Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Artesunate induces G2/M cell cycle arrest through autophagy induction in breast cancer cells

(2014) Kai Chen et al.   ANTI-CANCER DRUGS

Artesunate induces necrotic cell death in schwannoma cells

(2014) R W Button et al.   Cell Death & Disease

Artesunate inhibits the growth of gastric cancer cells through the mechanism of promoting oncosis both in vitro and in vivo

(2013) Xiang Zhou et al.   ANTI-CANCER DRUGS

Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin

(2013) Xiao-Xue Du et al.   BIOMEDICINE & PHARMACOTHERAPY

Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells

(2013) Yoshinobu Odaka et al.   CARCINOGENESIS

The role of necroptosis, an alternative form of cell death, in cancer therapy

(2013) Xinfang Yu et al.   Expert Review of Anticancer Therapy

Artemisinins: Pharmacological actions beyond anti-malarial

(2013) Wanxing Eugene Ho et al.   PHARMACOLOGY & THERAPEUTICS

Ionizing Radiation Potentiates Dihydroartemisinin-Induced Apoptosis of A549 Cells via a Caspase-8-Dependent Pathway

(2013) Tongsheng Chen et al.   PLoS One

Anti-cancer activity of DHA on gastric cancer—an in vitro and in vivo study

(2013) Haijun Sun et al.   TUMOR BIOLOGY

Evaluating cell lines as tumour models by comparison of genomic profiles

(2013) Silvia Domcke et al.   Nature Communications

A plausible mechanism for the antimalarial activity of artemisinin: A computational approach

(2013) Ashutosh Shandilya et al.   Scientific Reports

Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells

(2012) Zhongyong Jiang et al.   ANTI-CANCER DRUGS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Minireview: Human Ovarian Cancer: Biology, Current Management, and Paths to Personalizing Therapy

(2012) Ignacio Romero et al.   ENDOCRINOLOGY

Dihydroartemisinin Ameliorates Inflammatory Disease by Its Reciprocal Effects on Th and Regulatory T Cell Function via Modulating the Mammalian Target of Rapamycin Pathway

(2012) Yan G. Zhao et al.   JOURNAL OF IMMUNOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Many stimuli pull the necrotic trigger, an overview

(2011) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

Platinum resistance in breast and ovarian cancer cell lines

(2011) Niels Eckstein   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Artesunate Induces Oxidative DNA Damage, Sustained DNA Double-Strand Breaks, and the ATM/ATR Damage Response in Cancer Cells

(2011) N. Berdelle et al.   MOLECULAR CANCER THERAPEUTICS

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

(2010) Amy E. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production

(2010) Anne Hamacher-Brady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Molecular Mechanism of Action of Artemisinin—The Debate Continues

(2010) Paul M. O’Neill et al.   MOLECULES

Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo

(2009) Ji-Hui Du et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pharmacokinetics and Pharmacodynamics of Endoperoxide Antimalarials

(2009) Anirudh Gautam et al.   CURRENT DRUG METABOLISM

Multicellular spheroids in ovarian cancer metastases: Biology and pathology

(2009) Kristy Shield et al.   GYNECOLOGIC ONCOLOGY

Ovarian cancer

(2009) Bryan T Hennessy et al.   LANCET

Artesunate Derived from Traditional Chinese Medicine Induces DNA Damage and Repair

(2008) P. C.H. Li et al.   CANCER RESEARCH

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

(2008) J. Hou et al.   CLINICAL CANCER RESEARCH

Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy

(2008) Tao Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE