Jianpi Huayu Decoction suppresses cellular senescence in colorectal cancer via p53-p21-Rb pathway: Network pharmacology and in vivo validation

Targets Involved in the Anti-Cancer Activity of Quercetin in Breast, Colorectal and Liver Neoplasms

(2023) Alessandro Maugeri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cell cycle regulation: p53-p21-RB signaling

(2022) Kurt Engeland   CELL DEATH AND DIFFERENTIATION

DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)

(2022) Brad T Sherman et al.   NUCLEIC ACIDS RESEARCH

Cellular senescence: the good, the bad and the unknown

(2022) Weijun Huang et al.   Nature Reviews Nephrology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Diagnosis and Treatment of Metastatic Colorectal Cancer

(2021) Leah H. Biller et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humans

(2021) Ricardo I. Martínez‐Zamudio et al.   AGING CELL

Online Mendelian Inheritance in Man ( OMIM ®): Victor McKusick 's magnum opus

(2021) Ada Hamosh et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings

(2021) Jerome Eberhardt et al.   Journal of Chemical Information and Modeling

Network pharmacology: curing causal mechanisms instead of treating symptoms

(2021) Cristian Nogales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Integrated strategy for accurately screening biomarkers based on metabolomics coupled with network pharmacology

(2020) Wendan Zhang et al.   TALANTA

Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours

(2020) Ellen Brenner et al.   Nature Communications

MDM2 inhibition: an important step forward in cancer therapy

(2020) Marina Konopleva et al.   LEUKEMIA

Anticancer activities of TCM and their active components against tumor metastasis

(2020) Kailong Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Senescence and the SASP: many therapeutic avenues

(2020) Jodie Birch et al.   GENES & DEVELOPMENT

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence

(2019) Jie-Yu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Luteolin, a flavonoid, as an anticancer agent: A review

(2019) Muhammad Imran et al.   BIOMEDICINE & PHARMACOTHERAPY

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

(2019) Antoine Daina et al.   NUCLEIC ACIDS RESEARCH

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Cellular Senescence: Aging, Cancer, and Injury

(2019) Arianna Calcinotto et al.   PHYSIOLOGICAL REVIEWS

Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

(2019) Lawrence A. Donehower et al.   Cell Reports

RCSB Protein Data Bank: Enabling biomedical research and drug discovery

(2019) David S. Goodsell et al.   PROTEIN SCIENCE

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency syndrome

(2019) Qiqi Zhao et al.   Frontiers of Medicine

Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

(2019) Si-Min Tang et al.   BIOMEDICINE & PHARMACOTHERAPY

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

An updated dose–response meta-analysis of coffee consumption and liver cancer risk

(2016) Chengbo Yu et al.   Scientific Reports

Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα

(2015) Odaine N. Gordon et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A systematic review of anticancer effects of Radix Astragali

(2015) Yeehong Jung et al.   Chinese Journal of Integrative Medicine

Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis

(2015) Song-yang Xi et al.   Evidence-based Complementary and Alternative Medicine

jvenn: an interactive Venn diagram viewer

(2014) Philippe Bardou et al.   BMC BIOINFORMATICS

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

A Novel Integrated Method for Large-Scale Detection, Identification, and Quantification of Widely Targeted Metabolites: Application in the Study of Rice Metabolomics

(2013) Wei Chen et al.   Molecular Plant

Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells

(2013) S Belluti et al.   Cell Death & Disease

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Real-Time PyMOL Visualization for Rosetta and PyRosetta

(2011) Evan H. Baugh et al.   PLoS One

The Use of Immunohistochemistry for Biomarker Assessment—Can It Compete with Other Technologies?

(2011) Robert W. Dunstan et al.   TOXICOLOGIC PATHOLOGY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY