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Bioorthogonal Disassembly of Hierarchical DNAzyme Nanogel for High-Performance Intracellular microRNA Imaging

(2023) Jinhua Shang et al.   Nano Letters

Bioinspired magnetic nanocomplexes amplifying STING activation of tumor-associated macrophages to potentiate cancer immunotherapy

(2022) Tianliang Li et al.   Nano Today

Copackaging photosensitizer and PD-L1 siRNA in a nucleic acid nanogel for synergistic cancer photoimmunotherapy

(2022) Yuanyuan Guo et al.   Science Advances

Programmable Assembly of Multivalent DNA‐Protein Superstructures for Tumor Imaging and Targeted Therapy

(2022) Zhen Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in the biological mechanism and application of manganese-based nanoformulations for enhanced immunotherapy

(2022) Xi Chen et al.   Nano Today

Self‐Activatable Photo‐Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy

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A self‐catabolic multifunctional DNAzyme nanosponge for programmable drug delivery and efficient gene silencing

(2021) Jing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifunctional biomolecule nanostructures for cancer therapy

(2021) Jing Wang et al.   Nature Reviews Materials

Precise Subcellular Organelle Targeting for Boosting Endogenous‐Stimuli‐Mediated Tumor Therapy

(2021) Wenyao Zhen et al.   ADVANCED MATERIALS

A DNA Nanocomplex Containing Cascade DNAzymes and Promoter‐Like Zn‐Mn‐Ferrite for Combined Gene/Chemo‐dynamic Therapy

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Amplifying STING activation by cyclic dinucleotide–manganese particles for local and systemic cancer metalloimmunotherapy

(2021) Xiaoqi Sun et al.   Nature Nanotechnology

Double Rolling Circle Amplification Generates Physically Cross-Linked DNA Network for Stem Cell Fishing

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Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity

(2020) Lin Hou et al.   ACS Nano

Engineering Polymeric Prodrug Nanoplatform for Vaccination Immunotherapy of Cancer

(2020) Lei Zhou et al.   NANO LETTERS

cGAS-STING–mediated DNA sensing maintains CD8+ T cell stemness and promotes antitumor T cell therapy

(2020) Wenwen Li et al.   Science Translational Medicine

Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel

(2020) Feihu Wang et al.   Nature Biomedical Engineering

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

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A DNA nanodevice-based vaccine for cancer immunotherapy

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Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

(2020) Leila Motedayen Aval et al.   Journal of Clinical Medicine

Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy

(2019) Daniel Shae et al.   Nature Nanotechnology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

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Nonviolent Self-Catabolic DNAzyme Nanosponges for Smart Anticancer Drug Delivery

(2019) Jing Wang et al.   ACS Nano

Advances in cancer immunotherapy 2019 – latest trends

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Responsive Exosome Nano-bioconjugates for Synergistic Cancer Therapy

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Programming DNA Nanoassembly for Enhanced Photodynamic Therapy

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Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

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Understanding the tumor immune microenvironment (TIME) for effective therapy

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T Cell–Inflamed versus Non-T Cell–Inflamed Tumors: A Conceptual Framework for Cancer Immunotherapy Drug Development and Combination Therapy Selection

(2018) Jonathan A. Trujillo et al.   Cancer Immunology Research

Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

(2018) Assaf Marcus et al.   IMMUNITY

cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response

(2017) Debojit Bose   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytoplasmic chromatin triggers inflammation in senescence and cancer

(2017) Zhixun Dou et al.   NATURE

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

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Aptamers as targeted therapeutics: current potential and challenges

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Tumour-infiltrating CD4+ and CD8+ lymphocytes as predictors of clinical outcome in glioma

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Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

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Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

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Reduced Naive CD4 T Cell Numbers and Impaired Induction of CD27 in Response to T Cell Receptor Stimulation Reflect a State of Immune Activation in Chronic Hepatitis C Virus Infection

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Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

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