Cerebrospinal fluid circulating tumour DNA genotyping and survival analysis in lung adenocarcinoma with leptomeningeal metastases

Genomic alterations of cerebrospinal fluid cell-free DNA in leptomeningeal metastases of gastric cancer

(2023) Xin Chen et al.   Journal of Translational Medicine

Pan-cancer whole-genome comparison of primary and metastatic solid tumours

(2023) Francisco Martínez-Jiménez et al.   NATURE

The evolution of lung cancer and impact of subclonal selection in TRACERx

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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial

(2023) Juliann Chmielecki et al.   Nature Communications

The Genomic Landscape of Melanoma and Its Therapeutic Implications

(2023) Ting-Ting Yang et al.   Genes

Gene alternation of cerebrospinal fluid in patients with leptomeningeal metastases of lung adenocarcinoma using next-generation sequencing

(2022) Hainan Yang et al.   BMC CANCER

Glioma progression is shaped by genetic evolution and microenvironment interactions

(2022) Frederick S. Varn et al.   CELL

Landscape of somatic alterations in large-scale solid tumors from an Asian population

(2022) Liqun Wu et al.   Nature Communications

Genotyping of cerebrospinal fluid in lung cancer patients with leptomeningeal metastasis

(2022) Naifu Nie et al.   Thoracic Cancer

Liquid biopsy: current technology and clinical applications

(2022) Mina Nikanjam et al.   Journal of Hematology & Oncology

Sequencing of cerebrospinal fluid in non‐small‐cell lung cancer patients with leptomeningeal metastasis: A systematic review

(2022) Tianqi Gao et al.   Cancer Medicine

Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)

(2022) Meichen Li et al.   BMC Medicine

Human TERT promoter mutations as a prognostic biomarker in glioma

(2021) Branka Powter et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Liquid Biopsy: From Discovery to Clinical Application

(2021) Catherine Alix-Panabières et al.   Cancer Discovery

FOXL2 and TERT promoter mutation detection in circulating tumor DNA of adult granulosa cell tumors as biomarker for disease monitoring

(2021) Jolijn W. Groeneweg et al.   GYNECOLOGIC ONCOLOGY

Mechanisms and management of 3rd‑generation EGFR‑TKI resistance in advanced non‑small cell lung cancer (Review)

(2021) Jingyi He et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Toward personalized treatment approaches for non-small-cell lung cancer

(2021) Meina Wang et al.   NATURE MEDICINE

Global, regional, and national cancer incidence and death for 29 cancer groups in 2019 and trends analysis of the global cancer burden, 1990–2019

(2021) Longfei Lin et al.   Journal of Hematology & Oncology

Programmable base editing of mutated TERT promoter inhibits brain tumour growth

(2020) Xinjian Li et al.   NATURE CELL BIOLOGY

Detection of genes mutations in cerebrospinal fluid circulating tumor DNA from neoplastic meningitis patients using next generation sequencing

(2020) Yue Zhao et al.   BMC CANCER

Prognostic value of TP53 co-mutation status combined with EGFR mutation in patients with lung adenocarcinoma

(2020) Feng Wang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Association of Cerebrospinal Fluid Tumor DNA Genotyping With Survival Among Patients With Lung Adenocarcinoma and Central Nervous System Metastases

(2020) Yang-Si Li et al.   JAMA Network Open

Genotyping of cerebrospinal fluid associated with osimertinib response and resistance for leptomeningeal metastases in EGFR-mutated non-small cell lung cancer

(2020) Mei-Mei Zheng et al.   Journal of Thoracic Oncology

TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti‐CTLA4 treatment

(2020) Huahua Li et al.   Cancer Medicine

The clinical characteristic and prognostic factors of leptomeningeal metastasis in patients with non‐small‐cell lung cancer‐a retrospective study from one single cancer institute

(2019) Weiwei Yan et al.   Cancer Medicine

Evaluating the cerebrospinal fluid ctDNA detection by next-generation sequencing in the diagnosis of meningeal Carcinomatosis

(2019) Yue Zhao et al.   BMC Neurology

Unique genetic profiles from cerebrospinal fluid cell-free DNA in leptomeningeal metastases of EGFR-mutant non-small-cell lung cancer: a new medium of liquid biopsy

(2018) Y S Li et al.   ANNALS OF ONCOLOGY

Leptomeningeal Metastases

(2018) Jerome J. Graber et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Leptomeningeal metastases in non-small-cell lung cancer

(2018) Haiying Cheng et al.   LANCET ONCOLOGY

Primary resistance to osimertinib due to SCLC transformation: Issue of T790M determination on liquid re-biopsy

(2018) R. Minari et al.   LUNG CANCER

Assessment of Resistance Mechanisms and Clinical Implications in Patients With EGFR T790M–Positive Lung Cancer and Acquired Resistance to Osimertinib

(2018) Geoffrey R. Oxnard et al.   JAMA Oncology

Sequential liquid biopsies reveal dynamic alterations of EGFR driver mutations and indicate EGFR amplification as a new mechanism of resistance to osimertinib in NSCLC

(2017) Franciele H. Knebel et al.   LUNG CANCER

METCopy Number Gain Is Associated with Gefitinib Resistance in Leptomeningeal Carcinomatosis ofEGFR-mutant Lung Cancer

(2017) Shigeki Nanjo et al.   MOLECULAR CANCER THERAPEUTICS

Cerebrospinal fluid circulating tumor cells: a novel tool to diagnose leptomeningeal metastases from epithelial tumors

(2017) Xuling Lin et al.   NEURO-ONCOLOGY

Capturing Genomic Evolution of Lung Cancers through Liquid Biopsy for Circulating Tumor DNA

(2017) Michael Offin et al.   Journal of Oncology

TERTpromoter mutations and long-term survival in patients with thyroid cancer

(2016) Tae Hyuk Kim et al.   ENDOCRINE-RELATED CANCER

Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid

(2016) Elena I. Pentsova et al.   JOURNAL OF CLINICAL ONCOLOGY

Leptomeningeal Metastases in Patients with NSCLC with EGFR Mutations

(2016) Yang-Si Li et al.   Journal of Thoracic Oncology

Role of EGFR mutations in lung cancers: prognosis and tumor chemosensitivity

(2015) Kenichi Suda et al.   ARCHIVES OF TOXICOLOGY

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

(2015) Leticia De Mattos-Arruda et al.   Nature Communications

TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma

(2014) Klaus G. Griewank et al.   JNCI-Journal of the National Cancer Institute

TERT promoter mutations contribute to subset prognostication of lower-grade gliomas

(2014) Aden Ka-Yin Chan et al.   MODERN PATHOLOGY

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

EGFR Mutations Predict Survival Benefit From Gefitinib in Patients With Advanced Lung Adenocarcinoma: A Historical Comparison of Patients Treated Before and After Gefitinib Approval in Japan

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