Proteome-scale Binary Interactomics in Human Cells

Current Experimental Methods for Characterizing Protein-Protein Interactions

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OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination

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A combined binary interaction and phenotypic map of C. elegans cell polarity proteins

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The ORFeome Collaboration: a genome-scale human ORF-clone resource

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Trapping mammalian protein complexes in viral particles

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Alternative Reagents for Methotrexate as Immobilizing Anchor Moieties in the Optimization of MASPIT: Synthesis and Biological Evaluation

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Fundamentals of protein interaction network mapping

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EARP is a multisubunit tethering complex involved in endocytic recycling

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A Proteome-Scale Map of the Human Interactome Network

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A Combined “Omics” Approach Identifies N-Myc Interactor as a Novel Cytokine-induced Regulator of IRE1α Protein and c-Jun N-terminal Kinase in Pancreatic Beta Cells

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Kinase Substrate Sensor (KISS), a MammalianIn SituProtein Interaction Sensor

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Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

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Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack

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A “Clickable” MTX Reagent as a Practical Tool for Profiling Small-Molecule-Intracellular Target Interactions via MASPIT

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Target deconvolution techniques in modern phenotypic profiling

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STRIPAK complexes: Structure, biological function, and involvement in human diseases

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Reciprocal cross-regulation between RNF41 and USP8 controls cytokine receptor sorting and processing

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The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

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Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

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Reversine, a 2,6-disubstituted Purine, as an Anti-cancer Agent in Differentiated and Undifferentiated Thyroid Cancer Cells

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RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

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A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis

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A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

Modulation of Pantothenate Kinase 3 Activity by Small Molecules that Interact with the Substrate/Allosteric Regulatory Domain

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Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

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Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity

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Far-red fluorescent tags for protein imaging in living tissues

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Array MAPPIT: High-Throughput Interactome Analysis in Mammalian Cells

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Abrogation of the Brd4-Positive Transcription Elongation Factor b Complex by Papillomavirus E2 Protein Contributes to Viral Oncogene Repression

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The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)

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Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells

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DAX-1 (Dosage-Sensitive Sex Reversal-Adrenal Hypoplasia Congenita Critical Region on the X-Chromosome, Gene 1) Selectively Inhibits Transactivation But Not Transrepression Mediated by the Glucocorticoid Receptor in a LXXLL-Dependent Manner

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An experimentally derived confidence score for binary protein-protein interactions

(2008) Pascal Braun et al.   NATURE METHODS

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

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