Whole organism profiling of the Timp gene family

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancer

(2022) David Peeney et al.   CARCINOGENESIS

Cross-tissue organization of the fibroblast lineage

(2021) Matthew B. Buechler et al.   NATURE

Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles

(2021) Emily J. Ross et al.   Scientific Reports

Regulation of ADAMTS Proteases

(2021) Keron W. J. Rose et al.   Frontiers in Molecular Biosciences

Establishment of Structure-Function Relationship of Tissue Inhibitor of Metalloproteinase-1 for Its Interaction with CD63: Implication for Cancer Therapy

(2020) Richard B. Warner et al.   Scientific Reports

Single-cell analysis reveals fibroblast clusters linked to immunotherapy resistance in cancer

(2020) Yann Kieffer et al.   Cancer Discovery

Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology

(2020) Dong Fan et al.   Frontiers in Physiology

A Quantitative Proteome Map of the Human Body

(2020) Lihua Jiang et al.   CELL

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Functional disparities within the TIMP family in cancer: hints from molecular divergence

(2019) Celina Eckfeld et al.   CANCER AND METASTASIS REVIEWS

The human secretome

(2019) Mathias Uhlén et al.   Science Signaling

Matrisome-Associated Gene Expression Patterns Correlating with TIMP2 in Cancer

(2019) David Peeney et al.   Scientific Reports

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

(2018) Fumitaka Mizoguchi et al.   Nature Communications

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

(2018) Ting Xie et al.   Cell Reports

Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease

(2018) Swati Naphade et al.   Frontiers in Neuroscience

Recognizing the Molecular Multifunctionality and Interactome of TIMP-1

(2018) Barbara Grünwald et al.   TRENDS IN CELL BIOLOGY

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

TIMP3 is Regulated by Pericytes upon Shear Stress Detection Leading to a Modified Endothelial Cell Response

(2017) C. Schrimpf et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Context-Dependent Development of Lymphoid Stroma from Adult CD34+ Adventitial Progenitors

(2016) Katarzyna M. Sitnik et al.   Cell Reports

TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice

(2015) J. Kobuch et al.   HAEMATOLOGICA

Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator–Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate–Salt HypertensionNovelty and Significance

(2015) Pimonrat Ketsawatsomkron et al.   HYPERTENSION

The role of TIMPs in regulation of extracellular matrix proteolysis

(2015) Valerie Arpino et al.   MATRIX BIOLOGY

TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice

(2015) J. Kobuch et al.   HAEMATOLOGICA

Mesothelial cells in tissue repair and fibrosis

(2015) Steven E. Mutsaers et al.   Frontiers in Pharmacology

Cytokine functions of TIMP-1

(2013) Christian Ries   CELLULAR AND MOLECULAR LIFE SCIENCES

An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells

(2013) H Han et al.   ONCOGENE

Role of shear stress and stretch in vascular mechanobiology

(2011) D. Lu et al.   Journal of the Royal Society Interface

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

(2010) Dimitra Bourboulia et al.   SEMINARS IN CANCER BIOLOGY

TIMPs and cardiac remodeling: ‘Embracing the MMP-independent-side of the family’

(2009) Davy Vanhoutte et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Loss of TIMP3 Enhances Interstitial Nephritis and Fibrosis

(2009) Z. Kassiri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tissue Inhibitors of Metalloproteinases in Cell Signaling: Metalloproteinase-Independent Biological Activities

(2008) W. G. Stetler-Stevenson   Science Signaling

Endogenous Fibroblastic Progenitor Cells in the Adult Mouse Lung Are Highly Enriched in the Sca-1 Positive Cell Fraction

(2008) Jonathan L. McQualter et al.   STEM CELLS