Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice

(2015) Simon D. Pouwels et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Emphysema Requires the Receptor for Advanced Glycation End-Products Triggering on Structural Cells

(2015) Koichi Waseda et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cigarette Smoke–Induced Damage-Associated Molecular Pattern Release from Necrotic Neutrophils Triggers Proinflammatory Mediator Release

(2015) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients

(2015) S. D. Pouwels et al.   EUROPEAN RESPIRATORY JOURNAL

Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains

(2015) Maciej Cabanski et al.   INFLAMMATION RESEARCH

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

The Receptor for Advanced Glycation End Products (RAGE) Contributes to the Progression of Emphysema in Mice

(2015) Nisha Sambamurthy et al.   PLoS One

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

(2014) Kenji Mizumura et al.   JOURNAL OF CLINICAL INVESTIGATION

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent

(2014) E. Doz et al.   JOURNAL OF IMMUNOLOGY

Conditional Overexpression of Receptors for Advanced Glycation End-Products in the Adult Murine Lung Causes Airspace Enlargement and Induces Inflammation

(2013) Megan P. Stogsdill et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A specific DAMP profile identifies susceptibility to smoke-induced airway inflammation

(2013) S. D. Pouwels et al.   EUROPEAN RESPIRATORY JOURNAL

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

DAMPs activating innate and adaptive immune responses in COPD

(2013) S D Pouwels et al.   Mucosal Immunology

RAGE signaling by alveolar macrophages influences tobacco smoke-induced inflammation

(2012) Adam B. Robinson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema

(2012) Chang Hyeok An et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease

(2012) Simona E. Budulac et al.   PLoS One

Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function

(2011) María Soler Artigas et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke

(2011) Beata Kosmider et al.   PLoS One

Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End Products in Chronic Obstructive Pulmonary Disease

(2010) Nassima Ferhani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Extracellular Adenosine Triphosphate and Chronic Obstructive Pulmonary Disease

(2010) Marek Lommatzsch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Decoding Cell Death Signals in Inflammation and Immunity

(2010) Laurence Zitvogel et al.   CELL

TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure

(2010) Elisabetta Pace et al.   HUMAN IMMUNOLOGY

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A hypothesis for the initiation of COPD

(2009) E. G. Tzortzaki et al.   EUROPEAN RESPIRATORY JOURNAL

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Immunologic Aspects of Chronic Obstructive Pulmonary Disease

(2009) Manuel G. Cosio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of RAGE in Pulmonary Fibrosis

(2008) Markus A. Queisser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Comparison of Cigarette Smoke-Induced Acute Inflammation in Multiple Strains of Mice and the Effect of a Matrix Metalloproteinase Inhibitor on These Responses

(2008) A. Morris et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS