Investigation of drug-polymer miscibility and design of ternary solid dispersions for oral bioavailability enhancement by hot melt extrusion

Investigation on co-solvency, solvent effect, Hansen solubility parameter and preferential solvation of fenbufen dissolution and models correlation

(2022) Yang Cong et al.   JOURNAL OF MOLECULAR LIQUIDS

Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs

(2022) Kifayat Ullah Khan et al.   LIFE SCIENCES

Drug-Carrier Miscibility in Solid Dispersions of Glibenclamide and a Novel Approach to Enhance Its Solubility Using an Effervescent Agent

(2022) Muralidhar Pisay et al.   AAPS PHARMSCITECH

Itraconazole Amorphous Solid Dispersion Tablets: Formulation and Compaction Process Optimization Using Quality by Design Principles and Tools

(2022) Hetvi Triboandas et al.   Pharmaceutics

Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats

(2021) Yousef A. Bin Jardan et al.   SAUDI PHARMACEUTICAL JOURNAL

Acoustic levitation and high-resolution synchrotron X-ray powder diffraction: A fast screening approach of niclosamide amorphous solid dispersions

(2021) Eduardo J. Barbosa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Material-sparing Approach Using Differential Scanning Calorimeter and Response Surface Methodology for Process Optimization of Hot-Melt Extrusion

(2021) Hemanth K. Mamidi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Metamorphosis of Twin Screw Extruder-Based Granulation Technology: Applications Focusing on Its Impact on Conventional Granulation Technology

(2021) Rajat Radhakrishna Rao et al.   AAPS PHARMSCITECH

Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs

(2019) Phuong Tran et al.   Pharmaceutics

Influence of glass forming ability on the physical stability of supersaturated amorphous solid dispersions

(2019) Lasse Ingerslev Blaabjerg et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Impact of sodium citrate on structural properties of gluten

(2019) Amir Amiri et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Hot-melt extrusion process impact on polymer choice of glyburide solid dispersions: The effect of wettability and dissolution

(2019) Maen Alshafiee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of mechanical and thermal energy on nifedipine amorphous solid dispersions prepared by hot melt extrusion: Preparation and physical stability

(2019) Xiangyu Ma et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Is prodrug design an approach to increase water solubility?

(2019) Bruna M.A. Sanches et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Studying tautomerism in an important pharmaceutical glibenclamide confined in the thin nanometric layers

(2019) K. Wolnica et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Molecular simulation driven experiment for formulation of fixed dose combination of Darunavir and Ritonavir as anti-HIV nanosuspension

(2019) Chetan Hasmukh Mehta et al.   JOURNAL OF MOLECULAR LIQUIDS

Investigation of drug-polymer miscibility, biorelevant dissolution, and bioavailability improvement of Dolutegravir-polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer solid dispersions

(2019) Dani Lakshman et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Interaction of Sulfonylureas with Liver Uptake Transporters OATP1B1 and OATP1B3

(2018) Yu Chen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Oral Delivery of Highly Lipophilic, Poorly Water-Soluble Drugs: Self-Emulsifying Drug Delivery Systems to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a Cholesteryl Ester Transfer Protein Inhibitor in Preclinical Species

(2018) Xue-Qing Chen et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Investigating the molecular dissolution process of binary solid dispersions by molecular dynamics simulations

(2018) TengIan Chan et al.   Asian Journal of Pharmaceutical Sciences

The relevance of co-amorphous formulations to develop supersaturated dosage forms: In-vitro, and ex-vivo investigation of Ritonavir-Lopinavir co-amorphous materials

(2018) V. Sai Krishna Anand et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate)

(2018) Romina Pezzoli et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Impact of method of preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of co-precipitation and spray drying

(2018) Hao Helen Hou et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Selection of the suitable polymer for supercritical fluid assisted preparation of carvedilol solid dispersions

(2018) Jelena Djuris et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Formulation performance and processability window for manufacturing a dual-polymer amorphous solid dispersion via hot-melt extrusion and strand pelletization

(2018) T.R. Hörmann et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of API-Polymer Miscibility and Interaction on the Stabilization of Amorphous Solid Dispersion: A Molecular Simulation Study

(2017) Yin Yani et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder

(2017) Hiroki Higashiyama et al.   JOURNAL OF ANATOMY

Enhancing bioavailability and controlling the release of glibenclamide from optimized solid lipid nanoparticles

(2017) Ibrahim A. Elbahwy et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

A review of dendritic growth during solidification: Mathematical modeling and numerical simulations

(2017) Mohamad Ali Jaafar et al.   RENEWABLE & SUSTAINABLE ENERGY REVIEWS

Optimising Drug Solubilisation in Amorphous Polymer Dispersions: Rational Selection of Hot-melt Extrusion Processing Parameters

(2016) Shu Li et al.   AAPS PHARMSCITECH

A new approach to produce drug nanosuspensions CO 2 -assisted effervescence to produce drug nanosuspensions

(2016) Xiangfei Han et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization

(2016) Navya Sree Kola Srinivas et al.   International Journal of Nanomedicine

Effervescence Assisted Fusion Technique to Enhance the Solubility of Drugs

(2015) Mohd Aftab Alam et al.   AAPS PHARMSCITECH

Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

(2015) Hemlata Patil et al.   AAPS PHARMSCITECH

Investigation and correlation of drug polymer miscibility and molecular interactions by various approaches for the preparation of amorphous solid dispersions

(2015) Fan Meng et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Investigation of phase diagrams and physical stability of drug–polymer solid dispersions

(2014) Jiannan Lu et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Preparation of carbamazepine–Soluplus® solid dispersions by hot-melt extrusion, and prediction of drug–polymer miscibility by thermodynamic model fitting

(2013) Jelena Djuris et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Construction of Drug–Polymer Thermodynamic Phase Diagrams Using Flory–Huggins Interaction Theory: Identifying the Relevance of Temperature and Drug Weight Fraction to Phase Separation within Solid Dispersions

(2012) Yiwei Tian et al.   MOLECULAR PHARMACEUTICS

Changes in the pharmacokinetics of glibenclamide in rats with streptozotocin-induced diabetes mellitus

(2012) Yuqing Li et al.   Acta Pharmaceutica Sinica B

Improving the Chemical Stability of Amorphous Solid Dispersion with Cocrystal Technique by Hot Melt Extrusion

(2011) Xu Liu et al.   PHARMACEUTICAL RESEARCH

Characterization of solid dispersions of itraconazole and vitamin E TPGS prepared by microwave technology

(2010) Mariarosa Moneghini et al.   Future Medicinal Chemistry