Epitope editing enables targeted immunotherapy of acute myeloid leukaemia
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia
Authors
Keywords
-
Journal
NATURE
Volume 621, Issue 7978, Pages 404-414
Publisher
Springer Science and Business Media LLC
Online
2023-08-31
DOI
10.1038/s41586-023-06496-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD
- (2023) Niannian Xue et al. Nature Communications
- Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia
- (2023) Matteo Maria Naldini et al. Nature Communications
- Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells
- (2022) Samuele Ferrari et al. Cell Stem Cell
- Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome
- (2021) Valentina Vavassori et al. EMBO Molecular Medicine
- Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells
- (2021) Norman F. Russkamp et al. EXPERIMENTAL HEMATOLOGY
- Acute myeloid leukemia: current progress and future directions
- (2021) Hagop Kantarjian et al. Blood Cancer Journal
- Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
- (2021) Mitchell L. Leibowitz et al. NATURE GENETICS
- Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity
- (2021) Jianan Li et al. Nature Communications
- Immunotherapy in Acute Myeloid Leukemia: Where We Stand
- (2021) Alessandro Isidori et al. Frontiers in Oncology
- Catalytically Enhanced Cas9 Through Directed Protein Evolution
- (2021) Travis H. Hand et al. CRISPR Journal
- BAR-Seq clonal tracking of gene-edited cells
- (2021) Samuele Ferrari et al. Nature Protocols
- Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia
- (2021) Nadia El Khawanky et al. Nature Communications
- Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal
- (2020) Claudio Lo Giudice et al. Nature Protocols
- Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells
- (2020) Renier Myburgh et al. LEUKEMIA
- Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking
- (2020) Samuele Ferrari et al. NATURE BIOTECHNOLOGY
- Overexpression of CD200 and CD123 is a major influential factor in the clinical course of pediatric acute myeloid leukemia
- (2020) Eman Z. Kandeel et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
- (2019) Giulia Schiroli et al. Cell Stem Cell
- Gene-edited stem cells enable CD33-directed immune therapy for myeloid malignancies
- (2019) Florence Borot et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chimeric Antigen Receptor (CAR) T Cell Therapy in Acute Myeloid Leukemia (AML)
- (2019) Susanne Hofmann et al. Journal of Clinical Medicine
- Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia
- (2018) Miriam Y. Kim et al. CELL
- Precision therapy for acute myeloid leukemia
- (2018) Xue Yang et al. Journal of Hematology & Oncology
- CAR T-cells targeting FLT3 have potent activity against FLT3−ITD+ AML and act synergistically with the FLT3-inhibitor crenolanib
- (2018) Hardikkumar Jetani et al. LEUKEMIA
- Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML
- (2018) S. Haubner et al. LEUKEMIA
- CRISPR/Cas9 genome editing in human hematopoietic stem cells
- (2018) Rasmus O Bak et al. Nature Protocols
- A Flow Cytometry‐Based Assay for High‐Throughput Detection and Quantification of Neutrophil Extracellular Traps in Mixed Cell Populations
- (2018) Olga Zharkova et al. CYTOMETRY PART A
- CD123 expression levels in 846 acute leukemia patients based on standardized immunophenotyping
- (2018) Anne E. Bras et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- Engineering resistance to CD33-targeted immunotherapy in normal hematopoiesis by CRISPR/Cas9-deletion of CD33 exon 2
- (2018) Olivier Humbert et al. LEUKEMIA
- Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing
- (2018) Mehmet Fatih Bolukbasi et al. Nature Communications
- Targeting FLT3 by chimeric antigen receptor T cells for the treatment of acute myeloid leukemia
- (2017) L Chen et al. LEUKEMIA
- multiplierz v2.0: A Python-based ecosystem for shared access and analysis of native mass spectrometry data
- (2017) William M. Alexander et al. PROTEOMICS
- Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
- (2017) Jose Perdomo et al. Jove-Journal of Visualized Experiments
- In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases
- (2016) Luca Biasco et al. Cell Stem Cell
- CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
- (2016) Elad Jacoby et al. Nature Communications
- Catch me if you can: Leukemia Escape after CD19-Directed T Cell Immunotherapies
- (2016) Marco Ruella et al. Computational and Structural Biotechnology Journal
- CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia
- (2015) S S Kenderian et al. LEUKEMIA
- Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
- (2015) E. Sotillo et al. Cancer Discovery
- High Expression of c-kit mRNA Predicts Unfavorable Outcome in Adult Patients with t(8;21) Acute Myeloid Leukemia
- (2015) Xiaoning Gao et al. PLoS One
- Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells
- (2014) S. Gill et al. BLOOD
- Targeted genome editing in human repopulating haematopoietic stem cells
- (2014) Pietro Genovese et al. NATURE
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody
- (2014) Sophie E. Broughton et al. Cell Reports
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
- (2013) Stephan A. Grupp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region
- (2013) A. V. Reshetnyak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
- (2013) R. J. Brentjens et al. Science Translational Medicine
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
- (2012) N. Cieri et al. BLOOD
- Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia
- (2012) M Hofmann et al. LEUKEMIA
- Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical Implications
- (2012) Johan Lennartsson et al. PHYSIOLOGICAL REVIEWS
- A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells
- (2011) X. Wang et al. BLOOD
- Online Nanoflow Multidimensional Fractionation for High Efficiency Phosphopeptide Analysis
- (2011) Scott B. Ficarro et al. MOLECULAR & CELLULAR PROTEOMICS
- Gamma-1-Syntrophin Mediates Trafficking of Gamma-Enolase towards the Plasma Membrane and Enhances Its Neurotrophic Activity
- (2011) Anja Hafner et al. NEUROSIGNALS
- A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting
- (2010) Markus Kügler et al. BRITISH JOURNAL OF HAEMATOLOGY
- Improved Electrospray Ionization Efficiency Compensates for Diminished Chromatographic Resolution and Enables Proteomics Analysis of Tyrosine Signaling in Embryonic Stem Cells
- (2009) Scott B. Ficarro et al. ANALYTICAL CHEMISTRY
- Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation
- (2009) Luca Vago et al. NEW ENGLAND JOURNAL OF MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now