Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk inStreptococcus pneumoniaeD39 cells

Recent advances in pneumococcal peptidoglycan biosynthesis suggest new vaccine and antimicrobial targets

(2012) Lok-To Sham et al.   CURRENT OPINION IN MICROBIOLOGY

Regulation of Bacteriocin Production and Cell Death by the VicRK Signaling System in Streptococcus mutans

(2012) D. B. Senadheera et al.   JOURNAL OF BACTERIOLOGY

Purification and Activity Testing of the Full-Length YycFGHI Proteins of Staphylococcus aureus

(2012) Michael Türck et al.   PLoS One

walKandclpPMutations Confer Reduced Vancomycin Susceptibility inStaphylococcus aureus

(2011) Mitsutaka Shoji et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

More than just lysins: peptidoglycan hydrolases tailor the cell wall

(2011) Tsuyoshi Uehara et al.   CURRENT OPINION IN MICROBIOLOGY

The Major Autolysin of Streptococcus gordonii Is Subject to Complex Regulation and Modulates Stress Tolerance, Biofilm Formation, and Extracellular-DNA Release

(2011) Y. Liu et al.   JOURNAL OF BACTERIOLOGY

Characterization of Mutants Deficient in the L,D-Carboxypeptidase (DacB) and WalRK (VicRK) Regulon, Involved in Peptidoglycan Maturation of Streptococcus pneumoniae Serotype 2 Strain D39

(2011) S. M. Barendt et al.   JOURNAL OF BACTERIOLOGY

Cell envelope gene expression in phosphate-limited Bacillus subtilis cells

(2011) E. Botella et al.   MICROBIOLOGY-SGM

The rod to L-form transition of Bacillus subtilis is limited by a requirement for the protoplast to escape from the cell wall sacculus

(2011) Patricia Domínguez-Cuevas et al.   MOLECULAR MICROBIOLOGY

Negative control in two-component signal transduction by transmitter phosphatase activity

(2011) TuAnh Ngoc Huynh et al.   MOLECULAR MICROBIOLOGY

Peptidoglycan Crosslinking Relaxation Plays an Important Role in Staphylococcus aureus WalKR-Dependent Cell Viability

(2011) Aurelia Delaune et al.   PLoS One

Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsXSpn cell division protein in Streptococcus pneumoniae D39

(2011) L.-T. Sham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring

(2011) D. C. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR

(2011) Benjamin P. Howden et al.   PLoS Pathogens

Ligand-Binding PAS Domains in a Genomic, Cellular, and Structural Context

(2010) Jonathan T. Henry et al.   Annual Review of Microbiology

X-Ray Crystal Structure of the DNA-Binding Domain of Response Regulator WalR Essential to the Cell Viability of Staphylococcus aureus and Interaction with Target DNA

(2010) Akihiro DOI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Two-component signaling circuit structure and properties

(2010) Mark Goulian   CURRENT OPINION IN MICROBIOLOGY

Molecular strategies for phosphorylation-mediated regulation of response regulator activity

(2010) Rong Gao et al.   CURRENT OPINION IN MICROBIOLOGY

How important is the phosphatase activity of sensor kinases?

(2010) Linda J Kenney   CURRENT OPINION IN MICROBIOLOGY

Receiver domain structure and function in response regulator proteins

(2010) Robert B Bourret   CURRENT OPINION IN MICROBIOLOGY

Downregulation of GbpB, a Component of the VicRK Regulon, Affects Biofilm Formation and Cell Surface Characteristics ofStreptococcus mutans

(2010) Cristiane Duque et al.   INFECTION AND IMMUNITY

The Putative Hydrolase YycJ (WalJ) Affects the Coordination of Cell Division with DNA Replication in Bacillus subtilis and May Play a Conserved Role in Cell Wall Metabolism

(2010) S. J. Biller et al.   JOURNAL OF BACTERIOLOGY

Localization and Cellular Amounts of the WalRKJ (VicRKX) Two-Component Regulatory System Proteins in Serotype 2 Streptococcus pneumoniae

(2010) K. J. Wayne et al.   JOURNAL OF BACTERIOLOGY

Instability of ackA (Acetate Kinase) Mutations and Their Effects on Acetyl Phosphate and ATP Amounts in Streptococcus pneumoniae D39

(2010) S. Ramos-Montanez et al.   JOURNAL OF BACTERIOLOGY

Kinetic Characterization of the WalRKSpn (VicRK) Two-Component System of Streptococcus pneumoniae: Dependence of WalKSpn (VicK) Phosphatase Activity on Its PAS Domain

(2010) A. D. Gutu et al.   JOURNAL OF BACTERIOLOGY

Regulation of Response Regulator Autophosphorylation through Interdomain Contacts

(2010) Christopher M. Barbieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for the essential YycG sensor histidine kinase in sensing cell division

(2010) Tatsuya Fukushima et al.   MOLECULAR MICROBIOLOGY

Peptidoglycan metabolism is controlled by the WalRK (YycFG) and PhoPR two-component systems in phosphate-limitedBacillus subtiliscells

(2010) Paola Bisicchia et al.   MOLECULAR MICROBIOLOGY

Conserved mechanism for sensor phosphatase control of two-component signaling revealed in the nitrate sensor NarX

(2010) T. N. Huynh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways

(2010) Emily J. Capra et al.   PLoS Genetics

Biological Insights from Structures of Two-Component Proteins

(2009) Rong Gao et al.   Annual Review of Microbiology

Influences of Capsule on Cell Shape and Chain Formation of Wild-Type and pcsB Mutants of Serotype 2 Streptococcus pneumoniae

(2009) S. M. Barendt et al.   JOURNAL OF BACTERIOLOGY

Roles ofrelSpnin stringent response, global regulation and virulence of serotype 2Streptococcus pneumoniaeD39

(2009) Krystyna M. Kazmierczak et al.   MOLECULAR MICROBIOLOGY

Universally applicable methods for monitoring response regulator aspartate phosphorylation both in vitro and in vivo using Phos-tag-based reagents

(2008) Christopher M. Barbieri et al.   ANALYTICAL BIOCHEMISTRY

Response regulator YycF essential for bacterial growth: X-ray crystal structure of the DNA-binding domain and its PhoB-like DNA recognition motif

(2008) Toshihide Okajima et al.   FEBS LETTERS

Essentiality, Bypass, and Targeting of the YycFG (VicRK) Two-Component Regulatory System in Gram-Positive Bacteria

(2008) M. E. Winkler et al.   JOURNAL OF BACTERIOLOGY

A sensor histidine kinase co-ordinates cell wall architecture with cell division inBacillus subtilis

(2008) Tatsuya Fukushima et al.   MOLECULAR MICROBIOLOGY

A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway

(2008) Sarah Dubrac et al.   MOLECULAR MICROBIOLOGY

An essential sensor histidine kinase controlled by transmembrane helix interactions with its auxiliary proteins

(2008) H. Szurmant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA