Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against Staphylococcus aureus with Defined Resistance Mechanisms

Staphylococcus aureus Biofilm Infection Compromises Wound Healing by Causing Deficiencies in Granulation Tissue Collagen

(2019) Sashwati Roy et al.   ANNALS OF SURGERY

Large variations in clinical antibiotic activity against Staphylococcus aureus biofilms of periprosthetic joint infection isolates

(2019) Jonathan B. Mandell et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation

(2019) Katrine Qvortrup et al.   Frontiers in Chemistry

Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features

(2019) Yanguang Cong et al.   Journal of Advanced Research

Heterocyclization of polarized system: synthesis, antioxidant and anti-inflammatory 4-(pyridin-3-yl)-6-(thiophen-2-yl) pyrimidine-2-thiol derivatives

(2018) Wesam S. Shehab et al.   Chemistry Central Journal

ProTox-II: a webserver for the prediction of toxicity of chemicals

(2018) Priyanka Banerjee et al.   NUCLEIC ACIDS RESEARCH

Design and synthesis of 5-(5-nitrothiophen-2-yl)-3-phenyl-4,5-dihydro-1H-pyrazole derivatives with improved solubility and potential antituberculosis activity

(2018) Mihir Khambete et al.   Chemical Biology & Drug Design

Therapeutic importance of synthetic thiophene

(2018) Rashmi Shah et al.   Chemistry Central Journal

Heparin Mimics Extracellular DNA in Binding to Cell Surface-Localized Proteins and Promoting Staphylococcus aureus Biofilm Formation

(2017) Surabhi Mishra et al.   mSphere

Synthesis and Structure-Activity Relationship of Some New Thiophene-Based Heterocycles as Potential Antimicrobial Agents

(2016) Yahia Mabkhot et al.   MOLECULES

In VitroActivity of Tigecycline AgainstOrientia tsutsugamushi

(2016) Sun-Myoung Lee et al.   YONSEI MEDICAL JOURNAL

Commensal Protection of Staphylococcus aureus against Antimicrobials by Candida albicans Biofilm Matrix

(2016) Eric F. Kong et al.   mBio

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

(2015) Douglas E. V. Pires et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transcriptome analysis of the biofilm formed by methicillin-susceptible Staphylococcus aureus

(2015) Xiaojuan Tan et al.   Scientific Reports

Bioactivation Potential of Thiophene-Containing Drugs

(2014) Darja Gramec et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Synthesis of novel 1,2,4-triazoles, triazolothiadiazines and triazolothiadiazoles as potential anticancer agents

(2014) Mona M. Kamel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Assessment of the genotoxic and carcinogenic potentials of 3-aminothiophene derivatives usingin vitroandin silicomethodologies

(2013) Alban Lepailleur et al.   JOURNAL OF APPLIED TOXICOLOGY

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

(2013) Timothy J. Foster et al.   NATURE REVIEWS MICROBIOLOGY

DING Proteins from Phylogenetically Different Species Share High Degrees of Sequence and Structure Homology and Block Transcription of HIV-1 LTR Promoter

(2013) Rakhee Sachdeva et al.   PLoS One

Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure–activity study

(2012) Erik Chorell et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Deciphering mechanisms of staphylococcal biofilm evasion of host immunity

(2012) Mark L. Hanke et al.   Frontiers in Cellular and Infection Microbiology

Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria

(2011) Adebola Onanuga et al.   JOURNAL OF HEALTH POPULATION AND NUTRITION

Staphylococcus aureusbiofilms

(2011) Nathan K. Archer et al.   Virulence

Microtiter Dish Biofilm Formation Assay

(2011) George A. O'Toole   Jove-Journal of Visualized Experiments

The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

(2010) A Rossi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rational Design and Synthesis of 2,2-Bisheterocycle Tandem Derivatives as Non-Nucleoside Hepatitis B Virus Inhibitors

(2008) Hai-Jun Chen et al.   ChemMedChem

Comparison of biofilm-associated cell survival following in vitro exposure of meticillin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin

(2008) Karen Smith et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus

(2008) W. E. Rose et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY