Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs
Authors
Keywords
-
Journal
Pharmaceutics
Volume 11, Issue 3, Pages 132
Publisher
MDPI AG
Online
2019-03-20
DOI
10.3390/pharmaceutics11030132
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hot-melt extrusion process impact on polymer choice of glyburide solid dispersions: The effect of wettability and dissolution
- (2019) Maen Alshafiee et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Storage stability and solubilization ability of HPMC in curcumin amorphous solid dispersions formulated by Eudragit E100
- (2018) Na Fan et al. CARBOHYDRATE POLYMERS
- Impact of HPMC on inhibiting crystallization and improving permeability of curcumin amorphous solid dispersions
- (2018) Na Fan et al. CARBOHYDRATE POLYMERS
- A trade-off between solubility enhancement and physical stability upon simultaneous amorphization and nanonization of curcumin in comparison to amorphization alone
- (2018) Jerome Jie Long Wong et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- A high-sensitivity HPLC-ELSD method for HPMC-AS quantification and its application in elucidating the release mechanism of HPMC-AS based amorphous solid dispersions
- (2018) Shan Wang et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Amorphous solid dispersions of darunavir: Comparison between spray drying and electrospraying
- (2018) Annelies Smeets et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility
- (2018) Maude Reggane et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Intermolecular interaction and solid state characterization of abietic acid/chitosan solid dispersions possessing antimicrobial and antioxidant properties
- (2018) Valentina Cuzzucoli Crucitti et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Engineering fast dissolving sodium acetate mediated crystalline solid dispersion of docetaxel
- (2018) Albert Nguessan Ngo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Enhancing the solubility and bioavailability of poorly water-soluble drugs using supercritical antisolvent (SAS) process
- (2018) Sharif Md Abuzar et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Investigations on solid dispersions of valsartan with alkalizing agents: Preparation, characterization and physicochemical properties
- (2018) Wenhao Xu et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Preparation and characterization of solid dispersions of celecoxib obtained by spray-drying ethanolic suspensions containing PVP-K30 or isomalt
- (2018) Saeed Motallae et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- pH-independent controlled release tablets containing nanonizing valsartan solid dispersions for less variable bioavailability in humans
- (2018) Jun-Bom Park et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Amorphous Solid Dispersion of Meloxicam Enhanced Oral Absorption in Rats With Impaired Gastric Motility
- (2018) Hiroki Suzuki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Hot Melt Extrusion as Solvent-Free Technique for a Continuous Manufacturing of Drug-Loaded Mesoporous Silica
- (2018) Natalja Genina et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Evaluation of Spironolactone Solid Dispersions Prepared by Co-Spray Drying With Soluplus ® and Polyvinylpyrrolidone and Influence of Tableting on Drug Release
- (2018) Nizar Al-Zoubi et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Continuous nanonization of lonidamine by modified-rapid expansion of supercritical solution process
- (2018) Biao-Qi Chen et al. JOURNAL OF SUPERCRITICAL FLUIDS
- Solubility measurement and preparation of nanoparticles of an anticancer drug (Letrozole) using rapid expansion of supercritical solutions with solid cosolvent (RESS-SC)
- (2018) Gholamhossein Sodeifian et al. JOURNAL OF SUPERCRITICAL FLUIDS
- Solid dispersion of dutasteride using the solvent evaporation method: Approaches to improve dissolution rate and oral bioavailability in rats
- (2018) Jin-Seok Choi et al. Materials Science & Engineering C-Materials for Biological Applications
- Disulfiram thermosensitive in-situ gel based on solid dispersion for cataract
- (2018) Chunjuan Zhang et al. Asian Journal of Pharmaceutical Sciences
- Development of Hot Melt Extruded Solid Dispersion of Tamoxifen Citrate and Resveratrol for Synergistic Effects on Breast Cancer Cells
- (2018) Nusrat Chowdhury et al. AAPS PHARMSCITECH
- Enhancement of the solubility, stability and bioaccessibility of quercetin using protein-based excipient emulsions
- (2018) Xing Chen et al. FOOD RESEARCH INTERNATIONAL
- Preparation of Lapatinib Ditosylate Solid Dispersions Using Solvent Rotary Evaporation and Hot Melt Extrusion for Solubility and Dissolution Enhancement
- (2018) Xian-Yue Hu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Electrospun amorphous solid dispersions of poorly water-soluble drugs: A review
- (2018) Deng-Guang Yu et al. JOURNAL OF CONTROLLED RELEASE
- Impact of method of preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of co-precipitation and spray drying
- (2018) Hao Helen Hou et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- PVP/ketoprofen coprecipitation using supercritical antisolvent process
- (2018) Paola Franco et al. POWDER TECHNOLOGY
- Effect of supersaturation on the oral bioavailability of paclitaxel/polymer amorphous solid dispersion
- (2018) Linlin Miao et al. Drug Delivery and Translational Research
- Extended Tacrolimus Release via the Combination of Lipid-based Solid Dispersion and HPMC Hydrogel Matrix Tablets
- (2018) Hui Xu et al. Asian Journal of Pharmaceutical Sciences
- Cooperative effect of polyvinylpyrrolidone and HPMC E5 on dissolution and bioavailability of nimodipine solid dispersions and tablets
- (2018) Zhisu Sun et al. Asian Journal of Pharmaceutical Sciences
- A dynamic in vitro permeation study on solid mono- and diacyl-phospholipid dispersions of celecoxib
- (2018) Ann-Christin Jacobsen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of plasticizers on manufacturing ritonavir/copovidone solid dispersions via hot-melt extrusion: Preformulation, physicochemical characterization, and pharmacokinetics in rats
- (2018) Yanna Zhao et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- A novel composition of ticagrelor by solid dispersion technique for increasing solubility and intestinal permeability
- (2018) Sung-Jin Kim et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Selection of the suitable polymer for supercritical fluid assisted preparation of carvedilol solid dispersions
- (2018) Jelena Djuris et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effects of Surfactants on Itraconazole-HPMCAS Solid Dispersion Prepared by Hot-Melt Extrusion I: Miscibility and Drug Release
- (2018) Nayan G. Solanki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhancing the aqueous solubility of curcumin at acidic condition through the complexation with whey protein nanofibrils
- (2018) Mehdi Mohammadian et al. FOOD HYDROCOLLOIDS
- Folate receptor targeted delivery of paclitaxel to breast cancer cells via folic acid conjugated graphene oxide grafted methyl acrylate nanocarrier
- (2018) Kandasamy Vinothini et al. BIOMEDICINE & PHARMACOTHERAPY
- Freeze dried solid dispersion of exemestane: A way to negate an aqueous solubility and oral bioavailability problems
- (2017) Shamandeep Kaur et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Tadalafil solid dispersion formulations based on PVP/VA S-630: Improving oral bioavailability in rats
- (2017) Jin-Seok Choi et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Melt extrusion vs. spray drying: The effect of processing methods on crystalline content of naproxen-povidone formulations
- (2017) Abbe Haser et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhanced pulmonary absorption of poorly soluble itraconazole by micronized cocrystal dry powder formulations
- (2017) Masatoshi Karashima et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Neurotoxic mechanisms of paclitaxel are local to the distal axon and independent of transport defects
- (2017) Erica L. Gornstein et al. EXPERIMENTAL NEUROLOGY
- Management of Hypersensitivity Reactions to Taxanes
- (2017) Matthieu Picard IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
- Improving the solubility of nilotinib through novel spray-dried solid dispersions
- (2017) Maikel Herbrink et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Use of acidifier and solubilizer in tadalafil solid dispersion to enhance the in vitro dissolution and oral bioavailability in rats
- (2017) Jin-Seok Choi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Enhancement of albendazole dissolution properties using solid dispersions with Gelucire 50/13 and PEG 15000
- (2017) Cesáreo J. Jiménez de los Santos et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Anomalous dissolution behavior of celecoxib in PVP/Isomalt solid dispersions prepared using spray drier
- (2017) Roya Ghanavati et al. Materials Science & Engineering C-Materials for Biological Applications
- Investigation of the in vitro performance difference of drug-Soluplus® and drug-PEG 6000 dispersions when prepared using spray drying or lyophilization
- (2017) Mohammad A. Altamimi et al. SAUDI PHARMACEUTICAL JOURNAL
- Application of hot melt extrusion to enhance the dissolution and oral bioavailability of oleanolic acid
- (2017) Nannan Gao et al. Asian Journal of Pharmaceutical Sciences
- Spray drying formulation of amorphous solid dispersions
- (2016) Abhishek Singh et al. ADVANCED DRUG DELIVERY REVIEWS
- Preparation and evaluation of azithromycin binary solid dispersions using various polyethylene glycols for the improvement of the drug solubility and dissolution rate
- (2016) Ehsan Adeli Brazilian Journal of Pharmaceutical Sciences
- Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique
- (2016) E. Sawicki et al. CANCER TREATMENT REVIEWS
- Poloxamer-based solid dispersions for oral delivery of docetaxel: Differential effects of F68 and P85 on oral docetaxel bioavailability
- (2016) Chung Kil Song et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Extension of the Hansen solubility parameter concept to the micronization of cyclotrimethylenetrinitramine crystals by supercritical anti-solvent process
- (2016) Bumjoon Seo et al. JOURNAL OF SUPERCRITICAL FLUIDS
- The use of supercritical anti-solvent (SAS) technique for preparation of Irbesartan-Pluronic® F-127 nanoparticles to improve the drug dissolution
- (2016) Ehsan Adeli POWDER TECHNOLOGY
- Development of amorphous dispersions of artemether with hydrophilic polymers via spray drying: Physicochemical and in silico studies
- (2016) Jaywant N. Pawar et al. Asian Journal of Pharmaceutical Sciences
- Preparation and characterization of spray-dried valsartan-loaded Eudragit® E PO solid dispersion microparticles
- (2016) Roshan Pradhan et al. Asian Journal of Pharmaceutical Sciences
- Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity
- (2016) Guru R. Valicherla et al. Scientific Reports
- Trastuzumab-cisplatin conjugates for targeted delivery of cisplatin to HER2-overexpressing cancer cells
- (2015) Rong Huang et al. BIOMEDICINE & PHARMACOTHERAPY
- Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion
- (2015) Rehmana Rashid et al. CARBOHYDRATE POLYMERS
- Sugars as solid dispersion carrier to improve solubility and dissolution of the BCS class II drug: clotrimazole
- (2015) Ashwini Madgulkar et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Preparation, characterization and in vitro/vivo evaluation of tectorigenin solid dispersion with improved dissolution and bioavailability
- (2015) Shuping Shuai et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Molecular interaction between glimepiride and Soluplus ® -PEG 4000 hybrid based solid dispersions: Characterisation and anti-diabetic studies
- (2015) Joy Nneji Reginald-Opara et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Strategies for formulating and delivering poorly water-soluble drugs
- (2015) Marta Rodriguez-Aller et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Dissolution study and thermal analysis of fenofibrate–Pluronic F127 solid dispersions
- (2015) Bożena Karolewicz et al. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
- Enhanced hypotensive effect of nimodipine solid dispersions produced by supercritical CO2 drying
- (2015) Manoela Klüppel Riekes et al. POWDER TECHNOLOGY
- Preparation and characterization of solid dispersion using a novel amphiphilic copolymer to enhance dissolution and oral bioavailability of sorafenib
- (2015) Duy Hieu Truong et al. POWDER TECHNOLOGY
- Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process
- (2015) Min-Soo Kim et al. Drug Design Development and Therapy
- Development of a rebamipide solid dispersion system with improved dissolution and oral bioavailability
- (2014) Roshan Pradhan et al. ARCHIVES OF PHARMACAL RESEARCH
- Solid dispersion of efavirenz in PVP K-30 by conventional solvent and kneading methods
- (2014) Lariza Darlene Santos Alves et al. CARBOHYDRATE POLYMERS
- Formulation and pharmacokinetics of gelucire solid dispersions of flurbiprofen
- (2014) Bhaskar Daravath et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Improved oral absorption and chemical stability of everolimus via preparation of solid dispersion using solvent wetting technique
- (2014) Sun Woo Jang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Baicalein–Nicotinamide Cocrystal with Enhanced Solubility, Dissolution, and Oral Bioavailability
- (2014) Yanting Huang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Amorphous Formulations of Indomethacin and Griseofulvin Prepared by Electrospinning
- (2014) Felipe L. Lopez et al. MOLECULAR PHARMACEUTICS
- The dissolution enhancement of piroxicam in its physical mixtures and solid dispersion formulations using gluconolactone and glucosamine hydrochloride as potential carriers
- (2014) Hiba Al-Hamidi et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Solid Dispersion in Pharmaceutical Drug Development: From Basics to Clinical Applications
- (2014) Punit Bhatnagar et al. Current Drug Delivery
- Development and evaluation of lafutidine solid dispersion via hot melt extrusion: Investigating drug-polymer miscibility with advanced characterisation
- (2014) Ritesh Fule et al. Asian Journal of Pharmaceutical Sciences
- Development of raloxifene-solid dispersion with improved oral bioavailability via spray-drying technique
- (2013) Tuan Hiep Tran et al. ARCHIVES OF PHARMACAL RESEARCH
- Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract
- (2013) Ryan C. Bennett et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Preparation of apigenin nanocrystals using supercritical antisolvent process for dissolution and bioavailability enhancement
- (2013) Jianjun Zhang et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs
- (2013) Chau Le-Ngoc Vo et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Experimental and mesoscale computational dynamics studies of the relationship between solubility and release of quercetin from PEG solid dispersions
- (2013) Daniel P. Otto et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Oral delivery of anticancer drugs: Challenges and opportunities
- (2013) Kaushik Thanki et al. JOURNAL OF CONTROLLED RELEASE
- Solid dispersions containing ursolic acid in Poloxamer 407 and PEG 6000: A comparative study of fusion and solvent methods
- (2013) Josimar Oliveira Eloy et al. POWDER TECHNOLOGY
- Preparation, characterization, and in vitro evaluation of folate-modified mesoporous bioactive glass for targeted anticancer drug carriers
- (2013) Hsiu-Mei Lin et al. Journal of Materials Chemistry B
- Physicochemical characterization and in vitro dissolution behavior of olanzapine-mannitol solid dispersions
- (2012) Venkateskumar Krishnamoorthy et al. Brazilian Journal of Pharmaceutical Sciences
- Incorporation of paclitaxel solid dispersions with poloxamer188 or polyethylene glycol to tune drug release from poly(ϵ-caprolactone) films
- (2012) Yanqing Shen et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- In vitroandin vivostudies on a novel solid dispersion of repaglinide using polyvinylpyrrolidone as the carrier
- (2012) Li-Fang Yin et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Amorphous-State Characterization of Efavirenz—Polymer Hot-Melt Extrusion Systems for Dissolution Enhancement
- (2012) Sateesh Kumar Sathigari et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Improved Human Bioavailability of Vemurafenib, a Practically Insoluble Drug, Using an Amorphous Polymer-Stabilized Solid Dispersion Prepared by a Solvent-Controlled Coprecipitation Process
- (2012) Navnit Shah et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dissolution rate enhancement of loratadine in polyvinylpyrrolidone K-30 solid dispersions by solvent methods
- (2012) Fernando Frizon et al. POWDER TECHNOLOGY
- Preparation and characterization of emulsified solid dispersions containing docetaxel
- (2011) Ying Chen et al. ARCHIVES OF PHARMACAL RESEARCH
- Physicochemical characterization and dissolution study of solid dispersions of diacerein with polyethylene glycol 6000
- (2011) Amit Kumar Aggarwal et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Lyophilization monophase solution technique for preparation of amorphous flutamide dispersions
- (2011) Nazik Elgindy et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Development and in-vivo assessment of the bioavailability of oridonin solid dispersions by the gas anti-solvent technique
- (2011) Songming Li et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications
- (2011) Yohei Kawabata et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Impact of CYP3A5*3 and CYP2C8-HapC on Paclitaxel/Carboplatin-Induced Myelosuppression in Patients with Ovarian Cancer
- (2011) Henrik Gréen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Surface-Active Derivative of Inulin (Inutec® SP1) Is a Superior Carrier for Solid Dispersions with a High Drug Load
- (2011) Parinda Srinarong et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Understanding the Performance of Melt-Extruded Poly(ethylene oxide)–Bicalutamide Solid Dispersions: Characterisation of Microstructural Properties Using Thermal, Spectroscopic and Drug Release Methods
- (2011) Osama A. Abu-Diak et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Preparation and evaluation of Cremophor-free paclitaxel solid dispersion by a supercritical antisolvent process
- (2011) Jae-Hyun Park et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Influence of Solvent Composition on the Miscibility and Physical Stability of Naproxen/PVP K 25 Solid Dispersions Prepared by Cosolvent Spray-Drying
- (2011) Amrit Paudel et al. PHARMACEUTICAL RESEARCH
- Silymarin-solid dispersions: Characterization and influence of preparation methods on dissolution
- (2010) Dalwadi Sonali et al. ACTA PHARMACEUTICA
- Solid dispersion of prednisolone: solid state characterization and improvement of dissolution profile
- (2010) Mohanraj Palanisamy et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Drug Targeting Strategies in Cancer Treatment: An Overview
- (2010) J. L. Arias MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Comparison Between Hot-Melt Extrusion and Spray-Drying for Manufacturing Solid Dispersions of the Graft Copolymer of Ethylene Glycol and Vinylalcohol
- (2010) Sandra Guns et al. PHARMACEUTICAL RESEARCH
- Introduction to Cancer Chemotherapeutics
- (2009) Donna S. Shewach et al. CHEMICAL REVIEWS
- Monolithic Osmotic Tablet Containing Solid Dispersion of 10-hydroxycamptothecin
- (2009) Huanhuan Chen et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Fusion processing of itraconazole solid dispersions by kinetisol® dispersing: A comparative study to hot melt extrusion
- (2009) James C. DiNunzio et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started