Design, synthesis, biological evaluation and molecular docking study of novel pleuromutilin derivatives containing substituted benzoxazole as antibacterial agents

Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups

(2022) Qi Wang et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Design, synthesis, in vitro and in vivo evaluation against MRSA and molecular docking studies of novel pleuromutilin derivatives bearing 1, 3, 4-oxadiazole linker

(2021) Jie Liu et al.   BIOORGANIC CHEMISTRY

Design, synthesis and biological evaluation of pleuromutilin-Schiff base hybrids as potent anti-MRSA agents in vitro and in vivo

(2021) Bo Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthetic transformations and biological screening of benzoxazole derivatives: A review

(2020) Rabia Sattar et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA)

(2020) Hua-Li Qin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against Staphylococcus aureus with Defined Resistance Mechanisms

(2020) Povilas Kavaliauskas et al.   Antibiotics-Basel

Natural Products in the “Marketplace”: Interfacing Synthesis and Biology

(2019) Benjamin J. Huffman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Leave it to Lefamulin: A Pleuromutilin Treatment Option in Community-Acquired Bacterial Pneumonia

(2019) Young Ran Lee et al.   DRUGS

Design, synthesis and biological evaluation of novel pleuromutilin derivatives possessing acetamine phenyl linker

(2019) Zhen Jin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzoxazole derivatives: design, synthesis and biological evaluation

(2018) Saloni Kakkar et al.   Chemistry Central Journal

Inhibition of pro-inflammatory mediators in RAW264.7 cells by 7-hydroxyflavone and 7,8-dihydroxyflavone

(2017) Zhen Jin et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Design, synthesis, and structure-activity relationship studies of novel pleuromutilin derivatives having a piperazine ring

(2016) Jian Luo et al.   Chemical Biology & Drug Design

Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction

(2016) Ijaz Ahmad et al.   Biomed Research International

Pleuromutilins: use in food-producing animals in the European Union, development of resistance and impact on human and animal health

(2014) E. van Duijkeren et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic

(2010) M. Z. David et al.   CLINICAL MICROBIOLOGY REVIEWS

Methicillin-resistant Staphylococcus aureus: the superbug

(2010) Giuseppe Ippolito et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

In vitro activity of retapamulin against Staphylococcus aureus isolates resistant to fusidic acid and mupirocin

(2008) N. Woodford et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY