Molecular mechanisms of β-lactam resistance inStreptococcus pneumoniae

Decrease in Penicillin Susceptibility Due to Heat Shock Protein ClpL in Streptococcus pneumoniae

(2011) Thao Dang-Hien Tran et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of the Two-Component Regulatory System CiaRH in Streptococcus pneumoniae R6

(2011) Alexander Halfmann et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Effect of new alleles of the histidine kinase gene ciaH on the activity of the response regulator CiaR in Streptococcus pneumoniae R6

(2011) M. Muller et al.   MICROBIOLOGY-SGM

Rapid Pneumococcal Evolution in Response to Clinical Interventions

(2011) N. J. Croucher et al.   SCIENCE

Compensatory Evolution of pbp Mutations Restores the Fitness Cost Imposed by β-Lactam Resistance in Streptococcus pneumoniae

(2011) Andrea G. Albarracín Orio et al.   PLoS Pathogens

Bridging cell wall biosynthesis and bacterial morphogenesis

(2010) Pierre-Jean Matteï et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP fromStreptococcus pneumoniae

(2010) Beatriz Maestro et al.   FEBS LETTERS

The pneumococcal eukaryotic-type serine/threonine protein kinase StkP co-localizes with the cell division apparatus and interacts with FtsZ in vitro

(2010) C. Giefing et al.   MICROBIOLOGY-SGM

The Genome of Streptococcus mitis B6 - What Is a Commensal?

(2010) Dalia Denapaite et al.   PLoS One

The highly conserved serine threonine kinase StkP of Streptococcus pneumoniae contributes to penicillin susceptibility independently from genes encoding penicillin-binding proteins

(2009) Ricardo Dias et al.   BMC MICROBIOLOGY

Discovery of New Inhibitors of ResistantStreptococcus pneumoniaePenicillin Binding Protein (PBP) 2x by Structure-Based Virtual Screening

(2009) Laurence Miguet et al.   JOURNAL OF MEDICINAL CHEMISTRY

PBP Active Site Flexibility as the Key Mechanism for β-Lactam Resistance in Pneumococci

(2009) Carlos Contreras-Martel et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparative Genome Analysis of High-Level Penicillin Resistance in Streptococcus pneumoniae

(2009) Amelia G. Tait-Kamradt et al.   Microbial Drug Resistance

Antimicrobial Resistance among Isolates Causing Invasive Pneumococcal Disease before and after Licensure of Heptavalent Conjugate Pneumococcal Vaccine

(2009) Tom Theodore Karnezis et al.   PLoS One

An Important Site in PBP2x of Penicillin-Resistant Clinical Isolates of Streptococcus pneumoniae: Mutational Analysis of Thr338

(2008) I. Zerfass et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Positive selection in penicillin-binding proteins 1a, 2b, and 2x from Streptococcus pneumoniae and its correlation with amoxicillin resistance development

(2008) Michael J. Stanhope et al.   INFECTION GENETICS AND EVOLUTION

A New Model of Pneumococcal Lipoteichoic Acid Structure Resolves Biochemical, Biosynthetic, and Serologic Inconsistencies of the Current Model

(2008) H. S. Seo et al.   JOURNAL OF BACTERIOLOGY

Kinetic Characterization of Lipid II-Ala:Alanyl-tRNA Ligase (MurN) fromStreptococcus pneumoniaeusing Semisynthetic Aminoacyl-lipid II Substrates

(2008) Gianfranco De Pascale et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Penicillin-binding Protein 2x of Streptococcus pneumoniae: Three New Mutational Pathways for Remodelling an Essential Enzyme into a Resistance Determinant

(2008) Patrick Maurer et al.   JOURNAL OF MOLECULAR BIOLOGY