Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9

Whole organism profiling of the Timp gene family

(2023) David Peeney et al.   Matrix Biology Plus

Neutrophils in chronic inflammatory diseases

(2022) Andrea Herrero-Cervera et al.   Cellular & Molecular Immunology

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancer

(2022) David Peeney et al.   CARCINOGENESIS

Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology

(2022) Luiz G.N. de Almeida et al.   PHARMACOLOGICAL REVIEWS

Deglycosylation Increases the Aggregation and Angiogenic Properties of Mutant Tissue Inhibitor of Metalloproteinase 3 Protein: Implications for Sorsby Fundus Dystrophy

(2022) Jian Hua Qi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Structural characterisation of inhibitory and non-inhibitory MMP-9–TIMP-1 complexes and implications for regulatory mechanisms of MMP-9

(2021) Łukasz Charzewski et al.   Scientific Reports

Establishment of Structure-Function Relationship of Tissue Inhibitor of Metalloproteinase-1 for Its Interaction with CD63: Implication for Cancer Therapy

(2020) Richard B. Warner et al.   Scientific Reports

Preparation of a phosphotyrosine-protein standard for use in semiquantitative western blotting with enhanced chemiluminescence

(2020) Nancy Kendrick et al.   PLoS One

The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases

(2020) Griselda A Cabral-Pacheco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition

(2019) Maryam Raeeszadeh-Sarmazdeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis

(2019) Alexander J. Baker-Williams et al.   Cell Reports

TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer

(2019) David Peeney et al.   CARCINOGENESIS

Matrisome-Associated Gene Expression Patterns Correlating with TIMP2 in Cancer

(2019) David Peeney et al.   Scientific Reports

Recognizing the Molecular Multifunctionality and Interactome of TIMP-1

(2018) Barbara Grünwald et al.   TRENDS IN CELL BIOLOGY

Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1

(2015) Jennifer Vandooren et al.   BIOCHEMICAL JOURNAL

The role of TIMPs in regulation of extracellular matrix proteolysis

(2015) Valerie Arpino et al.   MATRIX BIOLOGY

A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders

(2015) Sarah M. Reinhard et al.   Frontiers in Cellular Neuroscience

Matrix metalloproteinases in inflammation

(2014) Liisa Nissinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Basis for substrate recognition and distinction by matrix metalloproteinases

(2014) Boris I. Ratnikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade

(2013) Jennifer Vandooren et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

(2013) Jyotica Batra et al.   PLoS One

Matrix metalloproteinase inhibition therapy for vascular diseases

(2012) Andrew C. Newby   VASCULAR PHARMACOLOGY

A therapeutic role for matrix metalloproteinase inhibitors in lung diseases?

(2011) R. E. Vandenbroucke et al.   EUROPEAN RESPIRATORY JOURNAL

Mechanism of Heparin Acceleration of Tissue Inhibitor of Metalloproteases-1 (TIMP-1) Degradation by the Human Neutrophil Elastase

(2011) Gabriel L. C. Nunes et al.   PLoS One

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Biological role of matrix metalloproteinases: a critical balance

(2010) S. Loffek et al.   EUROPEAN RESPIRATORY JOURNAL

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

(2010) Dimitra Bourboulia et al.   SEMINARS IN CANCER BIOLOGY

Neutrophil MMP-9 Proenzyme, Unencumbered by TIMP-1, Undergoes Efficient Activationin Vivoand Catalytically Induces Angiogenesis via a Basic Fibroblast Growth Factor (FGF-2)/FGFR-2 Pathway

(2009) Veronica C. Ardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY