Reduced miR‐513a‐5p expression in COPD may regulate airway mucous cell hyperplasia through TFR1‐dependent signaling

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules

(2022) Oanh N. Hoang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Computational Modeling of Macrophage Iron Sequestration during Host Defense against Aspergillus

(2022) Bandita Adhikari et al.   mSphere

Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model

(2022) Zhuo Pei et al.   Redox Biology

Molecular mechanisms of ferroptosis and relevance to inflammation

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GOLD COPD report: 2023 update

(2022) Priya Venkatesan   Lancet Respiratory Medicine

Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease

(2021) Sebastian T Lugg et al.   THORAX

Differential Redox State and Iron Regulation in Chronic Obstructive Pulmonary Disease, Acute Respiratory Distress Syndrome and Coronavirus Disease 2019

(2021) Lorena Duca et al.   Antioxidants

Effect of curcumin on lung epithelial injury and ferroptosis induced by cigarette smoke

(2021) Xin Tang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort

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Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma

(2020) Md. Khadem Ali et al.   EUROPEAN RESPIRATORY JOURNAL

Decreased miR-29b expression is associated with airway inflammation in chronic obstructive pulmonary disease

(2019) Kun Tang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

HSP90 inhibitor geldanamycin reverts IL-13– and IL-17–induced airway goblet cell metaplasia

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Mucins, Mucus, and Goblet Cells

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microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach

(2017) Griet Conickx et al.   Scientific Reports

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

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Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

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Differential Expression of MicroRNAs in Chronic Obstructive Pulmonary Disease

(2016) Murat KARA et al.   Advances in Clinical and Experimental Medicine

Biogenesis of cytosolic and nuclear iron–sulfur proteins and their role in genome stability

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Airway IL-1β and Systemic Inflammation as Predictors of Future Exacerbation Risk in Asthma and COPD

(2015) Juan-juan Fu et al.   CHEST

Effects of Iron Chelators on Pulmonary Iron Overload and Oxidative Stress in β-Thalassemic Mice

(2015) Paranee Yatmark et al.   PHARMACOLOGY

A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary disease

(2015) Annabel H Nickol et al.   BMJ Open

MicroRNA clusters: dysregulation in lung adenocarcinoma and COPD

(2014) S. Molina-Pinelo et al.   EUROPEAN RESPIRATORY JOURNAL

Increased Iron Sequestration in Alveolar Macrophages in Chronic Obtructive Pulmonary Disease

(2014) Quentin Philippot et al.   PLoS One

Anemia and iron deficiency in COPD patients: prevalence and the effects of correction of the anemia with erythropoiesis stimulating agents and intravenous iron

(2014) Donald S Silverberg et al.   BMC Pulmonary Medicine

A 3-D airway epithelial cell and macrophage co-culture system to study Rhodococcus equi infection

(2013) Ute Schwab et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Gene expression networks in COPD: microRNA and mRNA regulation

(2011) Michael E Ezzie et al.   THORAX

Integration of Genomic and Genetic Approaches Implicates IREB2 as a COPD Susceptibility Gene

(2009) Dawn L. DeMeo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Particulate Matter in Cigarette Smoke Alters Iron Homeostasis to Produce a Biological Effect

(2008) Andrew J. Ghio et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE