Overexpressing eukaryotic elongation factor 1 alpha (eEF1A) proteins to promote corticospinal axon repair after injury

A Critical Role for DLK and LZK in Axonal Repair in the Mammalian Spinal Cord

(2022) Junmi M. Saikia et al.   JOURNAL OF NEUROSCIENCE

eEF1A2 knockdown impairs neuronal proliferation and inhibits neurite outgrowth of differentiating neurons

(2022) Kanitin Rumpansuwon et al.   NEUROREPORT

The elongation factor eEF1A2 controls translation and actin dynamics in dendritic spines

(2021) Mònica B. Mendoza et al.   Science Signaling

Identification of therapeutics that target eEF1A2 and upregulate utrophin A translation in dystrophic muscles

(2020) Christine Péladeau et al.   Nature Communications

EEF1A1 deacetylation enables transcriptional activation of remyelination

(2020) Mert Duman et al.   Nature Communications

Actin dynamics in the growth cone: a key player in axon regeneration

(2020) Sérgio Carvalho Leite et al.   CURRENT OPINION IN NEUROBIOLOGY

AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration

(2019) Haoliang Huang et al.   Cell Death & Disease

Phosphoinositide Phosphatases in Cancer Cell Dynamics—Beyond PI3K and PTEN

(2019) Takeshi Ijuin   SEMINARS IN CANCER BIOLOGY

Tau drives translational selectivity by interacting with ribosomal proteins

(2019) Shon A. Koren et al.   ACTA NEUROPATHOLOGICA

Translation Elongation and Recoding in Eukaryotes

(2018) Thomas E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS

(2018) Meifan Chen et al.   Cell Reports

Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury

(2018) Jessica M. Meves et al.   EXPERIMENTAL NEUROLOGY

Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival

(2018) Alejandro Losada et al.   BRITISH JOURNAL OF CANCER

The role of translation elongation factor eEF1 subunits in neurodevelopmental disorders

(2018) Fiona McLachlan et al.   HUMAN MUTATION

Intrinsic Control of Axon Regeneration

(2016) Zhigang He et al.   NEURON

New insights on the interaction between the isoforms 1 and 2 of human translation elongation factor 1A

(2015) Nunzia Migliaccio et al.   BIOCHIMIE

Truncation of the A,A∗,A′ helices segment impairs the actin bundling activity of mammalian eEF1A1

(2015) Dmytro O. Vlasenko et al.   FEBS LETTERS

Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice

(2015) C. G. Geoffroy et al.   JOURNAL OF NEUROSCIENCE

Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms

(2015) Homaira Nawabi et al.   NEURON

Injury-Induced Decline of Intrinsic Regenerative Ability Revealed by Quantitative Proteomics

(2015) Stephane Belin et al.   NEURON

Restoration of skilled locomotion by sprouting corticospinal axons induced by co-deletion of PTEN and SOCS3

(2015) Duo Jin et al.   Nature Communications

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration

(2014) Liu Yang et al.   Nature Communications

EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma

(2013) Rossella Pellegrino et al.   HEPATOLOGY

Traumatic injury induces changes in the expression of the serotonin 1A receptor in the spinal cord of lampreys

(2013) María Eugenia Cornide-Petronio et al.   NEUROPHARMACOLOGY

Translation elongation factor-1A1 (eEF1A1) localizes to the spine by domain III

(2012) Sun-Jung Cho et al.   BMB Reports

The functions and regulation of the PTEN tumour suppressor

(2012) Min Sup Song et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kruppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

(2012) M. G. Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Assessing Spinal Axon Regeneration and Sprouting in Nogo-, MAG-, and OMgp-Deficient Mice

(2010) Jae K. Lee et al.   NEURON

Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis

(2010) T M Leclercq et al.   ONCOGENE

Eef1a2 Promotes Cell Growth, Inhibits Apoptosis and Activates JAK/STAT and AKT Signaling in Mouse Plasmacytomas

(2010) Zhaoyang Li et al.   PLoS One

The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance

(2010) E. W. Dent et al.   Cold Spring Harbor Perspectives in Biology

eEF1A2 and neuronal degeneration

(2009) Catherine M. Abbott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Eukaryotic Elongation Factor 1A2 Cooperates with Phosphatidylinositol-4 Kinase III   To Stimulate Production of Filopodia through Increased Phosphatidylinositol-4,5 Bisphosphate Generation

(2008) S. Jeganathan et al.   MOLECULAR AND CELLULAR BIOLOGY

PTEN signaling in brain: neuropathology and tumorigenesis

(2008) R Endersby et al.   ONCOGENE

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE

A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules

(2007) Ganna Panasyuk et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY