulated miR-302 Targets Cyclin D1 in Human Embryonic Stem Cells

(2008) D. A. Greer Card et al.   MOLECULAR AND CELLULAR BIOLOGY

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary

(2008) Christoph Leucht et al.   NATURE NEUROSCIENCE

Generation of human-induced pluripotent stem cells

(2008) In-Hyun Park et al.   Nature Protocols

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

(2008) Lasse Sinkkonen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Members of the miRNA-200 Family Regulate Olfactory Neurogenesis

(2008) Philip S. Choi et al.   NEURON

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

MicroRNA-134 Modulates the Differentiation of Mouse Embryonic Stem Cells, Where It Causes Post-Transcriptional Attenuation of Nanog and LRH1

(2007) Yvonne M.-S. Tay et al.   STEM CELLS