Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2

Cpmer: A new conserved eEF1A2-binding partner that regulates Eomes translation and cardiomyocyte differentiation

(2022) Yao Lyu et al.   Stem Cell Reports

Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment

(2022) Zoe Wefers et al.   Cells

Overexpressing eukaryotic elongation factor 1 alpha (eEF1A) proteins to promote corticospinal axon repair after injury

(2022) Daniel Romaus-Sanjurjo et al.   Cell Death Discovery

mRNA transport, translation, and decay in adult mammalian central nervous system axons

(2022) Jane Jung et al.   NEURON

Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons

(2021) Julio D Perez et al.   eLife

The elongation factor eEF1A2 controls translation and actin dynamics in dendritic spines

(2021) Mònica B. Mendoza et al.   Science Signaling

The translatome of neuronal cell bodies, dendrites, and axons

(2021) Caspar Glock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recapitulation of the EEF1A2 D252H neurodevelopmental disorder-causing missense mutation in mice reveals a toxic gain of function

(2020) Faith C J Davies et al.   HUMAN MOLECULAR GENETICS

Damaging de novo missense variants in EEF1A2 lead to a developmental and degenerative epileptic-dyskinetic encephalopathy

(2020) Gemma L. Carvill et al.   HUMAN MUTATION

Axonal mRNA translation in neurological disorders

(2020) Julie Qiaojin Lin et al.   RNA Biology

Local translation in neurons: visualization and function

(2019) Christine E. Holt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS

(2018) Jik Nijssen et al.   Stem Cell Reports

Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death

(2017) Siqi Cao et al.   HUMAN MOLECULAR GENETICS

Regulation of mRNA Translation in Neurons—A Matter of Life and Death

(2017) Mridu Kapur et al.   NEURON

Biallelic mutations in the gene encoding eEF1A2 cause seizures and sudden death in F0 mice

(2017) Faith C. J. Davies et al.   Scientific Reports

Dynamic Axonal Translation in Developing and Mature Visual Circuits

(2016) Toshiaki Shigeoka et al.   CELL

Novel de novoEEF1A2missense mutations causing epilepsy and intellectual disability

(2016) Wayne W.K. Lam et al.   Molecular Genetics & Genomic Medicine

De novo EEF1A2mutations in patients with characteristic facial features, intellectual disability, autistic behaviors and epilepsy

(2014) J. Nakajima et al.   CLINICAL GENETICS

Mammalian translation elongation factor eEF1A2: X-ray structure and new features of GDP/GTP exchange mechanism in higher eukaryotes

(2014) Thibaut Crepin et al.   NUCLEIC ACIDS RESEARCH

Degradation of Newly Synthesized Polypeptides by Ribosome-Associated RACK1/c-Jun N-Terminal Kinase/Eukaryotic Elongation Factor 1A2 Complex

(2013) V. Gandin et al.   MOLECULAR AND CELLULAR BIOLOGY

The Local Transcriptome in the Synaptic Neuropil Revealed by Deep Sequencing and High-Resolution Imaging

(2012) Iván J. Cajigas et al.   NEURON

Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

(2012) Àlex Bayés et al.   PLoS One

A mouse model of the fragile X premutation: Effects on behavior, dendrite morphology, and regional rates of cerebral protein synthesis

(2011) Mei Qin et al.   NEUROBIOLOGY OF DISEASE

Characterization of the proteome, diseases and evolution of the human postsynaptic density

(2010) Àlex Bayés et al.   NATURE NEUROSCIENCE

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

(2010) L. F. Gumy et al.   RNA

Axonal mRNA in Uninjured and Regenerating Cortical Mammalian Axons

(2009) A. M. Taylor et al.   JOURNAL OF NEUROSCIENCE

Structural Models of Human eEF1A1 and eEF1A2 Reveal Two Distinct Surface Clusters of Sequence Variation and Potential Differences in Phosphorylation

(2009) Dinesh C. Soares et al.   PLoS One