Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma

Role of iron in the pathogenesis of respiratory disease

(2017) Md Khadem Ali et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2

(2017) Richard Y. Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c

(2017) Gang Liu et al.   JOURNAL OF PATHOLOGY

Pulmonary Iron Homeostasis in Hepcidin Knockout Mice

(2017) Jean-Christophe Deschemin et al.   Frontiers in Physiology

Programmed Death Ligand 1 Promotes Early-LifeChlamydiaRespiratory Infection–Induced Severe Allergic Airway Disease

(2016) Malcolm R. Starkey et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA sequencing

(2016) Åsa K Björklund et al.   NATURE IMMUNOLOGY

Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease

(2015) Alan Chen-Yu Hsu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pathophysiology of Iron Homeostasis during Inflammatory States

(2015) Bobby J. Cherayil   JOURNAL OF PEDIATRICS

Maternal pregnancy weight gain and cord blood iron status are associated with eosinophilia in infancy

(2015) R Weigert et al.   Journal of Perinatology

Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization

(2015) M J Gold et al.   Mucosal Immunology

Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma

(2015) Ama-Tawiah Essilfie et al.   THORAX

Iron Status is Associated with Asthma and Lung Function in US Women

(2015) Emily P. Brigham et al.   PLoS One

An exploratory study of the associations between maternal iron status in pregnancy and childhood wheeze and atopy

(2014) Bright I. Nwaru et al.   BRITISH JOURNAL OF NUTRITION

Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis

(2014) Philip M. Hansbro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chlamydia muridarum Infection Subverts Dendritic Cell Function to Promote Th2 Immunity and Airways Hyperreactivity

(2014) G. E. Kaiko et al.   JOURNAL OF IMMUNOLOGY

Zn/Ga−DFO iron–chelating complex attenuates the inflammatory process in a mouse model of asthma

(2014) Haim Bibi et al.   Redox Biology

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

(2013) Emma L. Beckett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

(2013) Adam Collison et al.   NATURE MEDICINE

Exposure to Biomass Smoke Extract Enhances Fibronectin Release from Fibroblasts

(2013) David Krimmer et al.   PLoS One

Regulation of Iron Uptake in Primary Culture Rat Hepatocytes

(2013) Shakil Ahmad et al.   SHOCK

Components of Streptococcus pneumoniae Suppress Allergic Airways Disease and NKT Cells by Inducing Regulatory T Cells

(2012) A. N. Thorburn et al.   JOURNAL OF IMMUNOLOGY

Influence of DMT1 and iron status on inflammatory responses in the lung

(2011) Jonghan Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Iron administration reduces airway hyperreactivity and eosinophilia in a mouse model of allergic asthma

(2011) H. Maazi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interleukin-13 Promotes Susceptibility to Chlamydial Infection of the Respiratory and Genital Tracts

(2011) Kelly L. Asquith et al.   PLoS Pathogens

Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology

(2010) Jay C. Horvat et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chlamydial Respiratory Infection during Allergen Sensitization Drives Neutrophilic Allergic Airways Disease

(2010) J. C. Horvat et al.   JOURNAL OF IMMUNOLOGY

Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease

(2010) A. N. Thorburn et al.   THORAX

Iron and Ferritin Concentrations in Exhaled Breath Condensate of Children with Asthma

(2009) Ž. Vlašić et al.   JOURNAL OF ASTHMA