Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes

The sulfotransferase XB5850668.L is required to apportion embryonic ectodermal domains

(2023) Alexander Marchak et al.   DEVELOPMENTAL DYNAMICS

Phenotypic and molecular basis of SIX1 variants linked to non-syndromic deafness and atypical branchio-otic syndrome in South Korea

(2023) Somin Lee et al.   Scientific Reports

Investigating Zmym2 and Zmym4 as Putative Six1 Co‐Factors

(2022) Karyn Jourdeuil et al.   FASEB JOURNAL

Mcrs1 is required for branchial arch and cranial cartilage development

(2022) Stephanie Keer et al.   DEVELOPMENTAL BIOLOGY

The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest

(2022) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Genetic and Non-genetic Workup for Pediatric Congenital Hearing Loss

(2021) Ryan Belcher et al.   Frontiers in Pediatrics

Sobp modulates the transcriptional activation of Six1 target genes and is required during craniofacial development

(2021) Andre L. P. Tavares et al.   DEVELOPMENT

Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development

(2020) Ankita M. Shah et al.   Disease Models & Mechanisms

Six1 and Irx1 have reciprocal interactions during cranial placode and otic vesicle formation

(2018) Charles H. Sullivan et al.   DEVELOPMENTAL BIOLOGY

Congenital hearing loss

(2017) Anna M. H. Korver et al.   Nature Reviews Disease Primers

An improved smaller biotin ligase for BioID proximity labeling

(2016) Dae In Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Genome evolution in the allotetraploid frog Xenopus laevis

(2016) Adam M. Session et al.   NATURE

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes

(2016) Nick Riddiford et al.   eLife

Using Xenopus to discover new genes involved in branchiootorenal spectrum disorders

(2015) Sally A. Moody et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

A conserved transcriptional network regulates lamina development in the Drosophila visual system

(2014) Cristina Piñeiro et al.   DEVELOPMENT

Establishing the pre-placodal region and breaking it into placodes with distinct identities

(2014) Jean-Pierre Saint-Jeannet et al.   DEVELOPMENTAL BIOLOGY

The Drosophila Wilms׳ Tumor 1-Associating Protein (WTAP) homolog is required for eye development

(2014) Abigail M. Anderson et al.   DEVELOPMENTAL BIOLOGY

Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development

(2014) Bo Yan et al.   DEVELOPMENTAL DYNAMICS

Regulation of Drosophila Eye Development by the Transcription Factor Sine oculis

(2014) Barbara Jusiak et al.   PLoS One

ErbB3 binding protein-1 (Ebp1) controls proliferation and myogenic differentiation of muscle stem cells

(2013) Nicolas Figeac et al.   DEVELOPMENTAL BIOLOGY

Onset of atonal expression in Drosophila retinal progenitors involves redundant and synergistic contributions of Ey/Pax6 and So binding sites within two distant enhancers

(2013) Qingxiang Zhou et al.   DEVELOPMENTAL BIOLOGY

Biallelic genome modification in F0Xenopus tropicalisembryos using the CRISPR/Cas system

(2013) Ira L. Blitz et al.   GENESIS

Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis inXenopus tropicalis

(2013) Takuya Nakayama et al.   GENESIS

Homoeologous chromosomes of Xenopus laevis are highly conserved after whole-genome duplication

(2013) Y Uno et al.   HEREDITY

Structure-function analyses of the human SIX1–EYA2 complex reveal insights into metastasis and BOR syndrome

(2013) Aaron N Patrick et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pax3 and Zic1 drive induction and differentiation of multipotent, migratory, and functional neural crest in Xenopus embryos

(2013) C. Milet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the Xenopus laevis inner ear transcriptome for biological function

(2012) TuShun R Powers et al.   BMC GENOMICS

The peripheral sensory nervous system in the vertebrate head: A gene regulatory perspective

(2012) Timothy Grocott et al.   DEVELOPMENTAL BIOLOGY

Xenopuswhite papers and resources: Folding functional genomics and genetics into the frog

(2012) Mustafa K. Khokha   GENESIS

From expression cloning to gene modeling: The development ofXenopusgene sequence resources

(2012) Michael J. Gilchrist   GENESIS

Audiovestibular findings in a branchio-oto syndrome patient with aSIX1mutation

(2011) Yoshihiro Noguchi et al.   ACTA OTO-LARYNGOLOGICA

Balancing cell numbers during organogenesis: Six1a differentially affects neurons and sensory hair cells in the inner ear

(2011) Olivier Bricaud et al.   DEVELOPMENTAL BIOLOGY

A novel dominant mutation in SIX1, affecting a highly conserved residue, result in only auditory defects in humans

(2011) Mohamed Ali Mosrati et al.   European Journal of Medical Genetics

Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development

(2011) Keiko Ikeda et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Xenopus research: metamorphosed by genetics and genomics

(2011) Richard M. Harland et al.   TRENDS IN GENETICS

SOBP Is Mutated in Syndromic and Nonsyndromic Intellectual Disability and Is Highly Expressed in the Brain Limbic System

(2010) Efrat Birk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

HERV-mediated genomic rearrangement of EYA1 in an individual with branchio-oto-renal syndrome

(2010) Amarilis Sanchez-Valle et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Genetic interactions of eyes absent, twin of eyeless and orthodenticle regulate sine oculis expression during ocellar development in Drosophila

(2010) Jorge Blanco et al.   DEVELOPMENTAL BIOLOGY

Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base

(2010) Guiyuan He et al.   DEVELOPMENTAL BIOLOGY

Developmental expression patterns of candidate cofactors for vertebrate six family transcription factors

(2010) Karen M. Neilson et al.   DEVELOPMENTAL DYNAMICS

Mechanics of the frog ear

(2010) Pim Van Dijk et al.   HEARING RESEARCH

Mutation screening of the EYA1, SIX1, and SIX5 genes in a large cohort of patients harboring branchio-oto-renal syndrome calls into question the pathogenic role of SIX5 mutations

(2010) Pauline Krug et al.   HUMAN MUTATION

The Genome of the Western Clawed Frog Xenopus tropicalis

(2010) U. Hellsten et al.   SCIENCE

EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis

(2009) Youe Li et al.   BIOLOGY OF THE CELL

Catweasel mice: A novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome

(2009) Erika A. Bosman et al.   DEVELOPMENTAL BIOLOGY

Activation of Six1 target genes is required for sensory placode formation

(2009) Nicolas A.D. Christophorou et al.   DEVELOPMENTAL BIOLOGY

Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish andXenopus

(2009) Grant N. Wheeler et al.   DEVELOPMENTAL DYNAMICS

Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor

(2009) Suk-Kyeong Jung et al.   FASEB JOURNAL

Biochemical and Functional Characterization of SixSIX1Branchio-oto-renal Syndrome Mutations

(2009) Aaron N. Patrick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-type-specific transcription of prospero is controlled by combinatorial signaling in the Drosophila eye

(2008) T. Hayashi et al.   DEVELOPMENT

Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion

(2008) Gerhard Schlosser et al.   DEVELOPMENTAL BIOLOGY

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4

(2008) Binglai Chen et al.   DEVELOPMENTAL BIOLOGY

SIX1mutation screening in 247 branchio-oto-renal syndrome families: a recurrent missense mutation associated with BOR

(2008) Amit Kochhar et al.   HUMAN MUTATION

Mechanics of the exceptional anuran ear

(2008) Richard L. M. Schoffelen et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY

Jxc1/Sobp, Encoding a Nuclear Zinc Finger Protein, Is Critical for Cochlear Growth, Cell Fate, and Patterning of the Organ of Corti

(2008) Z. Chen et al.   JOURNAL OF NEUROSCIENCE

ZNF198 Stabilizes the LSD1–CoREST–HDAC1 Complex on Chromatin through Its MYM-Type Zinc Fingers

(2008) Christian B. Gocke et al.   PLoS One