N-retinylidene-N-retinylethanolamine degradation in human retinal pigment epithelial cells via memantine- and ifenprodil-mediated autophagy

Transcriptome Analysis of Long-Term Exposure to Blue Light in Retinal Pigment Epithelial Cells

(2022) Hong Lan Jin et al.   Biomolecules & Therapeutics

Computational Modeling of Therapy with the NMDA Antagonist in Neurodegenerative Disease: Information Theory in the Mechanism of Action of Memantine

(2022) Dariusz Świetlik et al.   International Journal of Environmental Research and Public Health

Protective Effect of Ribes nigrum Extract against Blue Light-Induced Retinal Degeneration In Vitro and In Vivo

(2022) Chae Young Shin et al.   Antioxidants

NMDA receptor antagonists reduce amyloid-β deposition by modulating calpain-1 signaling and autophagy, rescuing cognitive impairment in 5XFAD mice

(2022) Júlia Companys-Alemany et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Photooxidation of A2E by Blue Light Regulates Heme Oxygenase 1 Expression via NF-κB and Lysine Methyltransferase 2A in ARPE-19 Cells

(2022) Chae Young Shin et al.   Life-Basel

Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity

(2021) Elena Bechthold et al.   JOURNAL OF MEDICINAL CHEMISTRY

Solanum melongena L. Extract Protects Retinal Pigment Epithelial Cells from Blue Light-Induced Phototoxicity in In Vitro and In Vivo Models

(2021) Thu Nguyen Minh Pham et al.   Nutrients

Ifenprodil Improves Long-Term Neurologic Deficits Through Antagonizing Glutamate-Induced Excitotoxicity After Experimental Subarachnoid Hemorrhage

(2021) Jing-yi Sun et al.   Translational Stroke Research

Reducing lipofuscin accumulation and cardiomyocytic senescence of aging heart by enhancing autophagy

(2021) Wen-wen Li et al.   EXPERIMENTAL CELL RESEARCH

Molecular regulation of autophagy machinery by mTOR‐dependent and ‐independent pathways

(2020) Md. Abdul Alim Al‐Bari et al.   Annals of the New York Academy of Sciences

Ifenprodil rapidly ameliorates depressive-like behaviors, activates mTOR signaling and modulates proinflammatory cytokines in the hippocampus of CUMS rats

(2020) Yamin Yao et al.   PSYCHOPHARMACOLOGY

Lysosomal Biology and Function: Modern View of Cellular Debris Bin

(2020) Purvi C. Trivedi et al.   Cells

Photoactivation of N-retinylidene-N-retinylethanolamine compromises autophagy in retinal pigmented epithelial cells

(2019) Seo Yeon Jeong et al.   FOOD AND CHEMICAL TOXICOLOGY

Neuroprotective effects of memantine via enhancement of autophagy

(2019) Kazuoki Hirano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chronic minocycline treatment improves hippocampal neuronal structure, NMDA receptor function, and memory processing in Fmr1 knockout mice

(2018) S.Y. Yau et al.   NEUROBIOLOGY OF DISEASE

Exploring the Role of Autophagy-Related Gene 5 (ATG5) Yields Important Insights Into Autophagy in Autoimmune/Autoinflammatory Diseases

(2018) Xin Ye et al.   Frontiers in Immunology

A novel fluorescence-based assay for measuring A2E removal from human retinal pigment epithelial cells to screen for age-related macular degeneration inhibitors

(2016) Hong Lan Jin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates

(2015) Junghyun Lim et al.   PLoS Genetics

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Keap1 degradation by autophagy for the maintenance of redox homeostasis

(2012) K. Taguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex

(2011) Koutaro Ishibashi et al.   Autophagy

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

Neurosteroid modulation of N-methyl-d-aspartate receptors: Molecular mechanism and behavioral effects

(2011) Miloslav Korinek et al.   STEROIDS

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

(2008) S Sarkar et al.   CELL DEATH AND DIFFERENTIATION

Gene-environment interaction in progression of AMD: the CFH gene, smoking and exposure to chronic infection

(2008) P. N. Baird et al.   HUMAN MOLECULAR GENETICS

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL