Suppression of a deletion mutation in the gene encoding essential PBP2b reveals a new lytic transglycosylase involved in peripheral peptidoglycan synthesis inStreptococcus pneumoniaeD39

Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Streptococcus pneumoniae D39

(2015) Ozden Kocaoglu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Escherichia coli Strain DC2

(2015) Ozden Kocaoglu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Minimal Peptidoglycan (PG) Turnover in Wild-Type and PG Hydrolase and Cell Division Mutants of Streptococcus pneumoniae D39 Growing Planktonically and in Host-Relevant Biofilms

(2015) Michael J. Boersma et al.   JOURNAL OF BACTERIOLOGY

Transfer of penicillin resistance fromStreptococcus oralistoStreptococcus pneumoniaeidentifiesmurEas resistance determinant

(2015) Katya Todorova et al.   MOLECULAR MICROBIOLOGY

Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria

(2015) Rachel Yunck et al.   MOLECULAR MICROBIOLOGY

Activities and regulation of peptidoglycan synthases

(2015) Alexander J. F. Egan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mechanism of β-Lactam Action in Streptococcus pneumoniae: the Piperacillin Paradox

(2014) Jules Philippe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacterial cell division proteins as antibiotic targets

(2014) Tanneke den Blaauwen et al.   BIOORGANIC CHEMISTRY

Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery

(2014) Hongbaek Cho et al.   CELL

The Elongation of Ovococci

(2014) Jules Philippe et al.   Microbial Drug Resistance

The function of the transmembrane and cytoplasmic domains of pneumococcal penicillin-binding proteins 2x and 2b extends beyond that of simple anchoring devices

(2014) K. H. Berg et al.   MICROBIOLOGY-SGM

Molecular surveillance of the subtle septum: discovering a new mode of peptidoglycan synthesis in streptococci

(2014) Ian T. Cadby et al.   MOLECULAR MICROBIOLOGY

Streptococcus pneumoniae PBP2x mid-cell localization requires the C-terminal PASTA domains and is essential for cell shape maintenance

(2014) Katharina Peters et al.   MOLECULAR MICROBIOLOGY

PhoR autokinase activity is controlled by an intermediate in wall teichoic acid metabolism that is sensed by the intracellular PAS domain during the PhoPR-mediated phosphate limitation response ofBacillus subtilis

(2014) Eric Botella et al.   MOLECULAR MICROBIOLOGY

Different walls for rods and balls: the diversity of peptidoglycan

(2014) Robert D. Turner et al.   MOLECULAR MICROBIOLOGY

Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division ofStreptococcus pneumoniae D39

(2014) Ho-Ching T. Tsui et al.   MOLECULAR MICROBIOLOGY

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

Discovery of β-lactam-resistant variants in diverse pneumococcal populations

(2014) Regine Hakenbeck   Genome Medicine

Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes

(2014) Claire Chewapreecha et al.   PLoS Genetics

Interplay of the Serine/Threonine-Kinase StkP and the Paralogs DivIVA and GpsB in Pneumococcal Cell Elongation and Division

(2014) Aurore Fleurie et al.   PLoS Genetics

Sec-secretion and sortase-mediated anchoring of proteins in Gram-positive bacteria

(2013) Olaf Schneewind et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Current concepts in host–microbe interaction leading to pneumococcal pneumonia

(2013) Joshua Vernatter et al.   CURRENT OPINION IN INFECTIOUS DISEASES

The battle with the host over microbial size

(2013) Jeffrey N Weiser   CURRENT OPINION IN MICROBIOLOGY

From models to pathogens: how much have we learned aboutStreptococcus pneumoniaecell division?

(2013) Orietta Massidda et al.   ENVIRONMENTAL MICROBIOLOGY

Effects of Low PBP2b Levels on Cell Morphology and Peptidoglycan Composition in Streptococcus pneumoniae R6

(2013) K. H. Berg et al.   JOURNAL OF BACTERIOLOGY

Colocalization and interaction between elongasome and divisome during a preparative cell division phase inEscherichia coli

(2013) René van der Ploeg et al.   MOLECULAR MICROBIOLOGY

Requirement of essential Pbp2x and GpsB for septal ring closure inStreptococcus pneumoniae D39

(2013) Adrian D. Land et al.   MOLECULAR MICROBIOLOGY

Target evaluation of the non-coding csRNAs reveals a link of the two-component regulatory system CiaRH to competence control inStreptococcus pneumoniae R6

(2013) Anke Schnorpfeil et al.   MOLECULAR MICROBIOLOGY

How to get (a)round: mechanisms controlling growth and division of coccoid bacteria

(2013) Mariana G. Pinho et al.   NATURE REVIEWS MICROBIOLOGY

The Pneumococcus: Epidemiology, Microbiology, and Pathogenesis

(2013) B. Henriques-Normark et al.   Cold Spring Harbor Perspectives in Medicine

Understanding the pneumococcus: transmission and evolution

(2013) Eric S. Donkor   Frontiers in Cellular and Infection Microbiology

The physiology of bacterial cell division

(2012) Alexander J. F. Egan et al.   Annals of the New York Academy of Sciences

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

Recent advances in pneumococcal peptidoglycan biosynthesis suggest new vaccine and antimicrobial targets

(2012) Lok-To Sham et al.   CURRENT OPINION IN MICROBIOLOGY

Molecular mechanisms of β-lactam resistance inStreptococcus pneumoniae

(2012) Regine Hakenbeck et al.   Future Microbiology

A fine scale phenotype-genotype virulence map of a bacterial pathogen

(2012) T. van Opijnen et al.   GENOME RESEARCH

Increased Chain Length Promotes Pneumococcal Adherence and Colonization

(2012) Jesse L. Rodriguez et al.   INFECTION AND IMMUNITY

ZipA Is Required for FtsZ-Dependent Preseptal Peptidoglycan Synthesis prior to Invagination during Cell Division

(2012) L.-P. Potluri et al.   JOURNAL OF BACTERIOLOGY

LytA, Major Autolysin ofStreptococcus pneumoniae, Requires Access to Nascent Peptidoglycan

(2012) Peter Mellroth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae

(2012) Alice Eberhardt et al.   Microbial Drug Resistance

Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk inStreptococcus pneumoniaeD39 cells

(2012) Kyle J. Wayne et al.   MOLECULAR MICROBIOLOGY

Isolation and analysis of cell wall components from Streptococcus pneumoniae

(2011) Nhat Khai Bui et al.   ANALYTICAL BIOCHEMISTRY

Minimization of Bacterial Size Allows for Complement Evasion and Is Overcome by the Agglutinating Effect of Antibody

(2011) Ankur B. Dalia et al.   Cell Host & Microbe

The Requirement for Pneumococcal MreC and MreD Is Relieved by Inactivation of the Gene Encoding PBP1a

(2011) A. D. Land et al.   JOURNAL OF BACTERIOLOGY

Characterization of Mutants Deficient in the L,D-Carboxypeptidase (DacB) and WalRK (VicRK) Regulon, Involved in Peptidoglycan Maturation of Streptococcus pneumoniae Serotype 2 Strain D39

(2011) S. M. Barendt et al.   JOURNAL OF BACTERIOLOGY

Activity of the Two-Component Regulatory System CiaRH in Streptococcus pneumoniae R6

(2011) Alexander Halfmann et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Super-resolution microscopy reveals cell wall dynamics and peptidoglycan architecture in ovococcal bacteria

(2011) Richard Wheeler et al.   MOLECULAR MICROBIOLOGY

Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsXSpn cell division protein in Streptococcus pneumoniae D39

(2011) L.-T. Sham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases

(2010) Catherine Paradis-Bleau et al.   CELL

Localization and Cellular Amounts of the WalRKJ (VicRKX) Two-Component Regulatory System Proteins in Serotype 2 Streptococcus pneumoniae

(2010) K. J. Wayne et al.   JOURNAL OF BACTERIOLOGY

Kinetic Characterization of the WalRKSpn (VicRK) Two-Component System of Streptococcus pneumoniae: Dependence of WalKSpn (VicK) Phosphatase Activity on Its PAS Domain

(2010) A. D. Gutu et al.   JOURNAL OF BACTERIOLOGY

Pneumococcal CbpD is a murein hydrolase that requires a dual cell envelope binding specificity to kill target cells during fratricide

(2010) Vegard Eldholm et al.   MOLECULAR MICROBIOLOGY

Insights into pneumococcal fratricide from the crystal structures of the modular killing factor LytC

(2010) Inmaculada Pérez-Dorado et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Influences of Capsule on Cell Shape and Chain Formation of Wild-Type and pcsB Mutants of Serotype 2 Streptococcus pneumoniae

(2009) S. M. Barendt et al.   JOURNAL OF BACTERIOLOGY

Identification and Characterization of Noncoding Small RNAs in Streptococcus pneumoniae Serotype 2 Strain D39

(2009) H.-C. T. Tsui et al.   JOURNAL OF BACTERIOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

RodZ (YfgA) is required for proper assembly of the MreB actin cytoskeleton and cell shape in E. coli

(2008) Felipe O Bendezú et al.   EMBO JOURNAL

Essentiality, Bypass, and Targeting of the YycFG (VicRK) Two-Component Regulatory System in Gram-Positive Bacteria

(2008) M. E. Winkler et al.   JOURNAL OF BACTERIOLOGY

A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway

(2008) Sarah Dubrac et al.   MOLECULAR MICROBIOLOGY

DOOR: a database for prokaryotic operons

(2008) Fenglou Mao et al.   NUCLEIC ACIDS RESEARCH