Dickkopf-1 and ROCK2 upregulation and associated protein aggregation in pseudoexfoliation syndrome and glaucoma

Full title: The canonical Wnt signaling pathway inhibits the glucocorticoid receptor signaling pathway in the trabecular meshwork

(2021) Chenna Kesavulu Sugali et al.   AMERICAN JOURNAL OF PATHOLOGY

Perspectives on ROCK2 as a Therapeutic Target for Alzheimer’s Disease

(2021) Audrey J. Weber et al.   Frontiers in Cellular Neuroscience

Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma

(2020) Bushra Hayat et al.   JOURNAL OF HUMAN GENETICS

Beta-Catenin in Pseudoexfoliation Syndrome

(2020) Joanna Stafiej et al.   Applied Sciences-Basel

Dickkopf-related protein-1 inhibition attenuates amyloid-beta pathology associated to Alzheimer's disease

(2020) Romain Menet et al.   NEUROCHEMISTRY INTERNATIONAL

Altered unfolded protein response and proteasome impairment in pseudoexfoliation pathogenesis

(2019) Bushra Hayat et al.   EXPERIMENTAL EYE RESEARCH

De novo variants in an extracellular matrix protein coding gene, fibulin-5 (FBLN5) are associated with pseudoexfoliation

(2019) Biswajit Padhy et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Evaluation of Tear Fluid and Aqueous Humor Concentration of Clusterin as Biomarkers for Early Diagnosis of Pseudoexfoliation Syndrome and Pseudoexfoliative Glaucoma

(2019) Birsen Can Demirdöğen et al.   CURRENT EYE RESEARCH

DKK1 promotes hepatocellular carcinoma inflammation, migration and invasion: Implication of TGF-β1

(2019) Maha Fezza et al.   PLoS One

Evaluation of tear and aqueous humor level, and genetic variants of connective tissue growth factor as biomarkers for early detection of pseudoexfoliation syndrome/glaucoma

(2019) Birsen Can Demirdöğen et al.   EXPERIMENTAL EYE RESEARCH

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil

(2018) Katherine J. Sellers et al.   Alzheimers & Dementia

Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways

(2017) Andreas Schmid et al.   FEBS LETTERS

Pseudoexfoliation and Alzheimer’s associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression

(2017) Biswajit Padhy et al.   HUMAN MOLECULAR GENETICS

The regulation of β-catenin activity and function in cancer: therapeutic opportunities

(2017) Shuang Shang et al.   Oncotarget

Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer

(2015) Óscar Aguilera et al.   Oncotarget

The Rho-kinase inhibitor HA-1077 suppresses proliferation/migration and induces apoptosis of urothelial cancer cells

(2014) Hideyuki Abe et al.   BMC CANCER

Role of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

(2014) Biswajit Padhy et al.   EXPERIMENTAL EYE RESEARCH

Plasma and vitreous fluid levels of Dickkopf-1 in patients with diabetic retinopathy

(2014) F Qiu et al.   EYE

Dissecting the roles of ROCK isoforms in stress-induced cell detachment

(2013) Jianjian Shi et al.   CELL CYCLE

Is There Any Relation Between Pseudoexfoliation Syndrome and Alzheimer’s Type Dementia?

(2013) Tongabay Cumurcu et al.   Seminars in Ophthalmology

Cellular mechanisms of protein aggregate propagation

(2012) Brandon B. Holmes et al.   CURRENT OPINION IN NEUROLOGY

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

(2012) R Killick et al.   MOLECULAR PSYCHIATRY

Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-OHDA-lesioned rats

(2012) Yaoyan Dun et al.   NEUROSCIENCE LETTERS

Continuous Antagonism by Dkk1 Counter Activates Canonical Wnt Signaling and Promotes Cardiomyocyte Differentiation of Embryonic Stem Cells

(2011) Meena Rai et al.   STEM CELLS AND DEVELOPMENT

Assessment of Circulating Dickkopf-1 with a New Two-Site Immunoassay in Healthy Subjects and Women with Breast Cancer and Bone Metastases

(2009) Nathalie Voorzanger-Rousselot et al.   CALCIFIED TISSUE INTERNATIONAL

Inhibition of Rho Kinases Enhances the Degradation of Mutant Huntingtin

(2009) Peter O. Bauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease

(2009) Maria Cristina Rosi et al.   JOURNAL OF NEUROCHEMISTRY

Altered expression of CD44 and DKK1 in the progression of Barrett’s esophagus to esophageal adenocarcinoma

(2009) T. Darlavoix et al.   VIRCHOWS ARCHIV

Wnt4 inhibits β-catenin/TCF signalling by redirecting β-catenin to the cell membrane

(2008) Pascal Bernard et al.   BIOLOGY OF THE CELL

The role of Dickkopf-1 in bone development, homeostasis, and disease

(2008) J. J. Pinzone et al.   BLOOD

Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma

(2008) Martin Kaiser et al.   EUROPEAN JOURNAL OF HAEMATOLOGY