Kinase Substrate Sensor (KISS), a MammalianIn SituProtein Interaction Sensor

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

(2014) Julia Petschnigg et al.   NATURE METHODS

An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions

(2014) Emmanuelle Tchekanda et al.   NATURE METHODS

Targeting Protein-Protein Interaction by Small Molecules

(2013) Lingyan Jin et al.   Annual Review of Pharmacology and Toxicology

A “Clickable” MTX Reagent as a Practical Tool for Profiling Small-Molecule-Intracellular Target Interactions via MASPIT

(2013) Martijn D. P. Risseeuw et al.   ChemMedChem

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

(2013) Michal Simicek et al.   NATURE CELL BIOLOGY

Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system

(2013) Ben C Collins et al.   NATURE METHODS

Structural Basis of the Unfolded Protein Response

(2012) Alexei Korennykh et al.   Annual Review of Cell and Developmental Biology

Modeling Transcriptome Dynamics in a Complex World

(2012) Philipp A. Jaeger et al.   CELL

The use of mammalian two-hybrid technologies for high-throughput drug screening

(2012) Sam Lievens et al.   METHODS

Diversity in Genetic In Vivo Methods for Protein-Protein Interaction Studies: from the Yeast Two-Hybrid System to the Mammalian Split-Luciferase System

(2012) B. Stynen et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Dissection of DNA Damage Responses Using Multiconditional Genetic Interaction Maps

(2012) Aude Guénolé et al.   MOLECULAR CELL

Differential network biology

(2012) Trey Ideker et al.   Molecular Systems Biology

Strategies for membrane interaction proteomics: No mass spectrometry required

(2012) Mandy H. Y. Lam et al.   PROTEOMICS

MAPPIT: A protein interaction toolbox built on insights in cytokine receptor signaling

(2011) Sam Lievens et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor

(2011) Nicolas Bisson et al.   NATURE BIOTECHNOLOGY

A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis

(2011) Christopher Chidley et al.   Nature Chemical Biology

Yeast two-hybrid methods and their applications in drug discovery

(2011) Amel Hamdi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Recent advances in charting protein–protein interaction: mass spectrometry-based approaches

(2010) Anne-Claude Gavin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Exhaustive benchmarking of the yeast two-hybrid system

(2010) Yu-Chi Chen et al.   NATURE METHODS

Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

(2010) L. M. Luttrell et al.   PHARMACOLOGICAL REVIEWS

Array MAPPIT: High-Throughput Interactome Analysis in Mammalian Cells

(2009) Sam Lievens et al.   JOURNAL OF PROTEOME RESEARCH

Recent advances and method development for drug target identification

(2009) Janet N.Y. Chan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

MAPPIT (MAmmalian Protein–Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells

(2008) Els Pattyn et al.   JOURNAL OF VIROLOGICAL METHODS

An experimentally derived confidence score for binary protein-protein interactions

(2008) Pascal Braun et al.   NATURE METHODS