OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates

Inositol lipid phosphatases in membrane trafficking and human disease

(2014) Peter G. Billcliff et al.   BIOCHEMICAL JOURNAL

Direct interaction of actin filaments with F-BAR protein pacsin2

(2014) J. Kostan et al.   EMBO REPORTS

Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein–protein interactions

(2014) Georg H. H. Borner et al.   MOLECULAR BIOLOGY OF THE CELL

The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1

(2014) Zenobia B. Mehta et al.   TRAFFIC

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

(2014) Ramiro Nández et al.   eLife

Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting

(2013) Yue Sun et al.   DEVELOPMENTAL CELL

Syndapin - a membrane remodelling and endocytic F-BAR protein

(2013) Annie Quan et al.   FEBS Journal

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis

(2013) Sai Srinivas Panapakkam Giridharan et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Drosophila F-BAR protein Syndapin contributes to coupling the plasma membrane and contractile ring in cytokinesis

(2013) T. Takeda et al.   Open Biology

Distinct and Overlapping Roles for AP-1 and GGAs Revealed by the “Knocksideways” System

(2012) Jennifer Hirst et al.   CURRENT BIOLOGY

The NF-κB Signaling Protein Bcl10 Regulates Actin Dynamics by Controlling AP1 and OCRL-Bearing Vesicles

(2012) Sabrina Marion et al.   DEVELOPMENTAL CELL

The Lowe syndrome protein OCRL1 is involved in primary cilia assembly

(2012) Brian G. Coon et al.   HUMAN MOLECULAR GENETICS

The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module

(2012) Vanessa A. van Rahden et al.   HUMAN MOLECULAR GENETICS

OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome

(2012) Na Luo et al.   HUMAN MOLECULAR GENETICS

The F-BAR Protein PACSIN2 Regulates Epidermal Growth Factor Receptor Internalization

(2012) Bart-Jan de Kreuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 5-Phosphatase Oculocerebrorenal Syndrome of Lowe Protein (OCRL) Controls Actin Dynamics during Early Steps ofListeria monocytogenesInfection

(2012) Andreas Kühbacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate

(2012) A. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OCRL1 Modulates Cilia Length in Renal Epithelial Cells

(2012) Youssef Rbaibi et al.   TRAFFIC

Clathrin-Mediated Endocytic Proteins are Involved in Regulating Mitotic Progression and Completion

(2012) Charlotte M. Smith et al.   TRAFFIC

Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL

(2012) Michelle Pirruccello et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Inositol 5-Phosphatase dOCRL Controls PI(4,5)P2 Homeostasis and Is Necessary for Cytokinesis

(2011) Khaled Ben El Kadhi et al.   CURRENT BIOLOGY

Synaptojanin 1-Mediated PI(4,5)P2 Hydrolysis Is Modulated by Membrane Curvature and Facilitates Membrane Fission

(2011) Belle Chang-Ileto et al.   DEVELOPMENTAL CELL

A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1

(2011) Xiaomin Hou et al.   EMBO JOURNAL

OCRL controls trafficking through early endosomes via PtdIns4,5P2-dependent regulation of endosomal actin

(2011) Mariella Vicinanza et al.   EMBO JOURNAL

Let's go bananas: revisiting the endocytic BAR code

(2011) Britta Qualmann et al.   EMBO JOURNAL

The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration

(2011) B.-J. de Kreuk et al.   JOURNAL OF CELL SCIENCE

Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis

(2011) C. G. Hansen et al.   JOURNAL OF CELL SCIENCE

Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting

(2011) Y. Senju et al.   JOURNAL OF CELL SCIENCE

The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway

(2011) Christopher J. Noakes et al.   MOLECULAR BIOLOGY OF THE CELL

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling

(2011) Michal Bohdanowicz et al.   MOLECULAR BIOLOGY OF THE CELL

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

(2011) Martin Harterink et al.   NATURE CELL BIOLOGY

Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis

(2011) Daphné Dambournet et al.   NATURE CELL BIOLOGY

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Bridging membrane and cytoskeleton dynamics in the secretory and endocytic pathways

(2011) Mihaela Anitei et al.   NATURE CELL BIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recognition of the F&H motif by the Lowe syndrome protein OCRL

(2011) Michelle Pirruccello et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lowe Syndrome Protein OCRL1 Supports Maturation of Polarized Epithelial Cells

(2011) Adam G. Grieve et al.   PLoS One

Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network

(2011) Felipe H. Santiago-Tirado et al.   TRENDS IN CELL BIOLOGY

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis

(2011) Marcus J. Taylor et al.   PLOS BIOLOGY

Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II

(2010) Atsushi Shimada et al.   FEBS LETTERS

Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin–AP-1-coated carrier biogenesis at the TGN

(2010) Mihaela Anitei et al.   NATURE CELL BIOLOGY

Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation

(2010) Y. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1

(2010) Laura E. Swan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase

(2009) Brian G. Coon et al.   HUMAN MOLECULAR GENETICS

Differential Clathrin Binding and Subcellular Localization of OCRL1 Splice Isoforms

(2009) Rawshan Choudhury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian phosphoinositide kinases and phosphatases

(2009) Takehiko Sasaki et al.   PROGRESS IN LIPID RESEARCH

Membrane traffic in the secretory pathway

(2008) M. Vicinanza et al.   CELLULAR AND MOLECULAR LIFE SCIENCES